{"created":"2024-10-28T08:21:57.390856+00:00","id":2006165,"links":{},"metadata":{"_buckets":{"deposit":"f991e739-54d9-4b5c-aa42-26a12652b0db"},"_deposit":{"created_by":7,"id":"2006165","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2006165"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02006165","sets":["1713853213384:1713853295607"]},"author_link":["1539"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-01-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"322","bibliographicVolumeNumber":"7","bibliographic_titles":[{"bibliographic_title":"Journal of Clinical & Experimental Dermatology Research","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective: Although monoammonium glycyrrhizinate/glycine/DL-methionine (MG) combination tablets have been widely used widely for the treatment of alopecia areata (AA), there are few studies on efficacious combinations with MG. This study was conducted to determine the efficacy and safety of MG plus 5% carpronium chloride (CC).\nMethods: In the present interventional study, MG tablets plus 5% carpronium chloride (CC) were compared with CC monotherapy in 31 patients with AA.\nResults: There were no significant differences in efficacy between the two groups, and the AA area at 8 and 12 weeks was significantly reduced in both. The results of subanalysis stratified by the presence of allergic factors as determined by IgE level showed that there were also significant decreases in the areas of AA 8 and 12 weeks after the start of the combination therapy in patients with allergic factors (p<0.05). No serious adverse events were observed in either group.\nConclusion: It is suggested that combination therapy with MG and CC has better therapeutic effects than CC monotherapy, with a significant decrease in the area of AA from 4 weeks of treatment even in mild AA patients with allergic factors.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"OMICS International","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"Copyright: © 2015 Kubo Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"21559554","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.4172/2155-9554.1000322"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.4172/2155-9554.1000322","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"312068"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"久保, 宜明","creatorNameLang":"ja"},{"creatorName":"クボ, ヨシアキ","creatorNameLang":"ja-Kana"},{"creatorName":"Kubo, Yoshiaki","creatorNameLang":"en"}],"familyNames":[{"familyName":"久保","familyNameLang":"ja"},{"familyName":"クボ","familyNameLang":"ja-Kana"},{"familyName":"Kubo","familyNameLang":"en"}],"givenNames":[{"givenName":"宜明","givenNameLang":"ja"},{"givenName":"ヨシアキ","givenNameLang":"ja-Kana"},{"givenName":"Yoshiaki","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1539","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60055/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/60055/profile-ja.html"},{"nameIdentifier":"10260069","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=10260069"}]},{"creatorNames":[{"creatorName":"ノギタ, トシタツ","creatorNameLang":"ja"},{"creatorName":"ノギタ, トシタツ","creatorNameLang":"ja-Kana"},{"creatorName":"Nogita, Toshitatsu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"キムラ, イクコ","creatorNameLang":"ja"},{"creatorName":"キムラ, イクコ","creatorNameLang":"ja-Kana"},{"creatorName":"Kimura, Ikuko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"チバ, マミ","creatorNameLang":"ja"},{"creatorName":"チバ, マミ","creatorNameLang":"ja-Kana"},{"creatorName":"Chiba, Mami","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"サカキバラ, カナコ","creatorNameLang":"ja"},{"creatorName":"サカキバラ, カナコ","creatorNameLang":"ja-Kana"},{"creatorName":"Sakakibara, Kanako","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2019-02-19"}],"displaytype":"detail","filename":"clinexpderres_7_1_322.pdf","filesize":[{"value":"2.48 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2006165/files/clinexpderres_7_1_322.pdf"},"version_id":"872d83f8-3523-4977-a60c-70d55091ecd8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Alopecia areata","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Glycyrrhizinate-glycine/DL-methionine combination tablets","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Carpronium chloride","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Allergic factors","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"IgE","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Interventional Evaluation of Monoammonium Glycyrrhizinate-Glycine/DL-Methionine Combination Tablets in Mild Alopecia Areata","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Interventional Evaluation of Monoammonium Glycyrrhizinate-Glycine/DL-Methionine Combination Tablets in Mild Alopecia Areata","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-02-19"},"publish_date":"2019-02-19","publish_status":"0","recid":"2006165","relation_version_is_last":true,"title":["Interventional Evaluation of Monoammonium Glycyrrhizinate-Glycine/DL-Methionine Combination Tablets in Mild Alopecia Areata"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-01-28T07:00:49.474283+00:00"}