2026-03-15T20:12:40Z https://tokushima-u.repo.nii.ac.jp/oai

oai:tokushima-u.repo.nii.ac.jp:02011265 2025-04-28T06:38:56Z 1713853213384:1713853295607

A case of fatal multi-organ inflammation following COVID-19 vaccination Sudden death after COVID-19 vaccination 90335448 主田, 英之 ヌシダ, ヒデユキ Nushida, Hideyuki 主田 ヌシダ Nushida 英之 ヒデユキ Hideyuki 伊藤, 明日香 イトウ, アスカ Ito, Asuka 伊藤 イトウ Ito 明日香 アスカ Asuka クラタ, ヒロミツ クラタ, ヒロミツ Kurata, Hiromitsu ウメモト, ヒトミ ウメモト, ヒトミ Umemoto, Hitomi 30116842 德永, 逸夫 トクナガ, イツオ Tokunaga, Itsuo 德永 トクナガ Tokunaga 逸夫 イツオ Itsuo イセキ, ヒロフミ イセキ, ヒロフミ Iseki, Hirofumi 60283561 西村, 明儒 ニシムラ, アキヨシ Nishimura, Akiyoshi 西村 ニシムラ Nishimura 明儒 アキヨシ Akiyoshi open access © 2023. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/ Systemic inflammation Myopericarditis COVID-19 Vaccines Sudden death Autopsy A 14-year-old Japanese girl died unexpectedly 2 days after receiving the third dose of the BNT1262b2 mRNA COVID-19 vaccine. Autopsy findings showed congestive edema of the lungs, T-cell lymphocytic and macrophage infiltration in the lungs, pericardium, and myocardium of the left atria and left ventricle, liver, kidneys, stomach, duodenum, bladder, and diaphragm. Since there was no preceding infection, allergy, or drug toxicity exposure, the patient was diagnosed with post-vaccination pneumonia, myopericarditis, hepatitis, nephritis, gastroenteritis, cystitis, and myositis. Although neither type of inflammation is fatal by itself, arrhythmia is reported to be the most common cause of death in patients with atrial myopericarditis. In the present case, arrhythmia of atrial origin was assumed as the cause of cardiac failure and death. In sudden post-vaccination deaths, aggressive autopsy systemic search and histological examination involving extensive sectioning of the heart, including the atrium, are indispensable. Elsevier 2023-03-20 eng journal article AM 396569 https://tokushima-u.repo.nii.ac.jp/records/2011265 https://doi.org/10.1016/j.legalmed.2023.102244 10.1016/j.legalmed.2023.102244 18734162 13446223 AA11327981 AA11644485 Legal Medicine 63 102244 https://tokushima-u.repo.nii.ac.jp/record/2011265/files/legalmed_63_102244.pdf application/pdf 2.77 MB 2024-07-25