{"created":"2024-10-28T08:02:31.709841+00:00","id":2005901,"links":{},"metadata":{"_buckets":{"deposit":"54cd7624-7124-427a-b5c1-f3457ce52847"},"_deposit":{"created_by":7,"id":"2005901","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2005901"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02005901","sets":["1713853213384:1713853296295:1716267876683:1716268551628"]},"author_link":["907","1622","1208"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"正常マウスにおける軸索HCN電流へ麻酔薬が及ぼす影響","subitem_alternative_title_language":"ja"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-01-19","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"2039","bibliographicPageStart":"2033","bibliographicVolumeNumber":"126","bibliographic_titles":[{"bibliographic_title":"Clinical Neurophysiology","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective: The objective was to study the in vivo effects of anesthetic agents on peripheral nerve excitability.\nMethods: Normal male mice were anesthetized by either isoflurane inhalation or a combination of medetomidine, midazolam, and butorphanol intraperitoneal injection (‘‘triple agents’’). Immediately after induction, the tail sensory nerve action potential was recorded and its excitability was monitored.\nResults: Under both anesthetic protocols, there was an interval excitability change by long hyperpolarizing currents. There was greater threshold reduction approximately 30 min post induction, in comparison to immediately post induction. Other excitability parameters were stable over time. Modeling suggested interval suppression of internodal H conductance or leak current.\nConclusions: Anesthetic agents affected responses to long hyperpolarizing currents. Significance: Axonal excitability during intraoperative monitoring may be affected by anesthetic agents. Interpretation of interval excitability changes under anesthesia requires caution, especially with long hyperpolarizing currents.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier","subitem_publisher_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"13882457","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11523403","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA11309888","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_1714461018643":{"attribute_name":"報告番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第3207号"}]},"item_1714461102074":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_1714461118377":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2018-09-13"}]},"item_1714461137393":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"徳島大学"}]}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1718868208704":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"内容要旨・審査要旨・論文本文の公開\n本論文は, 著者Yusuke Osakiの学位論文として提出され, 学位審査・授与の対象となっている。\n学位授与者所属 : 徳島大学大学院医科学教育部（医学専攻）"}]},"item_1718868303842":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"甲医第1381号"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1016/j.clinph.2014.12.025"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.clinph.2014.12.025","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"303188"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"大崎, 裕亮","creatorNameLang":"ja"},{"creatorName":"オオサキ, ユウスケ","creatorNameLang":"ja-Kana"},{"creatorName":"Osaki, Yusuke","creatorNameLang":"en"}],"familyNames":[{"familyName":"大崎","familyNameLang":"ja"},{"familyName":"オオサキ","familyNameLang":"ja-Kana"},{"familyName":"Osaki","familyNameLang":"en"}],"givenNames":[{"givenName":"裕亮","givenNameLang":"ja"},{"givenName":"ユウスケ","givenNameLang":"ja-Kana"},{"givenName":"Yusuke","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"907","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"336321/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/336321/profile-ja.html"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"野寺, 裕之","creatorNameLang":"ja"},{"creatorName":"ノデラ, ヒロユキ","creatorNameLang":"ja-Kana"},{"creatorName":"Nodera, Hiroyuki","creatorNameLang":"en"}],"familyNames":[{"familyName":"野寺","familyNameLang":"ja"},{"familyName":"ノデラ","familyNameLang":"ja-Kana"},{"familyName":"Nodera","familyNameLang":"en"}],"givenNames":[{"givenName":"裕之","givenNameLang":"ja"},{"givenName":"ヒロユキ","givenNameLang":"ja-Kana"},{"givenName":"Hiroyuki","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1208","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40363147","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=40363147"}]},{"creatorNames":[{"creatorName":"Banzrai, Chimeglkham","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"エンドウ, サチコ","creatorNameLang":"ja"},{"creatorName":"エンドウ, サチコ","creatorNameLang":"ja-Kana"},{"creatorName":"Endo, Sachiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"タカヤス, ヒロカズ","creatorNameLang":"ja"},{"creatorName":"タカヤス, ヒロカズ","creatorNameLang":"ja-Kana"},{"creatorName":"Takayasu, Hirokazu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"モリ, アツコ","creatorNameLang":"ja"},{"creatorName":"モリ, アツコ","creatorNameLang":"ja-Kana"},{"creatorName":"Mori, Atsuko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"島谷, 佳光","creatorNameLang":"ja"},{"creatorName":"シマタニ, ヨシミツ","creatorNameLang":"ja-Kana"},{"creatorName":"Shimatani, Yoshimitsu","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"梶, 龍兒","creatorNameLang":"ja"},{"creatorName":"カジ, リュウジ","creatorNameLang":"ja-Kana"},{"creatorName":"Kaji, Ryuji","creatorNameLang":"en"}],"familyNames":[{"familyName":"梶","familyNameLang":"ja"},{"familyName":"カジ","familyNameLang":"ja-Kana"},{"familyName":"Kaji","familyNameLang":"en"}],"givenNames":[{"givenName":"龍兒","givenNameLang":"ja"},{"givenName":"リュウジ","givenNameLang":"ja-Kana"},{"givenName":"Ryuji","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1622","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60224/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/60224/profile-ja.html"},{"nameIdentifier":"00214304","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=00214304"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2018-12-06"}],"displaytype":"detail","filename":"k3207_abstract_review.pdf","filesize":[{"value":"317 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"abstract","url":"https://tokushima-u.repo.nii.ac.jp/record/2005901/files/k3207_abstract_review.pdf"},"version_id":"57bd5892-8922-458f-bc2c-214b5804813f"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2018-12-06"}],"displaytype":"detail","filename":"k3207_fulltext.pdf","filesize":[{"value":"948 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2005901/files/k3207_fulltext.pdf"},"version_id":"901c9601-164c-41c4-a86d-437093fce951"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Axonal excitability","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Anesthetics","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"HCN channel","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Effects of anesthetic agents on in vivo axonal HCN current in normal mice","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of anesthetic agents on in vivo axonal HCN current in normal mice","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1716268551628"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-12-06"},"publish_date":"2018-12-06","publish_status":"0","recid":"2005901","relation_version_is_last":true,"title":["Effects of anesthetic agents on in vivo axonal HCN current in normal mice"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-12T00:33:32.596700+00:00"}