| Item type |
文献 / Documents(1) |
| 公開日 |
2018-01-22 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.2152/jmi.55.112 |
|
|
関連名称 |
10.2152/jmi.55.112 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Observations on the occurrence of exacerbations in clinical course of systemic lupus erythematosus |
| 著者 |
冨岡, 麗子
谷, 憲治
佐藤, 恵子
鈴鹿, 千幸
豊田, 優子
岸, 潤
曽根, 三郎
|
| 抄録 |
|
|
内容記述 |
Systemic lupus erythematosus (SLE) is a chronic disease that is characterized by an undulating course of exacerbations and remissions, and a major determinant of long-term prognosis is organ damage consequent to tissue injury that accompanies disease activity and toxicity of therapy. In this study, we evaluated which patients with SLE will develop an exacerbation and whether factors can be identified to predict the development of an exacerbation. Fifty-seven SLE patients (52 females) were included in this study. The exacerbation of SLE was found in 15 patients (26.3%). A relatively increased incidence of an exacerbation was found in younger SLE patients. An increased percentage of patients who had lupus nephritis at the time of diagnosis of SLE was found in patients with a subsequent exacerbation when compared with that in those without it. Increased incidence of an exacerbation was observed in patients who had decreased number of WBC and platelets, decreased level of C3 and CH50, and the presence positivity of anti-Sm antibodies at the time of the diagnosis. This study suggests that age, renal involvement, and the presence of decreased number of WBC and platelets, decreased level of complements anti-Sm antibodies are predictors of exacerbation. |
| キーワード |
|
|
主題 |
systemic lupus erythematosus |
| キーワード |
|
|
主題 |
exacerbation |
| キーワード |
|
|
主題 |
lupus nephritis |
| キーワード |
|
|
主題 |
anti-Sm antibodies |
| 書誌情報 |
en : The journal of medical investigation : JMI
巻 55,
号 1-2,
p. 112-119,
発行日 2008-02
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13431420 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11166929 |
| EID |
|
|
識別子 |
234647 |
| 言語 |
|
|
言語 |
eng |
jmi_55_1-2_112.pdf (668 KB)
