2026-03-10T02:52:30Z https://tokushima-u.repo.nii.ac.jp/oai

oai:tokushima-u.repo.nii.ac.jp:02012213 2025-06-10T01:24:27Z 1713853213384:1713853295607

Associations between dietary diversity and high sensitive C-reactive protein among Japanese workers : findings of a cross-sectional and longitudinal study 中本, 真理子 ナカモト, マリコ Nakamoto, Mariko 中本 ナカモト Nakamoto 真理子 マリコ Mariko トラミ, コウキ トラミ, コウキ Torami, Koki Bui, Thuy Thi トウジョウ, アユミ トウジョウ, アユミ Tojyo, Ayumi ヤマダ, カナ ヤマダ, カナ Yamada, Kana 中本, 晶子 ナカモト, アキコ Nakamoto, Akiko 中本 ナカモト Nakamoto 晶子 アキコ Akiko 20570948 秦, 明子 ハタ, アキコ Hata, Akiko 秦 ハタ Hata 明子 アキコ Akiko アキ, ナナコ アキ, ナナコ Aki, Nanako 四釜, 洋介 シカマ, ヨウスケ Shikama, Yosuke 四釜 シカマ Shikama 洋介 ヨウスケ Yosuke 坂東, 由記子 バンドウ, ユキコ Bando, Yukiko 市原, 多香子 イチハラ, タカコ Ichihara, Takako 市原 イチハラ Ichihara 多香子 タカコ Takako 南川, 貴子 ミナガワ, タカコ Minagawa, Takako 南川 ミナガワ Minagawa 貴子 タカコ Takako 田村, 綾子 タムラ, アヤコ Tamura, Ayako 田村 タムラ Tamura 綾子 アヤコ Ayako 桑村, 由美 クワムラ, ユミ Kuwamura, Yumi 桑村 クワムラ Kuwamura 由美 ユミ Yumi 船木, 真理 フナキ, マコト Funaki, Makoto 船木 フナキ Funaki 真理 マコト Makoto 酒井, 徹 サカイ, トオル Sakai, Tohru 酒井 サカイ Sakai 徹 トオル Tohru open access Dietary diversity Inflammatory High sensitive C-reactive protein Japanese worker Cross-sectional study Longitudinal study Purpose: To clarify the association between dietary diversity and inflammatory status in Japanese workers. Methods: Of 1,460 men and women aged 20–64 years in 2010 (baseline), those who were followed-up at least once between 2011 and 2018 were included in this study; 1,433 participants and 745 participants were included in the cross-sectional and longitudinal analyses, respectively. Dietary intake was assessed using a food frequency questionnaire at baseline, and the dietary diversity score was determined using the Quantitative Index for Dietary Diversity (QUANTIDD). High-sensitivity C-reactive protein (hs-CRP) was taken to indicate inflammatory status at the baseline and follow-up surveys. In the cross-sectional analysis using baseline data, a generalized linear model was used to calculate adjusted means and 95% confidence intervals (CIs) for hs-CRP according to the QUANTIDD score. In the longitudinal analysis, generalized estimating equations were used to calculate the adjusted mean (95% CI) for hs-CRP in follow-up according to the QUANTIDD score at baseline. Results: In the cross-sectional analysis, the hs-CRP concentration in male participants was significantly lower in those who had a high QUANTIDD score (adjusted mean [95% CI]: 0.074 [0.009—0.140] mg/dL in the lower group vs. 0.038 [-0.029—0.105] mg/dL in the higher group, p-value=0.034). In the longitudinal analysis, the hs-CRP concentration of male participants also tended to be lower in those with higher QUANTIDD scores (p-value=0.103). In both the cross-sectional and longitudinal analyses in women, there was no significant difference between the lower and higher QUANTIDD score groups. Conclusion: These findings suggest that, in male Japanese workers, higher dietary diversity might be important for maintaining a low inflammatory status. Springer Nature 2024-05-23 eng journal article AM 410206 https://tokushima-u.repo.nii.ac.jp/records/2012213 https://doi.org/10.1007/s00394-024-03389-9 10.1007/s00394-024-03389-9 14366215 14366207 AA11323696 European Journal of Nutrition 63 5 1915 1927 https://tokushima-u.repo.nii.ac.jp/record/2012213/files/ejn_63_5_1915.pdf application/pdf 785 KB 2025-05-23