{"created":"2024-10-09T10:21:36.635266+00:00","id":2000989,"links":{},"metadata":{"_buckets":{"deposit":"c7570a78-31df-428a-bd08-c342a7e816a1"},"_deposit":{"created_by":7,"id":"2000989","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2000989"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02000989","sets":["1713829974766:1713854681789:1716364520696:1716421607488","1713853213384:1713853295607"]},"author_link":["1648"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3-4","bibliographicPageEnd":"117","bibliographicPageStart":"108","bibliographicVolumeNumber":"47","bibliographic_titles":[{"bibliographic_title":"The journal of medical investigation : JMI","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by the combined occurrence of parathyroid, pancreatic endocrine, and anterior pituitary tumors. MEN1 has two characteristics ; a hormone excess and a sometimes lethal outcome due to malignant tumors. The recent identification of the MEN1 gene has opened the door to a much deeper understanding of this syndrome. Germline MEN1 mutations have been identified in most MEN1 families. They were not found, however, in families with familial pituitary tumors. Thus, studies with the MEN1 gene helped to establish that mutation of some other gene(s) is likely causative of the MEN1 phenocopy. These recent advances provide for the identification of mutant MEN1 gene carriers who are at a high risk of developing MEN1. The protein encoded by the MEN1 gene has been shown to function in the regulation of JunD-activated transcription but much still remains to be elucidated.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"13431420","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11166929","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1718868208704":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"データ元 : http://medical.med.tokushima-u.ac.jp/jmi/"}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"71712"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"吉本, 勝彦","creatorNameLang":"ja"},{"creatorName":"ヨシモト, カツヒコ","creatorNameLang":"ja-Kana"},{"creatorName":"Yoshimoto, Katsuhiko","creatorNameLang":"en"}],"familyNames":[{"familyName":"吉本","familyNameLang":"ja"},{"familyName":"ヨシモト","familyNameLang":"ja-Kana"},{"familyName":"Yoshimoto","familyNameLang":"en"}],"givenNames":[{"givenName":"勝彦","givenNameLang":"ja"},{"givenName":"カツヒコ","givenNameLang":"ja-Kana"},{"givenName":"Katsuhiko","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1648","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60308/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/60308/profile-ja.html"},{"nameIdentifier":"90201863","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=90201863"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2011-11-24"}],"displaytype":"detail","filename":"LID201111242004.pdf","filesize":[{"value":"202 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2000989/files/LID201111242004.pdf"},"version_id":"fd9e6b61-c962-460a-af05-81b47ec1e4c3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"MEN1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"menin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pituitary tumors","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"parathyroid tumors","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pancreatic endocrine tumors","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Multiple Endocrine Neoplasia Type 1: From Bedside to Benchside","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Multiple Endocrine Neoplasia Type 1: From Bedside to Benchside","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607","1716421607488"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-11-24"},"publish_date":"2011-11-24","publish_status":"0","recid":"2000989","relation_version_is_last":true,"title":["Multiple Endocrine Neoplasia Type 1: From Bedside to Benchside"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-01-29T01:09:59.137657+00:00"}