{"created":"2024-10-28T02:31:37.839841+00:00","id":2003879,"links":{},"metadata":{"_buckets":{"deposit":"99088802-f117-48e0-ab63-23c81b390170"},"_deposit":{"created_by":7,"id":"2003879","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2003879"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02003879","sets":["1713829974766:1713854681789:1716364519769:1716421476340","1713853213384:1713853295607"]},"author_link":["168","1567"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"94","bibliographicPageStart":"87","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"The journal of medical investigation : JMI","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Human chymase produces not only angiotensin II but also endothelin(ET)-1(1-31). We previously reported that ET-1(1-31) had several biological activities in vascular smooth muscle cells. In this study, we investigated the vasoconstrictor effect of ET-1(1-31) on the renal resistance vessels using in vitro micro perfused rabbit afferent and efferent arterioles.ET-1(1-31) decreased the lumen diameter of the afferent and efferent arterioles dose-dependently.ET-1(1-31)-induced afferent arteriolar vasoconstriction was not affected by phosphoramidon, an ET converting enzyme inhibitor. ET-1(1-31)-induced renal arteriolar vasoconstriction was inhibited by BQ123, an ETA receptor inhibitor, but not by BQ788, an ETB receptor inhibitor. These results suggest that ET-1(1-31)-induced renal arteriolar vasoconstriction may be mediated by ETA-like receptors.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"13431420","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11166929","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"113746"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小澤, 祐一","creatorNameLang":"ja"},{"creatorName":"オザワ, ユウイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Ozawa, Yuichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"長谷川, 豊司","creatorNameLang":"ja"},{"creatorName":"ハセガワ, トヨシ","creatorNameLang":"ja-Kana"},{"creatorName":"Hasegawa, Toyoshi","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"土屋, 浩一郎","creatorNameLang":"ja"},{"creatorName":"ツチヤ, コウイチロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Tsuchiya, 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arteriole","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"efferent arteriole","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effect of endothelin-1 (1-31) on the renal resistance vessels","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effect of endothelin-1 (1-31) on the renal resistance vessels","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607","1716421476340"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-11-21"},"publish_date":"2017-11-21","publish_status":"0","recid":"2003879","relation_version_is_last":true,"title":["Effect of endothelin-1 (1-31) on the renal resistance vessels"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-01-29T03:49:39.435450+00:00"}