{"created":"2024-10-25T07:29:17.916853+00:00","id":2002663,"links":{},"metadata":{"_buckets":{"deposit":"693cd6cc-4e4d-4526-acd7-f7ffa9562c27"},"_deposit":{"created_by":7,"id":"2002663","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2002663"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02002663","sets":["1713853213384:1713853296295:1716267777405:1716268540895"]},"author_link":["1657","263","1663"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"遠赤外線エネルギーを放射するセラミックス（流紋岩）は骨形成を促進する","subitem_alternative_title_language":"ja"},{"subitem_alternative_title":"FIR Ceramics Promote the Formation of Bone","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-10-21","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"434","bibliographicPageStart":"423","bibliographicVolumeNumber":"23","bibliographic_titles":[{"bibliographic_title":"Journal of Hard Tissue Biology","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Far infrared ray (FIR) energy radiated by the natural ceramics (Rhyolite) cooled FIR ceramics activates water molecules and blood circulation to stimulate skin and other tissues. The aim of our study is to make clear whether the FIR ceramics radiating FIR energy affect or not on the new bone formation in vivo and in vitro. Methods: MC3T3-E1 cells were cultured in FIR CO2 incubator. The cell proliferation and the gene expression were analyzed by using WST-8 assay kit, RT-PCR and micro array analysis. The enzyme activities were analyzed by using the apiRZYM kit. Furthermore, titanium and natural FIR ceramics compounds were implanted under the periosteium of rat skull bone by injection method. Four weeks later, the samples were examined by the light microscope and micro CT analyses. Results: Proliferation of MC3T3-E1 cell was and DNA concentrations were inhibited by FIR energy radiation. The ALP activities were accelerated and the area of calcification nodules increased on 4 weeks. The RT-PCR data showed that the gene Runx2, Osterix, BSP, OCN, Col1a1 and OPN expression of MC3T3-E1 osteoblast like cells was activated. Bone mineral density (BMD mg/cm²) of implanted sites of T50-F50, T25-F75 and F100 groups was significantly enhanced after 4 weeks compared with control groups. This data shows FIR energy radiation by the natural FIR ceramics promoted bone-forming activity of osteoblasts. Significance: This study suggested that new bioactive ceramics such us natural FIR ceramics was useful for some clinically applications to repair bone defects for example of dental implant surgery.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"THE SOCIETY FOR HARD TISSUE REGENERATIVE BIOLOGY","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© 2014 The Hard Tissue Biology Network Association","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"1880828X","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"13417649","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11074332","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA11653227","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_1714461018643":{"attribute_name":"報告番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第2808号"}]},"item_1714461102074":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（学術）","subitem_degreename_language":"ja"}]},"item_1714461118377":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2015-03-23"}]},"item_1714461137393":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"徳島大学"}]}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1718868208704":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"内容要旨・審査要旨・論文本文の公開:\n内容要旨 : LID201506091002.pdf\n審査要旨 : LID201506091003.pdf\n論文本文 : LID201506091004.pdf\n本論文は, 著者Aldartsogt Dolgorsurenの学位論文として提出され, 学位審査・授与の対象となっている。\n学位授与者所属 : 徳島大学大学院口腔科学教育部（口腔科学専攻）"}]},"item_1718868303842":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"甲口第390号"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.2485/jhtb.23.423"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2485/jhtb.23.423","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"287591"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ドルゴルスレン, アルダルツォグト","creatorNameLang":"ja"},{"creatorName":"ドルゴルスレン, アルダルツォグト","creatorNameLang":"ja-Kana"},{"creatorName":"Dolgorsuren, Aldartsogt","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"山下, 菊治","creatorNameLang":"ja"},{"creatorName":"ヤマシタ, キクジ","creatorNameLang":"ja-Kana"},{"creatorName":"Yamashita, Kikuji","creatorNameLang":"en"}],"familyNames":[{"familyName":"山下","familyNameLang":"ja"},{"familyName":"ヤマシタ","familyNameLang":"ja-Kana"},{"familyName":"Yamashita","familyNameLang":"en"}],"givenNames":[{"givenName":"菊治","givenNameLang":"ja"},{"givenName":"キクジ","givenNameLang":"ja-Kana"},{"givenName":"Kikuji","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1663","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30182497","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=30182497"}]},{"creatorNames":[{"creatorName":"Dalkhsuren, Shine-Od","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"角田, 佳折","creatorNameLang":"ja"},{"creatorName":"スミダ, カオリ","creatorNameLang":"ja-Kana"},{"creatorName":"Sumida, Kaori","creatorNameLang":"en"}],"familyNames":[{"familyName":"角田","familyNameLang":"ja"},{"familyName":"スミダ","familyNameLang":"ja-Kana"},{"familyName":"Sumida","familyNameLang":"en"}],"givenNames":[{"givenName":"佳折","givenNameLang":"ja"},{"givenName":"カオリ","givenNameLang":"ja-Kana"},{"givenName":"Kaori","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"263","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"157326/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/157326/profile-ja.html"}]},{"creatorNames":[{"creatorName":"関, 伸一郎","creatorNameLang":"ja"},{"creatorName":"セキ, シンイチロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Seki, Shinichiro","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"北村, 清一郎","creatorNameLang":"ja"},{"creatorName":"キタムラ, セイイチロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Kitamura, Seiichiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"北村","familyNameLang":"ja"},{"familyName":"キタムラ","familyNameLang":"ja-Kana"},{"familyName":"Kitamura","familyNameLang":"en"}],"givenNames":[{"givenName":"清一郎","givenNameLang":"ja"},{"givenName":"セイイチロウ","givenNameLang":"ja-Kana"},{"givenName":"Seiichiro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1657","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60319/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/60319/profile-ja.html"},{"nameIdentifier":"30093404","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=30093404"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2015-06-10"}],"displaytype":"detail","filename":"LID201506091002.pdf","filesize":[{"value":"67.8 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"abstract","url":"https://tokushima-u.repo.nii.ac.jp/record/2002663/files/LID201506091002.pdf"},"version_id":"f8235823-af1f-4e66-b56f-5c825e0ef0b1"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2015-06-10"}],"displaytype":"detail","filename":"LID201506091003.pdf","filesize":[{"value":"410 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"other","url":"https://tokushima-u.repo.nii.ac.jp/record/2002663/files/LID201506091003.pdf"},"version_id":"c94c1470-21e6-4082-b817-324eff8ce88f"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2015-06-10"}],"displaytype":"detail","filename":"LID201506091004.pdf","filesize":[{"value":"10.1 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2002663/files/LID201506091004.pdf"},"version_id":"8ea73e28-7292-4b73-af40-313004bcdb2b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Bone formation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Far-infrared ray","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Osteoblast","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"The Ceramics Radiating Far Infrared Ray Energy (Rhyolite) Promote the Formation of Bone","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The Ceramics Radiating Far Infrared Ray Energy (Rhyolite) Promote the Formation of Bone","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1716268540895"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-06-09"},"publish_date":"2015-06-09","publish_status":"0","recid":"2002663","relation_version_is_last":true,"title":["The Ceramics Radiating Far Infrared Ray Energy (Rhyolite) Promote the Formation of Bone"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-01-29T06:06:28.737862+00:00"}