{"created":"2024-10-28T03:29:50.751747+00:00","id":2004619,"links":{},"metadata":{"_buckets":{"deposit":"e6f609e4-6299-4bca-933f-b5580cb58dc8"},"_deposit":{"created_by":7,"id":"2004619","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2004619"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02004619","sets":["1713853213384:1713853296295:1716267876683:1716268551628"]},"author_link":["392","546","1581"],"control_number":"2004619","item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"社会経済的格差のネガティブな認識と抑うつ気分は末梢血白血球のPPBPとSLC1A7 遺伝子の発現を低下させる","subitem_alternative_title_language":"ja"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-06-14","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"1338825","bibliographicVolumeNumber":"4","bibliographic_titles":[{"bibliographic_title":"Cogent Psychology","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Inequality in socioeconomic status (SES) is associated with an increased risk for the development of mental health problems. Here, we examined the association between socioeconomic status (SSS) and psychological distress, and measured gene expression signatures in peripheral blood leukocytes responsible for this association, in 129 healthy adults (27 males and 102 females, aged 44.0 ± 13.0 years) working in a private hospital in Japan. Depressive mood was assessed by Zung Selfrating Depression Scale (SDS). A multiple regression analysis adjusted for gender and age showed that subjective SSS was independently and negatively associated with SDS score. We next focused on 9 subjects who exhibited low SSS scores and 11 subjects with high SSS scores. Microarray analysis revealed that levels of 522 mRNAs were differentially expressed in periheral leukocytes between low and high-SSS groups. The differentially expressed genes were preferentially involved in cellular movement or inflammatory responses. Among them, mRNA levels of pro-platelet basic protein (PPBP) and solute carrier family 1 (glutamine transporter), member 7 (SLC1A7) were negatively correlated with SSS scores. Our results re-confirmed the association between negative perception of SES and depressive mood in healthy adults, and suggest a possible involvement of PPBP and SLC1A7 in the association.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Cogent OA","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© 2017 The Author(s). This open access article is distributed under a Creative Commons Attribution (CC-BY) 4.0 license.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"23311908","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_1714461018643":{"attribute_name":"報告番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第3129号"}]},"item_1714461102074":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_1714461118377":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2018-03-23"}]},"item_1714461137393":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"徳島大学"}]}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1718868208704":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"内容要旨・審査要旨・論文本文の公開\n本論文は, 著者Kinuyo Fujitaの学位論文として提出され, 学位審査・授与の対象となっている。\n学位授与者所属 : 徳島大学大学院医科学教育部（医学専攻）"}]},"item_1718868303842":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"甲医第1363号"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1080/23311908.2017.1338825"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1080/23311908.2017.1338825","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"331435"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"藤田, 絹代","creatorNameLang":"ja"},{"creatorName":"フジタ, キヌヨ","creatorNameLang":"ja-Kana"},{"creatorName":"Fujita, Kinuyo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"桑野, 由紀","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"392","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"サイジョウ, サキ","creatorNameLang":"ja"},{"creatorName":"サイジョウ, サキ","creatorNameLang":"ja-Kana"},{"creatorName":"Saijo, Saki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"西川, 達哉","creatorNameLang":"ja"},{"creatorName":"ニシカワ, タツヤ","creatorNameLang":"ja-Kana"},{"creatorName":"Nishikawa, Tatsuya","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"西田, 憲生","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"546","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"六反, 一仁","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1581","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2018-04-19"}],"displaytype":"detail","filename":"k3129_abstract_review.pdf","filesize":[{"value":"332 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"abstract","url":"https://tokushima-u.repo.nii.ac.jp/record/2004619/files/k3129_abstract_review.pdf"},"version_id":"eb12b90b-9211-45eb-9dc7-58b7beb48f4c"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2018-04-19"}],"displaytype":"detail","filename":"k3129_fulltext.pdf","filesize":[{"value":"1.26 MB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2004619/files/k3129_fulltext.pdf"},"version_id":"8beb2f9e-b88c-45a8-b12e-6eb15d7e17c5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"subjective socioeconomic status","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"depressive mood","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"peripheral blood leukocytes","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gene expression","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"PPBP","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"SLC1A7","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Negative perception of socioeconomic status with depressive mood down-regulates expression of PPBP and SLC1A7 genes in peripheral blood leukocytes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Negative perception of socioeconomic status with depressive mood down-regulates expression of PPBP and SLC1A7 genes in peripheral blood leukocytes","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1716268551628"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-04-19"},"publish_date":"2018-04-19","publish_status":"0","recid":"2004619","relation_version_is_last":true,"title":["Negative perception of socioeconomic status with depressive mood down-regulates expression of PPBP and SLC1A7 genes in peripheral blood leukocytes"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2024-12-13T05:00:38.590081+00:00"}