2026-03-05T07:54:39Z https://tokushima-u.repo.nii.ac.jp/oai

oai:tokushima-u.repo.nii.ac.jp:02008946 2025-04-28T06:45:44Z 1713829974766:1713854681789:1716364513618:1716365191599 1713853213384:1713853295607

A reduced brain and liver FDG uptake A reduced physiological 18F-fluorodeoxyglucose uptake in the brain and liver caused by malignant lymphoma being deprived of the tracer 音見, 暢一 436 オトミ, ヨウイチ 207541/profile-ja.html Otomi, Youichi 50624110 大塚, 秀樹 1642 オオツカ, ヒデキ 60298/profile-ja.html Otsuka, Hideki 30346605 ショウノ, ナホミ ショウノ, ナホミ Shono, Nahomi オオニシ, ハジメ オオニシ, ハジメ Onishi, Hajime 三橋, 遼太 1388 ミツハシ, リヨウタ 406026/profile-ja.html Mitsuhashi, Ryota マツザキ, サヤ マツザキ, サヤ Matsuzaki, Saya 高岡, 友紀子 1465 タカオカ, ユキコ 383346/profile-ja.html Takaoka, Yukiko 榎本, 英明 エノモト, ヒデアキ Enomoto, Hideaki サカモト, ユウコ サカモト, ユウコ Sakamoto, Yuko ササハラ, ミホコ ササハラ, ミホコ Sasahara, Mihoko 阿部, 考志 576 アベ, タカシ 40645347 Abe, Takashi 新家, 崇義 803 シンヤ, タカヨシ 294296/profile-ja.html Shinya, Takayoshi 20444656 原田, 雅史 1589 ハラダ, マサフミ 60159/profile-ja.html Harada, Masafumi 20228654 brain liver malignant lymphoma Purpose : To investigate whether or not the physiological brain and liver FDG uptake are decreased in patients with highly accelerated glycolysis lesions. Methods : We retrospectively analyzed 51 patients with malignant lymphoma. We compared the FDG uptake in the brain and liver of the patients with that in a control group. In 24 patients with a complete response (CR) or partial response (PR) to treatment, we compared the brain and liver uptake before and after treatment. Results : The maximum standardized uptake value (SUVmax) and total glycolytic volume (TGV) of the brain as well as the SUVmax and mean standardized uptake value (SUVmean) of the liver in malignant lymphoma patients were 13.1 ± 2.3, 7386.3 ± 1918.4, 3.2 ± 0.5, and 2.3 ± 0.4, respectively ; in the control group, these values were 14.9 ± 2.4, 8566.2 ± 1659.5, 3.4 ± 0.4, and 2.5 ± 0.3, respectively. The SUVmax and TGV of the brain and the SUVmean of the liver in malignant lymphoma patients were significantly lower than the control group. The SUVmax and TGV of the brain after treatment were significantly higher than before treatment. Both the SUVmax and SUVmean of liver after treatment were higher than before treatment, but not significant. Conclusion : A decreased physiological brain and liver FDG uptake is caused by highly accelerated lesion glycolysis. journal article Tokushima University Faculty of Medicine 2021-02 VoR application/pdf The Journal of Medical Investigation 1-2 68 181 185 13496867 13431420 AA11166929 https://tokushima-u.repo.nii.ac.jp/record/2008946/files/jmi_68_1-2_181.pdf https://tokushima-u.repo.nii.ac.jp/records/2008946 eng