{"created":"2024-10-01T02:39:02.625882+00:00","id":2000264,"links":{},"metadata":{"_buckets":{"deposit":"47e186e3-697a-42d2-9e22-c152bec1b9d4"},"_deposit":{"created_by":51,"id":"2000264","owner":"51","owners":[51],"pid":{"revision_id":0,"type":"depid","value":"2000264"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02000264","sets":["1713853213384:1713853295607"]},"author_link":["228","1496"],"control_number":"2000264","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-08-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageStart":"ofad414","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"Open Forum Infectious Diseases","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background. Eosinophilic pneumonia (EP) is a rare adverse event caused by several types of drugs, such as antibiotics; however, its characteristics remain poorly described. This study aimed to analyze the disproportionality between the occurrence of EP and anti–methicillin-resistant Staphylococcus aureus (anti-MRSA) agents and to characterize anti-MRSA agent–induced EP events using the Food and Drug Administration Adverse Event Reporting System (FAERS).\nMethod. Disproportionality linking EP and anti-MRSA agents was analyzed through bayesian confidence propagation neural networks of information components and reporting odds ratio methodologies. The FAERS data set for the fourth quarter of 2012 to the fourth quarter of 2022 was used. We also analyzed the characteristics of EP induced by anti-MRSA agents.\nResults. A total of 14 805 795 reports were obtained from FAERS. Disproportionality analysis revealed that the EP signal was detected only in cases with the administration of daptomycin (DAP). This disproportionality signal was consistently detected in the sensitivity analysis. When compared with other reports of DAP-related adverse events, the reports of DAP-related EP were characterized by male sex (odds ratio [OR], 1.94; 95% CI, 1.12–3.37), older age (>70 years; OR, 2.70; 95% CI, 1.68–4.33), and longer duration of treatment (>21 days; OR, 5.08; 95% CI, 3.21–8.05).\nConclusions. This study revealed that among the anti-MRSA agents, disproportionality in the occurrence of EP was observed only with DAP. Our results suggest that sex, age, and treatment duration may affect the occurrence of DAP-induced EP. Clinicians should exercise caution regarding EP during DAP administration.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Oxford University Press","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"Creative Commons Attribution-NonCommercial-NoDerivs licence, which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"23288957","subitem_source_identifier_type":"EISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1093/ofid/ofad414"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1093/ofid/ofad414","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"406563"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Okada, Naoto","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"新村, 貴博","creatorNameLang":"ja"},{"creatorName":"ニイムラ, タカヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Niimura, Takahiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"新村","familyNameLang":"ja"},{"familyName":"ニイムラ","familyNameLang":"ja-Kana"},{"familyName":"Niimura","familyNameLang":"en"}],"givenNames":[{"givenName":"貴博","givenNameLang":"ja"},{"givenName":"タカヒロ","givenNameLang":"ja-Kana"},{"givenName":"Takahiro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1496","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"385258/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/385258/profile-ja.html"},{"nameIdentifier":"50910014","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=50910014"}]},{"creatorNames":[{"creatorName":"Saisyo, Atsuyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kawaguchi, Yoshitaka","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"石澤, 啓介","creatorNameLang":"ja"},{"creatorName":"イシザワ, ケイスケ","creatorNameLang":"ja-Kana"},{"creatorName":"Ishizawa, Keisuke","creatorNameLang":"en"}],"familyNames":[{"familyName":"石澤","familyNameLang":"ja"},{"familyName":"イシザワ","familyNameLang":"ja-Kana"},{"familyName":"Ishizawa","familyNameLang":"en"}],"givenNames":[{"givenName":"啓介","givenNameLang":"ja"},{"givenName":"ケイスケ","givenNameLang":"ja-Kana"},{"givenName":"Keisuke","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"228","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"141809/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/141809/profile-ja.html"},{"nameIdentifier":"60398013","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=60398013"}]},{"creatorNames":[{"creatorName":"Kitahara, Takashi","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-10-11"}],"displaytype":"detail","filename":"ofid_10_8_ofad414.pdf","filesize":[{"value":"709 KB"}],"format":"application/pdf","licensetype":"license_5","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2000264/files/ofid_10_8_ofad414.pdf"},"version_id":"ee9022dc-2697-4a20-9b36-f6646659283c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Adverse Event Reporting System","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"daptomycin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"eosinophilic pneumonia","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Pharmacovigilance Study on Eosinophilic Pneumonia  Induced by Anti-MRSA Agents : Analysis Based on the FDA  Adverse Event Reporting System","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Pharmacovigilance Study on Eosinophilic Pneumonia  Induced by Anti-MRSA Agents : Analysis Based on the FDA  Adverse Event Reporting System","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"51","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-11-11"},"publish_date":"2024-11-11","publish_status":"0","recid":"2000264","relation_version_is_last":true,"title":["Pharmacovigilance Study on Eosinophilic Pneumonia  Induced by Anti-MRSA Agents : Analysis Based on the FDA  Adverse Event Reporting System"],"weko_creator_id":"51","weko_shared_id":-1},"updated":"2025-02-03T05:37:29.504256+00:00"}