| Item type |
文献 / Documents(1) |
| 公開日 |
2018-05-22 |
| アクセス権 |
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|
アクセス権 |
open access |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
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|
関連識別子 |
https://doi.org/10.2152/jmi.56.111 |
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|
関連名称 |
10.2152/jmi.56.111 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Efficacy of intravitreal bevacizumab (AvastinTM) for short-term treatment of diabetic macular edema |
| 著者 |
ナガサワ, トシヒコ
内藤, 毅
松下, 新悟
サトウ, ヒロユキ
香留, 崇
塩田, 洋
|
| 抄録 |
|
|
内容記述 |
Purpose : To report the efficacy of intravitreal injections of bevacizumab for diabetic macular edema (DME) in the short-term. Design : Retrospective, noncomparative, interventional case series.Methods : Medical records of 20 eyes of 19 patients who underwent intravitreal injections of bevacizumab for persistent diabetic macular edema were reviewed retrospectively. All eyes received intravitreal injections of bevacizumab (1.25 mg/ 0.05 ml). The clinical course of best-corrected visual acuity (BCVA) using a logarithm of the minimum angle of resolution chart, and averaged foveal retinal thickness using an optical coherence tomography (OCT) were monitored for up to four weeks after the injection. Results : BCVA at one week improved by two lines or more in six eyes (30%) and in nine eyes (45%) at four weeks. However, no significant improvement in the mean BCVA from baseline was observed at one week (P>0.05) and four weeks (P>0.05). Mean retinal thicknesses (RT) were 411±170μm at baseline, 349±102μm at one week after the injection (P<0.05), and 380±159μm at four weeks (P>0.05). One week after the injection, significant regression of macular edema was seen. However, recurrence occurred at four weeks. No complications such as severe vision loss, endophthalmitis, or systemic events developed. Conclusion : No changes in BCVA and RT were observed in the short-term observation after the intravitreal injection of bevacizumab for DME. |
| キーワード |
|
|
主題 |
bevacizumab |
| キーワード |
|
|
主題 |
Avastin |
| キーワード |
|
|
主題 |
diabetic macular edema |
| キーワード |
|
|
主題 |
diabetic retinopathy |
| 書誌情報 |
en : The Journal of Medical Investigation
巻 56,
号 3-4,
p. 111-115,
発行日 2009-08
|
| 収録物ID |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13496867 |
| 収録物ID |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13431420 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11166929 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12022913 |
| 出版者 |
|
|
出版者 |
Faculty of Medicine Tokushima University |
| EID |
|
|
識別子 |
231898 |
| 言語 |
|
|
言語 |
eng |
jmi_56_3-4_111.pdf (502 KB)
