{"created":"2024-10-25T07:39:12.632714+00:00","id":2002798,"links":{},"metadata":{"_buckets":{"deposit":"734b0c05-f325-42ee-b2af-8e5e5c8b3e65"},"_deposit":{"created_by":7,"id":"2002798","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2002798"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02002798","sets":["1713829974766:1713854681789:1716364516170:1716365540255","1713853213384:1713853295607"]},"author_link":["1535","1253","1578","1274"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"189","bibliographicPageStart":"180","bibliographicVolumeNumber":"61","bibliographic_titles":[{"bibliographic_title":"The journal of medical investigation : JMI","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Glucose intolerance characterized by postprandial hyperglycemia and hyperinsulinemia\nis commonly seen in patients with liver cirrhosis (LC). The aim of this study\nis to clarify the relation between glucose intolerance and disorder of liver function in\npatients with LC. The 75 g oral glucose tolerance test (75 g OGTT) and the hyperinsulinemic\neuglycemic clamp combined with 0.2 g/kg oral glucose load (HECGL) were conducted\nin 61 patients with LC. Based on the results of 75 g OGTT, the 61 patientswith LCwere divided\ninto groups, 21 (34.4%) patients with normal glucose tolerance (LC-NGT), 12 (19.7%)\npatients with impaired glucose tolerance (LC-IGT) and 28 (45.9%) patients with diabetes\nmellitus (LC-DM). Fasting plasma glucose (FPG) level was normal in 50 (82.0%) patients\nwith LC. All patients with LC showed insulin resistance in both peripheral (skeletal and\nadipose) and hepatic tissues evaluated by HECGL, although significant correlation between\nthe degree of glucose intolerance and the severity of hepatic dysfunction was not observed.\nInsulin resistance in both liver and peripheral tissues is the early sign in the patients with\nLC. This fact indicates that nutritional care from early stages of LC would be necessary in\nthe patients.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"13431420","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11166929","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.2152/jmi.61.180"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2152/jmi.61.180","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"284836"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"タグチ, カヨ","creatorNameLang":"ja"},{"creatorName":"タグチ, カヨ","creatorNameLang":"ja-Kana"},{"creatorName":"Taguchi, Kayo","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"(山中)奥村, 仙示","creatorNameLang":"ja"},{"creatorName":"(ヤマナカ)オクムラ, ヒサミ","creatorNameLang":"ja-Kana"},{"creatorName":"Yamanaka-Okumura, 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英二","creatorNameLang":"ja"},{"creatorName":"タケダ, エイジ","creatorNameLang":"ja-Kana"},{"creatorName":"Takeda, Eiji","creatorNameLang":"en"}],"familyNames":[{"familyName":"武田","familyNameLang":"ja"},{"familyName":"タケダ","familyNameLang":"ja-Kana"},{"familyName":"Takeda","familyNameLang":"en"}],"givenNames":[{"givenName":"英二","givenNameLang":"ja"},{"givenName":"エイジ","givenNameLang":"ja-Kana"},{"givenName":"Eiji","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1578","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60131/profile-ja.html","nameIdentifierScheme":"徳島大学 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cirrhosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hyperinsulinemic euglycemic clamp combined with oral glucose load","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"indirect calorimetry","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"diabetes mellitus","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Insulin resistance as early sign of hepatic dysfunction in liver cirrhosis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Insulin resistance as early sign of hepatic dysfunction in liver cirrhosis","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607","1716365540255"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2016-01-28"},"publish_date":"2016-01-28","publish_status":"0","recid":"2002798","relation_version_is_last":true,"title":["Insulin resistance as early sign of hepatic dysfunction in liver cirrhosis"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-14T00:26:50.540754+00:00"}