2026-03-15T21:21:48Z https://tokushima-u.repo.nii.ac.jp/oai

oai:tokushima-u.repo.nii.ac.jp:02012374 2025-04-28T06:57:27Z 1713853213384:1713853295607

Comparison of oral malodor and oral microbiome in smokers and non-smokers オカザワ, ユイ オカザワ, ユイ Okazawa, Yui 70189801 日野出, 大輔 ヒノデ, ダイスケ Hinode, Daisuke 日野出 ヒノデ Hinode 大輔 ダイスケ Daisuke 90243708 吉岡, 昌美 ヨシオカ, マサミ Yoshioka, Masami 吉岡 ヨシオカ Yoshioka 昌美 マサミ Masami 70747683 土井, 登紀子 ドイ, トキコ Doi, Tokiko 土井 ドイ Doi 登紀子 トキコ Tokiko 00709511 中江, 弘美 ナカエ, ヒロミ Nakae, Hiromi 中江 ナカエ Nakae 弘美 ヒロミ Hiromi 十川, 悠香 ソガワ, ユカ Sogawa, Yuka Grenier, Daniel open access Smoking Oral microbiome Periodontopathogenic bacteria Oral malodor Tongue coating Objective: The aim of this study was to investigate the influence of smoking on both the oral malodor and oral microbiome in smokers compared with a control group of non-smokers. Methods: The study population consisted of 37 patients with complete data for oral malodor, periodontal condition, and oral health behavior. The number of bacteria was determined by real-time PCR analysis. Results: Levels of hydrogen sulfide in smokers (n=9) were significantly higher than those from non-smokers (n=28). The mean numbers of total bacteria, Fusobacterium nucleatum and Campylobacter rectus recovered in saliva were significantly higher in smokers. In addition, a multiple linear regression analysis showed that smoking influenced oral microbiome. Bacteria in tongue coatings from 21 patients with no tongue cleaning habit were also investigated. The detection rates of F. nucleatum and C. rectus per total bacteria in smokers were 3.03% and 0.60%, respectively, this correspond to approximately 5 fold the rates detected in non-smokers. The number of F. nucleatum and C. rectus also showed positive correlation coefficients with all volatile sulfur compounds (VSC) values. Conclusions: The results of this study suggest that smoking promotes colonization of periodontopathogenic bacteria in tongue coatings and influences oral malodor by increasing the amount of VSC. The Japanese Association of Smoking Control Science 2017 eng journal article VoR 338170 https://tokushima-u.repo.nii.ac.jp/records/2012374 https://doi.org/10.32213/jascs.vol.11.06_1 10.32213/jascs.vol.11.06_1 18833926 禁煙科学 Japanese Journal of Smoking Control Science 11 6 1 9 https://tokushima-u.repo.nii.ac.jp/record/2012374/files/jascs_11_6_1.pdf application/pdf 824 KB 2024-12-13