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日本人勤労者における食事多様性と脂質異常症との関連 : 横断および縦断解析による検証 Associations between dietary diversity and dyslipidemia among Japanese workers : cross-sectional study and longitudinal study findings Bui, Thi Thuy ブイ, ティ テュイ 中本, 真理子 782 ナカモト, マリコ 293911/profile-ja.html Nakamoto, Mariko 40722533 ヤマダ, カナ ヤマダ, カナ Yamada, Kana 中本, 晶子 863 ナカモト, アキコ 323760/profile-ja.html Nakamoto, Akiko 90803536 秦, 明子 738 ハタ, アキコ 20570948 Hata, Akiko 288515/profile-ja.html アキ, ナナコ アキ, ナナコ Aki, Nanako 四釜, 洋介 455 シカマ, ヨウスケ 10588908 Shikama, Yosuke 坂東, 由記子 バンドウ, ユキコ Bando, Yukiko 市原, 多香子 1602 イチハラ, タカコ 10274268 Ichihara, Takako 南川, 貴子 1615 ミナガワ, タカコ 20314883 Minagawa, Takako 田村, 綾子 1599 タムラ, アヤコ 60171/profile-ja.html Tamura, Ayako 10227275 桑村, 由美 1611 クワムラ, ユミ 60199/profile-ja.html Kuwamura, Yumi 90284322 船木, 真理 337 フナキ, マコト 175544/profile-ja.html Funaki, Makoto 10467821 酒井, 徹 1196 サカイ, トオル 60693/profile-ja.html Sakai, Tohru 40274196 Cross-sectional study Dietary diversity Dyslipidemia Japanese workers Longitudinal study Objective: The aim of this study was to determine the associations between dietary diversity and risk of dyslipidemia in Japanese workers. Methods: The cross-sectional study included 1,399 participants aged 20-63 years and the longitudinal study included 751 participants aged 20 to 60 years in 2012-2013 (baseline) who participated at least once from 2013 to 2017 with cumulative participation times of 4.9 times. Dietary intake was assessed using a food frequency questionnaire, and dietary diversity score (DDS) was determined using the Quantitative Index for Dietary Diversity. Dyslipidemia was diagnosed when at least one of the following conditions was met: hypertriglyceridemia, high LDL-cholesterol, low HDL-cholesterol, high non-HDL-cholesterol, and a history of dyslipidemia. Multivariable logistic regression was used to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) for dyslipidemia with control of confounding factors in cross-sectional analysis. Generalized estimating equations were used for calculating the ORs (95% CI) for dyslipidemia in the follow-up period according to the DDS at baseline with control of confounding factors in longitudinal analysis. Results: Cross-sectional analysis showed that the highest DDS reduced the odds of dyslipidemia in men (OR [95% CI] in Tertile 3: 0.67 [0.48-0.95], p-value= 0.023). In longitudinal analysis, a moderate DDS reduced the risk of dyslipidemia (OR [95% CI] in Tertile 2: 0.21 [0.07-0.60], p-value= 0.003) in women. Conclusions: The results of cross-sectional analysis in this study suggest that the higher diversity of diet might reduce the presence of dyslipidemia in men and the results of longitudinal analysis suggest that a moderate DDS might reduce the risk of dyslipidemia in women. Further studies are needed since the results of cross-sectional and longitudinal analyses in this study were inconsistent. doctoral thesis Springer Nature 2024-05-04 NA application/pdf application/pdf application/pdf European Journal of Nutrition 6 63 2109 2120 14366215 14366207 AA11323696 https://tokushima-u.repo.nii.ac.jp/record/2012214/files/k3880_abstract.pdf https://tokushima-u.repo.nii.ac.jp/record/2012214/files/k3880_review.pdf https://tokushima-u.repo.nii.ac.jp/record/2012214/files/k3880_fulltext.pdf https://tokushima-u.repo.nii.ac.jp/records/2012214 eng