{"created":"2024-10-29T00:54:05.794183+00:00","id":2006718,"links":{},"metadata":{"_buckets":{"deposit":"146142e6-9e60-4e8d-aa94-37fe092efa93"},"_deposit":{"created_by":7,"id":"2006718","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2006718"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02006718","sets":["1713853213384:1713853295607"]},"author_link":["683","120","123","787"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"Regulation of cricket metamorphosis","subitem_alternative_title_language":"en"},{"subitem_alternative_title":"Respective roles of Kr-h1, Br and E93 in hemimetabolous metamorphosis","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-08-26","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1783","bibliographicPageStart":"20190225","bibliographicVolumeNumber":"374","bibliographic_titles":[{"bibliographic_title":"Philosophical Transactions of the Royal Society B : Biological Sciences","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Juvenile hormones (JHs) and the genetic interaction between the transcription factors Krüppel homolog 1 (Kr-h1) and Broad (Br) regulate the transformation of insects from immature to adult forms in both types of metamorphosis (holometaboly with a pupal stage versus hemimetaboly with no pupal stage); however, knowledge about the exact instar in which this occurs is limited. Using the hemimetabolous cricket Gryllus bimaculatus (Gb), we demonstrate that a genetic interaction occurs among Gb’Kr-h1, Gb’Br and the adult-specifier transcription factor Gb’E93 from the sixth to final (eighth) nymphal instar. Gb’Kr-h1 and Gb’Br mRNAs were strongly expressed in the abdominal tissues of sixth instar nymphs, with precocious adult moults being induced by Gb’Kr-h1 or Gb’Br knockdown in the sixth instar. Depletion of Gb’Kr-h1 or Gb’Br up-regulates Gb’E93 in the sixth instar. In contrast, Gb’E93 knockdown at the sixth instar prevents nymphs transitioning to adults, instead producing supernumerary nymphs. Gb’E93 also represses Gb’Kr-h1 and Gb’Br expression in the penultimate nymphal instar, demonstrating its important role in adult differentiation. Our results suggest that the regulatory mechanisms underlying the pupal transition in holometabolous insects are evolutionarily conserved in hemimetabolous G. bimaculatus, with the penultimate and final nymphal periods being equivalent to the pupal stage.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Royal Society","subitem_publisher_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"09628436","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"14712970","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA00772905","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1098/rstb.2019.0225"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1098/rstb.2019.0225","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"359157"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"石丸, 善康","creatorNameLang":"ja"},{"creatorName":"イシマル, ヨシヤス","creatorNameLang":"ja-Kana"},{"creatorName":"Ishimaru, Yoshiyasu","creatorNameLang":"en"}],"familyNames":[{"familyName":"石丸","familyNameLang":"ja"},{"familyName":"イシマル","familyNameLang":"ja-Kana"},{"familyName":"Ishimaru","familyNameLang":"en"}],"givenNames":[{"givenName":"善康","givenNameLang":"ja"},{"givenName":"ヨシヤス","givenNameLang":"ja-Kana"},{"givenName":"Yoshiyasu","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"787","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"294054/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/294054/profile-ja.html"},{"nameIdentifier":"50435525","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=50435525"}]},{"creatorNames":[{"creatorName":"友成, さゆり","creatorNameLang":"ja"},{"creatorName":"トモナリ, サユリ","creatorNameLang":"ja-Kana"},{"creatorName":"Tomonari, Sayuri","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"渡辺, 崇人","creatorNameLang":"ja"},{"creatorName":"ワタナベ, タカヒト","creatorNameLang":"ja-Kana"},{"creatorName":"Watanabe, Takahito","creatorNameLang":"en"}],"familyNames":[{"familyName":"渡辺","familyNameLang":"ja"},{"familyName":"ワタナベ","familyNameLang":"ja-Kana"},{"familyName":"Watanabe","familyNameLang":"en"}],"givenNames":[{"givenName":"崇人","givenNameLang":"ja"},{"givenName":"タカヒト","givenNameLang":"ja-Kana"},{"givenName":"Takahito","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"683","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"274817/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/274817/profile-ja.html"},{"nameIdentifier":"30709481","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=30709481"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"野地, 澄晴","creatorNameLang":"ja"},{"creatorName":"ノジ, スミハレ","creatorNameLang":"ja-Kana"},{"creatorName":"Noji, Sumihare","creatorNameLang":"en"}],"familyNames":[{"familyName":"野地","familyNameLang":"ja"},{"familyName":"ノジ","familyNameLang":"ja-Kana"},{"familyName":"Noji","familyNameLang":"en"}],"givenNames":[{"givenName":"澄晴","givenNameLang":"ja"},{"givenName":"スミハレ","givenNameLang":"ja-Kana"},{"givenName":"Sumihare","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"120","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10787/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/10787/profile-ja.html"},{"nameIdentifier":"40156211","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=40156211"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"三戸, 太郎","creatorNameLang":"ja"},{"creatorName":"ミト, タロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Mito, Taro","creatorNameLang":"en"}],"familyNames":[{"familyName":"三戸","familyNameLang":"ja"},{"familyName":"ミト","familyNameLang":"ja-Kana"},{"familyName":"Mito","familyNameLang":"en"}],"givenNames":[{"givenName":"太郎","givenNameLang":"ja"},{"givenName":"タロウ","givenNameLang":"ja-Kana"},{"givenName":"Taro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"123","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10793/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/10793/profile-ja.html"},{"nameIdentifier":"80322254","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=80322254"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2019-10-10"}],"displaytype":"detail","filename":"ptrsb_374_1783_20190225.pdf","filesize":[{"value":"1.99 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2006718/files/ptrsb_374_1783_20190225.pdf"},"version_id":"9b670abe-8606-40ff-8d3b-299352d75f9b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Gryllus bimaculatus","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"insect metamorphosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Krüppel homolog 1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Broad complex","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"E93","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Regulatory mechanisms underlying the specification of the pupal-homologous stage in a hemimetabolous insect","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Regulatory mechanisms underlying the specification of the pupal-homologous stage in a hemimetabolous insect","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-10-10"},"publish_date":"2019-10-10","publish_status":"0","recid":"2006718","relation_version_is_last":true,"title":["Regulatory mechanisms underlying the specification of the pupal-homologous stage in a hemimetabolous insect"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-13T06:31:12.442532+00:00"}