2026-03-09T08:58:59Z https://tokushima-u.repo.nii.ac.jp/oai

oai:tokushima-u.repo.nii.ac.jp:02010034 2025-08-27T04:02:51Z 1713853213384:1713853295607

Claw sign predicts first-pass effect in MT The claw sign predicts first-pass effect in mechanical thrombectomy for cerebral large vessel occlusion in the anterior circulation 山本, 雄貴 1427 ヤマモト, ユウキ 375081/profile-ja.html Yamamoto, Yuki 山本, 伸昭 705 ヤマモト, ノブアキ 277666/profile-ja.html Yamamoto, Nobuaki 兼松, 康久 1217 カネマツ, ヤスヒサ 90363142 Kanematsu, Yasuhisa 山口, 泉 1185 ヤマグチ, イヅミ 70780005 Yamaguchi, Izumi 366331/profile-ja.html 石原, 学 1166 イシハラ, マナブ 364654/profile-ja.html Ishihara, Manabu 宮本, 健志 837 ミヤモト, タケシ 312493/profile-ja.html Miyamoto, Takeshi 曽我部, 周 ソガベ, シュウ Sogabe, Shu 島田, 健司 545 シマダ, ケンジ 241625/profile-ja.html Shimada, Kenji 髙木, 康志 897 タカギ, ヤスシ 334002/profile-ja.html Takagi, Yasushi 和泉, 唯信 1623 イズミ, ユイシン 60227/profile-ja.html Izumi, Yuishin 10335812 Acute ischemic stroke Angiography Claw sign First pass Mechanical thrombectomy Background: Mechanical thrombectomy (MT) is an effective treatment for acute cerebral large vessel occlusion (LVO). Complete recanalization of vessels in a single procedure is defined as the first-pass effect (FPE) and is associated with good prognosis. In this study, angiographic clot protruding sign termed the “claw sign,” was examined as candidate preoperative imaging factor for predicting the FPE. Methods: We retrospectively analyzed data from 91 consecutive patients treated for acute LVO in the anterior circulation by MT between January 2014 and December 2019. The claw sign was defined as a thrombus that protruded proximally by more than half of the diameter of the parent artery. Radiological findings such as claw sign, clinical and etiological features, and outcomes were compared between groups with and without successful FPE. Multivariate analysis was conducted to evaluate perioperative factors associated with FPE. Results: FPE was achieved in 26 of 91 (28.6%) patients and the claw sign was observed in 34 of 91 (37.4%) patients. The claw sign was significantly more frequent in the successful FPE group than in the failed FPE group (53.8% vs. 30.8%; P = 0.040). After the multivariate analysis, the claw sign was the only pretreatment parameter that could predict FPE (odds ratio, 2.67; 95% confidence interval, 1.01–7.06; P = 0.047). Conclusion: The claw sign is an angiographic imaging factor that might predict FPE after MT for anterior circulation acute ischemic stroke. journal article Surgical Neurology International Scientific Scholar 2022-02-25 VoR application/pdf Surgical Neurology International 13 72 https://tokushima-u.repo.nii.ac.jp/record/2010034/files/sni_13_72.pdf https://tokushima-u.repo.nii.ac.jp/records/2010034 eng This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 Licens, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.