{"created":"2024-10-28T03:10:44.837484+00:00","id":2004370,"links":{},"metadata":{"_buckets":{"deposit":"211f443c-ecba-421d-8a96-e35b9ac5522c"},"_deposit":{"created_by":7,"id":"2004370","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2004370"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02004370","sets":["1713853213384:1713853296295:1716268427747:1716268703682"]},"author_link":["1589","1642","1564","536"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"resting state functional MRIによる自閉性障害若年者におけるdefault mode networkの変化に関する検討","subitem_alternative_title_language":"ja"},{"subitem_alternative_title":"Alteration of default mode network in children with autism spectrum disorder","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3-4","bibliographicPageEnd":"208","bibliographicPageStart":"204","bibliographicVolumeNumber":"63","bibliographic_titles":[{"bibliographic_title":"The Journal of Medical Investigation","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose : The purpose of this study was to investigate changes in the functional connectivity of the default mode network (DMN) in normal aging and in children with autistic spectrum disorder (ASD) by using resting-state functional magnetic resonance imaging (rsfMRI) and independent component analysis. Methods : Thirty-one healthy controls (HC) in four age groups (1-3, 4-8, 20-29, and 50-59 years) and 14 childhood ASD cases (1-8 years of age) were examined by rsfMRI echo-planar imaging on a clinical 3-T MRI scanner. Imaging of all children (1-8 years) was conducted under sedation, while adults were scanned in the awake state with eyes closed. Results : The regions of DMN functional connectivity in the bilateral inferior parietal lobule and posterior cingulate cortex were smaller in HC children than in HC adults, and smaller in the ASD group than in the HC children. Conclusion : It is possible to observe developmental and pathological changes in the DMN by rsfMRI. Reduced DMN functional connectivity in children may be a useful biomarker for ASD diagnosis.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Faculty of Medicine Tokushima University","subitem_publisher_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"13496867","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"13431420","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11166929","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA12022913","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_1714461018643":{"attribute_name":"報告番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第3004号"}]},"item_1714461102074":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（保健学）","subitem_degreename_language":"ja"}]},"item_1714461118377":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2016-12-15"}]},"item_1714461137393":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"徳島大学"}]}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1718868208704":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"内容要旨・審査要旨・論文本文の公開:\n内容要旨 : LID201701261003.pdf\n審査要旨 : LID201701261004.pdf\n論文本文 : LID201701261005.pdf\n本論文は，著者Yasuhiro Funakoshiの学位論文として提出され，学位審査・授与の対象となっている。\n学位授与者所属 : 徳島大学大学院保健科学教育部（保健学専攻）"}]},"item_1718868303842":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"甲保第25号"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.2152/jmi.63.204"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2152/jmi.63.204","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"328028"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"船越, 康宏","creatorNameLang":"ja"},{"creatorName":"フナコシ, ヤスヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Funakoshi, Yasuhiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"原田, 雅史","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1589","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大塚, 秀樹","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1642","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森, 健治","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1564","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤, 弘道","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"536","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"イワナガ, タカシ","creatorNameLang":"ja"},{"creatorName":"イワナガ, タカシ","creatorNameLang":"ja-Kana"},{"creatorName":"Iwanaga, Takashi","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2017-01-26"}],"displaytype":"detail","filename":"LID201701261003.pdf","filesize":[{"value":"197 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cortex","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"development","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Default mode network abnormalities in children with autism spectrum disorder detected by resting-state functional magnetic resonance imaging","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Default mode network abnormalities in children with autism spectrum disorder detected by resting-state functional magnetic resonance imaging","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1716268703682"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-04-23"},"publish_date":"2018-04-23","publish_status":"0","recid":"2004370","relation_version_is_last":true,"title":["Default mode network abnormalities in children with autism spectrum disorder detected by resting-state functional magnetic resonance imaging"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2024-10-28T03:10:56.165902+00:00"}