{"created":"2024-10-28T02:47:38.871666+00:00","id":2004087,"links":{},"metadata":{"_buckets":{"deposit":"fa7673df-0c51-445b-93f4-2785bfe91b7a"},"_deposit":{"created_by":7,"id":"2004087","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2004087"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02004087","sets":["1713853213384:1713853295607"]},"author_link":["271","746"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-11-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"230","bibliographicPageStart":"223","bibliographicVolumeNumber":"161","bibliographic_titles":[{"bibliographic_title":"The Journal of Biochemistry","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The G72 gene is one of the most susceptible genes to schizophrenia and is contained exclusively in the genomes of primates. The product of the G72 gene modulates the activity of D-amino acid oxidase (DAO) and is a small protein prone to aggregate, which hampers its structural studies. In addition, lack of a known structure of a homologue makes it difficult to use the homology modeling method for the prediction of the structure. Thus, we first developed a hybrid ab initio approach for small proteins prior to the prediction of the structure of G72. The approach uses three known ab initio algorithms. To evaluate the hybrid approach, we tested our prediction of the structure of the amino acid sequences whose structures were already solved and compared the predicted structures with the experimentally solved structures. Based on these comparisons, the average accuracy of our approach was calculated to be ∼5 Å. We then applied the approach to the sequence of G72 and successfully predicted the structures of the N- and C-terminal domains (ND and CD, respectively) of G72. The predicted structures of ND and CD were similar to membrane-bound proteins and adaptor proteins, respectively.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Oxford University Press","subitem_publisher_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"17562651","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"0021924X","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA12096002","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA00694073","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1718868208704":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"This is a pre-copyedited, author-produced version of an article accepted for publication in The Journal of Biochemistry following peer review. The version of record, The Journal of Biochemistry (2017) Vol.161 Issue.2 p.223-230 is available online at: https://doi.org/10.1093/jb/mvw064."}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1093/jb/mvw064","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"322896"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"加藤, 有介","creatorNameLang":"ja"},{"creatorName":"カトウ, ユウスケ","creatorNameLang":"ja-Kana"},{"creatorName":"Kato, Yusuke","creatorNameLang":"en"}],"familyNames":[{"familyName":"加藤","familyNameLang":"ja"},{"familyName":"カトウ","familyNameLang":"ja-Kana"},{"familyName":"Kato","familyNameLang":"en"}],"givenNames":[{"givenName":"有介","givenNameLang":"ja"},{"givenName":"ユウスケ","givenNameLang":"ja-Kana"},{"givenName":"Yusuke","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"746","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70596816","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=70596816"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"福井, 清","creatorNameLang":"ja"},{"creatorName":"フクイ, キヨシ","creatorNameLang":"ja-Kana"},{"creatorName":"Fukui, Kiyoshi","creatorNameLang":"en"}],"familyNames":[{"familyName":"福井","familyNameLang":"ja"},{"familyName":"フクイ","familyNameLang":"ja-Kana"},{"familyName":"Fukui","familyNameLang":"en"}],"givenNames":[{"givenName":"清","givenNameLang":"ja"},{"givenName":"キヨシ","givenNameLang":"ja-Kana"},{"givenName":"Kiyoshi","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"271","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"15881/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/15881/profile-ja.html"},{"nameIdentifier":"00175564","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=00175564"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2017-11-22"}],"displaytype":"detail","filename":"jb_161_2_223.pdf","filesize":[{"value":"7.64 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2004087/files/jb_161_2_223.pdf"},"version_id":"37ce9d85-0b50-4f43-940e-898b6f4f744d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"G72","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ab initio method","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"structure prediction","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"schizophrenia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"D-amino acid oxidase","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Structure models of G72, the product of a susceptibility gene to schizophrenia","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Structure models of G72, the product of a susceptibility gene to schizophrenia","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-11-22"},"publish_date":"2017-11-22","publish_status":"0","recid":"2004087","relation_version_is_last":true,"title":["Structure models of G72, the product of a susceptibility gene to schizophrenia"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-10T06:31:05.406698+00:00"}