{"created":"2024-10-29T01:19:24.369368+00:00","id":2007045,"links":{},"metadata":{"_buckets":{"deposit":"84f8f215-5348-4be0-ac5a-8a5c6cbe7e63"},"_deposit":{"created_by":7,"id":"2007045","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2007045"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02007045","sets":["1713853213384:1713853295607"]},"author_link":["1533","1561"],"control_number":"2007045","item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"NIRS during cognitive tasks might predict drug response in OCD","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-02-23","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"583","bibliographicPageStart":"577","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"Neuropsychiatric Disease and Treatment","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective: We investigated oxyhemoglobin change in the prefrontal cortex (PFC) of patients with obsessive–compulsive disorder (OCD) who showed different responses to pharmacotherapy during neuropsychological tasks with near-infrared spectroscopy.\nSubjects and methods: A total of 42 patients with OCD (mean age: 35.6±9.6 years, 14 men, 28 women) and healthy control subjects (mean age: 35.4±9.7 years, 13 men, 29 women) were selected. Patients with OCD were divided into three groups (responders to selective serotonin-reuptake inhibitors (SSRIs), responders to SSRIs with antipsychotics, and nonresponders to SSRIs and SSRIs with antipsychotics) based on pharmacological response. We investigated oxyhemoglobin change in the PFC of subjects during Stroop tasks and a verbal fluency test with near-infrared spectroscopy.\nResults: Responders to SSRIs showed smaller activation compared to control subjects during the Stroop incongruent task and verbal fluency test, but not during the Stroop congruent task. In contrast, responders to SSRIs with antipsychotics showed smaller activation compared to control subjects during all three tasks.\nConclusion: Our results suggest that activation of the PFC during Stroop tasks might predict responses to pharmacotherapy of patients with OCD.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Dove Medical Press","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© 2017 Takeda et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"11782021","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.2147/NDT.S127752"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2147/NDT.S127752","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"328535"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"武田, 知也","creatorNameLang":"ja"},{"creatorName":"タケダ, トモヤ","creatorNameLang":"ja-Kana"},{"creatorName":"Takeda, Tomoya","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"住谷, さつき","creatorNameLang":"ja"},{"creatorName":"スミタニ, サツキ","creatorNameLang":"ja-Kana"},{"creatorName":"Sumitani, Satsuki","creatorNameLang":"en"}],"familyNames":[{"familyName":"住谷","familyNameLang":"ja"},{"familyName":"スミタニ","familyNameLang":"ja-Kana"},{"familyName":"Sumitani","familyNameLang":"en"}],"givenNames":[{"givenName":"さつき","givenNameLang":"ja"},{"givenName":"サツキ","givenNameLang":"ja-Kana"},{"givenName":"Satsuki","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1561","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60101/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/60101/profile-ja.html"},{"nameIdentifier":"90346594","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=90346594"}]},{"creatorNames":[{"creatorName":"ハマタニ, サヨ","creatorNameLang":"ja"},{"creatorName":"ハマタニ, サヨ","creatorNameLang":"ja-Kana"},{"creatorName":"Hamatani, Sayo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ヨコセ, ヨウスケ","creatorNameLang":"ja"},{"creatorName":"ヨコセ, ヨウスケ","creatorNameLang":"ja-Kana"},{"creatorName":"Yokose, Yosuke","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"シカタ, メグミ","creatorNameLang":"ja"},{"creatorName":"シカタ, メグミ","creatorNameLang":"ja-Kana"},{"creatorName":"Shikata, Megumi","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"大森, 哲郎","creatorNameLang":"ja"},{"creatorName":"オオモリ, テツロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Ohmori, Tetsuro","creatorNameLang":"en"}],"familyNames":[{"familyName":"大森","familyNameLang":"ja"},{"familyName":"オオモリ","familyNameLang":"ja-Kana"},{"familyName":"Ohmori","familyNameLang":"en"}],"givenNames":[{"givenName":"哲郎","givenNameLang":"ja"},{"givenName":"テツロウ","givenNameLang":"ja-Kana"},{"givenName":"Tetsuro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1533","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60046/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/60046/profile-ja.html"},{"nameIdentifier":"00221135","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=00221135"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2019-12-12"}],"displaytype":"detail","filename":"ndt_13_577.pdf","filesize":[{"value":"496 KB"}],"format":"application/pdf","licensetype":"license_9","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2007045/files/ndt_13_577.pdf"},"version_id":"4aaf88ef-2eed-4da0-b8c6-c54ad615747d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"obsessive–compulsive disorder","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pharmacotherapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"near-infrared spectroscopy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Stroop task","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"verbal fluency test","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Prefrontal cortex activation during neuropsychological tasks might predict response to pharmacotherapy in patients with obsessive–compulsive disorder","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Prefrontal cortex activation during neuropsychological tasks might predict response to pharmacotherapy in patients with obsessive–compulsive disorder","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-12-12"},"publish_date":"2019-12-12","publish_status":"0","recid":"2007045","relation_version_is_last":true,"title":["Prefrontal cortex activation during neuropsychological tasks might predict response to pharmacotherapy in patients with obsessive–compulsive disorder"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-12T00:18:44.644688+00:00"}