{"created":"2024-10-15T12:16:22.056468+00:00","id":2001198,"links":{},"metadata":{"_buckets":{"deposit":"e2c07aba-8025-42cc-9407-2e4dfbbe9c70"},"_deposit":{"created_by":7,"id":"2001198","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2001198"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02001198","sets":["1713829974766:1713854681789:1716364517402:1716365710842","1713853213384:1713853295607"]},"author_link":["1594","385","1604","246"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"94","bibliographicPageStart":"89","bibliographicVolumeNumber":"57","bibliographic_titles":[{"bibliographic_title":"The journal of medical investigation : JMI","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We examined a series of site-directed point mutants of human immunodeficiency virus type 1 (HIV-1) Vif for their interaction with cellular anti-viral factors APOBEC3G/APOBEC3F. Mutant viruses that display growth-defect in H9 cells did not counteract effectively APOBEC3G and/or APOBEC3F without exception, as monitored by single-cycle infectivity assays. While growth-defective mutants of Vif C-terminal region were unable to suppress APOBEC3G/APOBEC3F, some N-terminal region mutants did neutralize one of APOBEC3G/APOBEC3F. These data have suggested that members of APOBEC3 family other than APOBEC3G/APOBEC3F are not important for anti-HIV-1 activity. Furthermore, APOPEC3G/APOBEC3F were found to differently associate with Vif in virions as analyzed by equilibrium density centrifugation. Taken together, these results indicated that interaction of HIV-1 Vif and APOBEC3G is distinct from that between Vif and APOBEC3F.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"13431420","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11166929","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1718868208704":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"The journal of medical investigation : http://medical.med.tokushima-u.ac.jp/jmi/index.html"}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"224122"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ナガオ, タミコ","creatorNameLang":"ja"},{"creatorName":"ナガオ, タミコ","creatorNameLang":"ja-Kana"},{"creatorName":"Nagao, Tamiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ヤマシタ, トモキ","creatorNameLang":"ja"},{"creatorName":"ヤマシタ, トモキ","creatorNameLang":"ja-Kana"},{"creatorName":"Yamashita, Tomoki","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"三宅, 在子","creatorNameLang":"ja"},{"creatorName":"ミヤケ, 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