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Systemic inflammation and family history in relation to the prevalence of type 2 diabetes based on an alternating decision tree
https://tokushima-u.repo.nii.ac.jp/records/2005500
https://tokushima-u.repo.nii.ac.jp/records/20055003392324a-8810-4517-af04-1b6b6d9b54bc
| 名前 / ファイル | ライセンス | アクション |
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srep_7_45502.pdf (693 KB)
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| Item type | 文献 / Documents(1) | |||||||||||||||||||||||||
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| 公開日 | 2018-11-12 | |||||||||||||||||||||||||
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| アクセス権 | open access | |||||||||||||||||||||||||
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| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||||||
| 出版社版DOI | ||||||||||||||||||||||||||
| 関連識別子 | https://doi.org/10.1038/srep45502 | |||||||||||||||||||||||||
| 関連名称 | 10.1038/srep45502 | |||||||||||||||||||||||||
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| 出版タイプ | VoR | |||||||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||||||
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| タイトル | Systemic inflammation and family history in relation to the prevalence of type 2 diabetes based on an alternating decision tree | |||||||||||||||||||||||||
| 著者 |
上村, 浩一
× 上村, 浩一× ガイベ, アハマド アンマール
× (勝浦)釜野, 桜子× 山口, 美輪× Bahari, Tirani
× 石津, 将× 森口, 博基
WEKO
1618
× 有澤, 孝吉
WEKO
1248
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| 内容記述 | To investigate unknown patterns associated with type 2 diabetes in the Japanese population, we first used an alternating decision tree (ADTree) algorithm, a powerful classification algorithm from data mining, for the data from 1,102 subjects aged 35–69 years. On the basis of the investigated patterns, we then evaluated the associations of serum high-sensitivity C-reactive protein (hs-CRP) as a biomarker of systemic inflammation and family history of diabetes (negative, positive or unknown) with the prevalence of type 2 diabetes because their detailed associations have been scarcely reported. Elevated serum hs-CRP levels were proportionally associated with the increased prevalence of type 2 diabetes after adjusting for probable covariates, including body mass index and family history of diabetes (P for trend = 0.016). Stratified analyses revealed that elevated serum hs-CRP levels were proportionally associated with increased prevalence of diabetes in subjects without a family history of diabetes (P for trend = 0.020) but not in those with a family history or with an unknown family history of diabetes. Our study demonstrates that systemic inflammation was proportionally associated with increased prevalence of type 2 diabetes even after adjusting for body mass index, especially in subjects without a family history of diabetes. | |||||||||||||||||||||||||
| 書誌情報 |
en : Scientific Reports 巻 7, p. 45502, 発行日 2017-03-31 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||||
| 収録物識別子 | 20452322 | |||||||||||||||||||||||||
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| 出版者 | Springer Nature | |||||||||||||||||||||||||
| 権利情報 | ||||||||||||||||||||||||||
| 権利情報 | © The Author(s) 2017 This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ | |||||||||||||||||||||||||
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| 識別子 | 382017 | |||||||||||||||||||||||||
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| 言語 | eng | |||||||||||||||||||||||||
