{"created":"2024-10-29T00:32:25.071694+00:00","id":2006451,"links":{},"metadata":{"_buckets":{"deposit":"bb0f6f7a-3e52-4625-93c3-23724a60358b"},"_deposit":{"created_by":7,"id":"2006451","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2006451"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02006451","sets":["1713853213384:1713853296295:1716267876683:1716268551628"]},"author_link":["750","248","479","1549"],"control_number":"2006451","item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"十分量の高脂肪食の摂取はストレス誘発性の社会回避行動を改善する","subitem_alternative_title_language":"ja"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-01-14","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"230","bibliographicPageStart":"219","bibliographicVolumeNumber":"219","bibliographic_titles":[{"bibliographic_title":"Life Sciences","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Aims: Psychosocial stress is a form of mental stress associated with human relationships that underlies the pathogenesis of mental disorders such as depression. Previous studies have suggested that intake of energy-dense foods, also known as “palatable foods,” can relieve psychosocial stress. However, it remains unclear whether the volume of palatable food affects abnormal behavior induced by psychosocial stress. In the present study, we aimed to determine whether levels of high-fat food intake significantly influence psychosocial stress using the social-defeat stress (SDS) paradigm.\nMain methods: Mice subjected to SDS ate either a high-fat or normal chow diet for 10 days. Behavioral tests were conducted following the completion of the SDS paradigm. The hypothalamus, liver, and blood were examined post-mortem.\nKey findings: Mice with sufficient intake of high-fat chow immediately following exposure to SDS did not exhibit social avoidance behavior, suggesting that a high-fat diet may improve social behavior. However, inadequate intake of high-fat food, which did not alter cholesterol metabolism or hypothalamic-pituitary-adrenal axis activity, was not associated with such benefits, instead increased anxiety-like behavior.\nSignificance: The results of the present study demonstrate that eating a high-fat diet may attenuate stress, but that this benefit disappears with insufficient intake of high-fat foods. The benefits of a high-fat diet under SDS may be related to cholesterol metabolism in the liver.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"00243205","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11536551","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_1714461018643":{"attribute_name":"報告番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第3260号"}]},"item_1714461102074":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_1714461118377":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2019-03-22"}]},"item_1714461137393":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"徳島大学"}]}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1718868208704":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"内容要旨・審査要旨・論文本文の公開\n本論文は，著者Airi Otsukaの学位論文として提出され，学位審査・授与の対象となっている。\n学位授与者所属 : 徳島大学大学院医科学教育部（医学専攻）"}]},"item_1718868303842":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"甲医第1409号"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1016/j.lfs.2019.01.012"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.lfs.2019.01.012","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"355093"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大塚, 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Tetsuya","creatorNameLang":"en"}],"familyNames":[{"familyName":"志内","familyNameLang":"ja"},{"familyName":"シウチ","familyNameLang":"ja-Kana"},{"familyName":"Shiuchi","familyNameLang":"en"}],"givenNames":[{"givenName":"哲也","givenNameLang":"ja"},{"givenName":"テツヤ","givenNameLang":"ja-Kana"},{"givenName":"Tetsuya","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"479","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"219491/profile-ja.html","nameIdentifierScheme":"徳島大学 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Hiroyoshi","creatorNameLang":"en"}],"familyNames":[{"familyName":"勢井","familyNameLang":"ja"},{"familyName":"セイ","familyNameLang":"ja-Kana"},{"familyName":"Sei","familyNameLang":"en"}],"givenNames":[{"givenName":"宏義","givenNameLang":"ja"},{"givenName":"ヒロヨシ","givenNameLang":"ja-Kana"},{"givenName":"Hiroyoshi","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1549","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60076/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/60076/profile-ja.html"},{"nameIdentifier":"40206602","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=40206602"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2019-06-10"}],"displaytype":"detail","filename":"k3260_abstract_review.pdf","filesize":[{"value":"258 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avoidance","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"high-fat diet","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"HPA axis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"depression","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"anxiety","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Sufficient intake of high-fat food attenuates stress-induced  social avoidance behavior","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Sufficient intake of high-fat food attenuates stress-induced  social avoidance behavior","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1716268551628"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-06-10"},"publish_date":"2019-06-10","publish_status":"0","recid":"2006451","relation_version_is_last":true,"title":["Sufficient intake of high-fat food attenuates stress-induced  social avoidance behavior"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-10T06:26:02.949539+00:00"}