{"created":"2024-10-25T07:43:14.509636+00:00","id":2002851,"links":{},"metadata":{"_buckets":{"deposit":"6091e762-db92-4de8-9f43-ece519e32bcc"},"_deposit":{"created_by":7,"id":"2002851","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2002851"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02002851","sets":["1713829974766:1713854682253:1716422250563:1716423188724","1713853213384:1713853295607"]},"author_link":["340","564","197","183","1159","305","309"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"Ectopic fat deposition, type 2 diabetes mellitus and cardiovascular diseases","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-04-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"28","bibliographicPageStart":"21","bibliographicVolumeNumber":"69","bibliographic_titles":[{"bibliographic_title":"四国医学雑誌","bibliographic_titleLang":"ja"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"There is evidence supporting the notion that excess abdominal fat is predictive of insulin resistance and the presence of related metabolic abnormalities currently referred to as the metabolic syndrome (MetS). Despite the fact that abdominal obesity is a highly prevalent feature of MetS, the mechanisms by which abdominal obesity is causally related to MetS are not fully elucidated. Besides visceral fat accumulation, ectopic lipid deposition, especially in the liver and skeletal muscle, has been implicated in the pathophysiology of diabetes, insulin resistance and obesity-related disorders. In addition, ectopic fat deposition play a critical role in the heart components such as (1) circulatory and locally recruited fat, (2) intra-and extra-myocellular fat, (3) perivascular fat, and (4) pericardial fat. In this review, the contribution of ectopic lipid deposition to global cardiometabolic risk is discussed via possible mechanisms including adipocytokine, insulin resistance and lipotoxicity.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"徳島医学会","subitem_publisher_language":"ja"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"00373699","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AN00102041","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"281745"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"島袋, 充生","creatorNameLang":"ja"},{"creatorName":"シマブクロ, ミチオ","creatorNameLang":"ja-Kana"},{"creatorName":"Shimabukuro, Michio","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Dagvasumberel, Munkhbaatar","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"石田, 昌義","creatorNameLang":"ja"},{"creatorName":"イシダ, マサヨシ","creatorNameLang":"ja-Kana"},{"creatorName":"Ishida, Masayoshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"松本, 幸子","creatorNameLang":"ja"},{"creatorName":"マツモト, サチコ","creatorNameLang":"ja-Kana"},{"creatorName":"Matsumoto, Sachiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"小塚, 智沙代","creatorNameLang":"ja"},{"creatorName":"コズカ, チサヨ","creatorNameLang":"ja-Kana"},{"creatorName":"Kozuka, Chisayo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"平良, 伸一郎","creatorNameLang":"ja"},{"creatorName":"タイラ, シンイチロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Taira, Shin-ichiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"屋比久, 浩市","creatorNameLang":"ja"},{"creatorName":"ヤビク, コウイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Yabiku, Kouichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"八木, 秀介","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"340","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福田, 大受","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"564","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山田, 博胤","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"197","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"添木, 武","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"183","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"若槻, 哲三","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1159","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"親泊, 政一","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"305","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"益崎, 裕章","creatorNameLang":"ja"},{"creatorName":"マスザキ, ヒロアキ","creatorNameLang":"ja-Kana"},{"creatorName":"Masuzaki, Hiroaki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"佐田, 政隆","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"309","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2016-06-08"}],"displaytype":"detail","filename":"LID201606085004.pdf","filesize":[{"value":"1.77 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2002851/files/LID201606085004.pdf"},"version_id":"a1d2a5c3-b482-4b65-90d5-71782b3e7179"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Ectopic fat deposition","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Diabetes mellitus","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cardiovascular diseases","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Obesity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Metabolic syndrome","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Lipotoxicity","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"異所性脂肪と2型糖尿病・心臓血管病","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"異所性脂肪と2型糖尿病・心臓血管病","subitem_title_language":"ja"},{"subitem_title":"イショセイ シボウ ト 2ガタ トウニョウビョウ シンゾウ ケッカンビョウ","subitem_title_language":"ja-Kana"}]},"item_type_id":"40001","owner":"7","path":["1713853295607","1716423188724"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2016-06-08"},"publish_date":"2016-06-08","publish_status":"0","recid":"2002851","relation_version_is_last":true,"title":["異所性脂肪と2型糖尿病・心臓血管病"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2024-10-28T01:35:10.429274+00:00"}