{"created":"2024-10-29T00:33:10.841297+00:00","id":2006460,"links":{},"metadata":{"_buckets":{"deposit":"578cac13-897e-4916-ab56-8e5cd1c9d865"},"_deposit":{"created_by":7,"id":"2006460","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2006460"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02006460","sets":["1713853213384:1713853296295:1716267878536:1716268699858"]},"author_link":["479","1234","864","428","1156","1577","365"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"グレリンの脳室内投与はラットにおいて回転カゴ運動を減少させる","subitem_alternative_title_language":"ja"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-11-05","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"19","bibliographicPageStart":"12","bibliographicVolumeNumber":"87","bibliographic_titles":[{"bibliographic_title":"Peptides","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"There is an increasing interest in elucidating the molecular mechanisms by which voluntary exercise is regulated. In this study, we examined how the central nervous system regulates exercise. We used SPORTS rats, which were established in our laboratory as a highly voluntary murine exercise model. SPORTS rats showed lower levels of serum ghrelin compared with those of the parental line of Wistar rats. Intrac-erebroventricular and intraperitoneal injection of ghrelin decreased wheel-running activity in SPORTS rats. In addition, daily injection of the ghrelin inhibitor JMV3002 into the lateral ventricles of Wistar rats increased wheel-running activity. Co-administration of obestatin inhibited ghrelin-induced increases in food intake but did not inhibit ghrelin-induced suppression of voluntary exercise in rats. Growth hormone secretagogue receptor (GHSR) in the hypothalamus and hippocampus of SPORTS rats was not difference that in control rats. We created an arcuate nucleus destruction model by administering monosodium glutamate (MSG) to neonatal SPORTS rats. Injection of ghrelin into MSG-treated rats decreased voluntary exercise but did not increase food intake, suggesting that wheel-running activity is not controlled by the arcuate nucleus neurons that regulate feeding. These results provide new insights into the mechanism by which ghrelin regulates voluntary activity independent of arcuate nucleus neurons.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier Inc.","subitem_publisher_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"01969781","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA10617807","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA11536405","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_1714461018643":{"attribute_name":"報告番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第3274号"}]},"item_1714461102074":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（栄養学）","subitem_degreename_language":"ja"}]},"item_1714461118377":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2019-03-22"}]},"item_1714461137393":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"徳島大学"}]}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1718868208704":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"内容要旨・審査要旨・論文本文の公開\n本論文は，著者Yumiko Miyatakeの学位論文として提出され，学位審査・授与の対象となっている。\n学位授与者所属 : 徳島大学大学院栄養生命科学教育部（人間栄養科学専攻）"}]},"item_1718868303842":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"甲栄第263号"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1016/j.peptides.2016.11.005"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.peptides.2016.11.005","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"356781"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"宮武, 由実子","creatorNameLang":"ja"},{"creatorName":"ミヤタケ, ユミコ","creatorNameLang":"ja-Kana"},{"creatorName":"Miyatake, Yumiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"志内, 哲也","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"479","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"馬渡, 一諭","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1234","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"トダ, サトミ","creatorNameLang":"ja"},{"creatorName":"トダ, サトミ","creatorNameLang":"ja-Kana"},{"creatorName":"Toda, Satomi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"タニグチ, ヤスコ","creatorNameLang":"ja"},{"creatorName":"タニグチ, ヤスコ","creatorNameLang":"ja-Kana"},{"creatorName":"Taniguchi, Yasuko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"フタミ, アカリ","creatorNameLang":"ja"},{"creatorName":"フタミ, アカリ","creatorNameLang":"ja-Kana"},{"creatorName":"Futami, Akari","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"サトウ, フキコ","creatorNameLang":"ja"},{"creatorName":"サトウ, フキコ","creatorNameLang":"ja-Kana"},{"creatorName":"Sato, Fukiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"黒田, 雅士","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"864","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"セベ, マユ","creatorNameLang":"ja"},{"creatorName":"セベ, マユ","creatorNameLang":"ja-Kana"},{"creatorName":"Sebe, Mayu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"堤, 理恵","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"428","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"原田, 永勝","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1156","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ミノコシ, ヤスヒコ","creatorNameLang":"ja"},{"creatorName":"ミノコシ, ヤスヒコ","creatorNameLang":"ja-Kana"},{"creatorName":"Minokoshi, Yasuhiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"キタムラ, タダヒロ","creatorNameLang":"ja"},{"creatorName":"キタムラ, タダヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Kitamura, Tadahiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ゴトウ, コウロウ","creatorNameLang":"ja"},{"creatorName":"ゴトウ, コウロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Gotoh, Koro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ウエノ, マサキ","creatorNameLang":"ja"},{"creatorName":"ウエノ, マサキ","creatorNameLang":"ja-Kana"},{"creatorName":"Ueno, Masaki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"中屋, 豊","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1577","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"阪上, 浩","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"365","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2019-06-13"}],"displaytype":"detail","filename":"k3274_abstract_review.pdf","filesize":[{"value":"181 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"abstract","url":"https://tokushima-u.repo.nii.ac.jp/record/2006460/files/k3274_abstract_review.pdf"},"version_id":"3461bf16-d416-4f88-a754-1ea2fbd031c9"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2019-06-13"}],"displaytype":"detail","filename":"k3274_fulltext.pdf","filesize":[{"value":"719 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2006460/files/k3274_fulltext.pdf"},"version_id":"8eb3b835-2599-4053-8764-1b1768ece854"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Ghrelin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Voluntary exercise","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Central nervous system","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"SPORTS rat","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Intracerebroventricular injection of ghrelin decreases wheel running activity in rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Intracerebroventricular injection of ghrelin decreases wheel running activity in rats","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1716268699858"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-06-13"},"publish_date":"2019-06-13","publish_status":"0","recid":"2006460","relation_version_is_last":true,"title":["Intracerebroventricular injection of ghrelin decreases wheel running activity in rats"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2024-10-29T00:33:22.953039+00:00"}