2026-03-15T20:59:28Z https://tokushima-u.repo.nii.ac.jp/oai

oai:tokushima-u.repo.nii.ac.jp:02006954 2025-06-30T02:34:18Z 1713853213384:1713853296295:1716267876683:1716268551628

先天性心疾患の小児における光干渉断層撮影法を用いた肺動脈壁厚と肺循環動態の関連についての検討 PA Thickening on OCT in Children With CHD Pulmonary Artery Wall Thickness Assessed by Optical Coherence Tomography Correlates With Pulmonary Hemodynamics in Children With Congenital Heart Disease 本間, 友佳子 968 ホンマ, ユカコ 350228/profile-ja.html Honma, Yukako 早渕, 康信 195 ハヤブチ, ヤスノブ 122001/profile-ja.html Hayabuchi, Yasunobu 20403686 オノ, アケミ オノ, アケミ Ono, Akemi 香美, 祥二 1631 カガミ, ショウジ 60248/profile-ja.html Kagami, Shoji 00224337 Children Congenital heart disease Optical coherence tomography Pulmonary arterial hypertension Background: Pulmonary arterial (PA) wall thickening evaluated by optical coherence tomography (OCT) has been reported in adults with PA hypertension. The purpose of this study was to evaluate the feasibility of OCT for preoperative assessment of the PA wall in children with congenital heart disease (CHD). Methods and Results: Participants comprised 39 patients with ventricular septal defect, atrial septal defect, or patent ductus arteriosus. Attempts were made to evaluate vessels of various diameters using OCT. Clearly observed vessels that were optimal for evaluation were selected and classified into 4 subgroups by diameter of the lumen. Optimal depiction was obtained in 80 of 156 vessels in total, and 25 (64.1%), 34 (87.1%), 17 (43.6%), and 4 vessels (10.3%) in each of the 1.0–<2.0 mm, 2.0–<3.0 mm, 3.0–<4.0 mm, and 4.0–5.0 mm subgroups, respectively. Arterial walls in the 2.0–<3.0 mm subgroup were the most frequently delineated, and wall thickness correlated significantly with mean PA pressure, pulmonary vascular resistance index, pulmonary-to-systemic flow ratio, and PA capacitance index (r=0.56, 0.52, 0.37, and −0.49, respectively). The 3-layered appearance was delineated in 29 of 80 vessels (36.2%). This feature had no significant correlation with pulmonary hemodynamics. Conclusions: OCT represents a promising tool for evaluating the PA wall in children with CHD. doctoral thesis The Japanese Circulation Society 2018-08-24 NA application/pdf application/pdf Circulation Journal 9 82 2350 2357 13469843 13474820 AA11591968 https://tokushima-u.repo.nii.ac.jp/record/2006954/files/k3498_abstract_review.pdf https://tokushima-u.repo.nii.ac.jp/record/2006954/files/k3498_fulltext.pdf https://tokushima-u.repo.nii.ac.jp/records/2006954 eng