{"created":"2024-10-25T10:32:38.790995+00:00","id":2003613,"links":{},"metadata":{"_buckets":{"deposit":"719b442d-219e-4ff8-bb71-eedc9ddcca08"},"_deposit":{"created_by":7,"id":"2003613","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2003613"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02003613","sets":["1713829974766:1713854682253:1716422248699:1716422873971","1713853213384:1713853295607"]},"author_link":["1644","400","340","1603"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"Protective effects of anesthetics and perioperative managements on vascular function","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-04-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"58","bibliographicPageStart":"47","bibliographicVolumeNumber":"73","bibliographic_titles":[{"bibliographic_title":"四国医学雑誌","bibliographic_titleLang":"ja"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Potassium channels play an essential role in the membrane potential of arterial smooth muscle, and also in regulating contractile tone. Especially, in vascular smooth muscle, the opening of adenosine triphosphate（ATP）-sensitive potassium（KATP）channels leads to membrane hyperpolarization, resulting in muscle relaxation and vasodilation. This activation also plays a role in tissues during pathophysiologic events such as ischemia, hypoxia, and vasodilatory shock. In this review, we will describe the physiological and pathophysiological roles of vascular smooth muscle KATP channels in relation to the effects of anesthetics and perioperative managements. Although accumulated evidence suggests that many anesthetics and perioperative managements（especially, diabetes and hyperglycemia）modify the above function of K+ channels as a metabolic sensor. Use of effective volatile anesthetics and the strict glycemic control may contribute to protect perioperative vascular function.  ","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"徳島医学会","subitem_publisher_language":"ja"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"00373699","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AN00102041","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"324789"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"川人, 伸次","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1644","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"曽我, 朋宏","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"400","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"八木, 秀介","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"340","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松下, 新悟","creatorNameLang":"ja"},{"creatorName":"マツシタ, シンゴ","creatorNameLang":"ja-Kana"},{"creatorName":"Matsushita, Shingo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"谷, 洋江","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1603","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"増矢, 幸子","creatorNameLang":"ja"},{"creatorName":"マスヤ, サチコ","creatorNameLang":"ja-Kana"},{"creatorName":"Masuya, Sachiko","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2017-11-14"}],"displaytype":"detail","filename":"sam_73_1-2_47.pdf","filesize":[{"value":"1.46 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2003613/files/sam_73_1-2_47.pdf"},"version_id":"491fca96-6019-43cf-ad02-9288436097c4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Vascular function","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Anesthetics","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"KATP channel","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Oxidative stress","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Intensive insulin therapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"周術期の血管機能保護戦略","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"周術期の血管機能保護戦略","subitem_title_language":"ja"},{"subitem_title":"シュウジュツキ ノ ケッカン キノウ ホゴ センリャク","subitem_title_language":"ja-Kana"}]},"item_type_id":"40001","owner":"7","path":["1713853295607","1716422873971"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-11-14"},"publish_date":"2017-11-14","publish_status":"0","recid":"2003613","relation_version_is_last":true,"title":["周術期の血管機能保護戦略"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2024-10-28T01:38:47.020210+00:00"}