{"created":"2024-10-30T09:03:26.445953+00:00","id":2007183,"links":{},"metadata":{"_buckets":{"deposit":"4d40a979-30bc-4db6-96e5-bfc3b3d0fc7d"},"_deposit":{"created_by":7,"id":"2007183","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2007183"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02007183","sets":["1713853213384:1713853295607"]},"author_link":["549","807"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"Analysis of Acid Dissociation Equilibrium of Bupropion by Capillary Zone Electrophoresis After Degradation Under Heat","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-10-20","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"109","bibliographicPageStart":"105","bibliographicVolumeNumber":"37","bibliographic_titles":[{"bibliographic_title":"Chromatography","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"An acid dissociation constant (pKa) of bupropion has been determined in an aqueous solution by capillary zone electrophoresis (CZE). Electrophoretic mobility of bupropion was measured by CZE over its acid-dissociating pH range, and a pKa value has been determined as 8.75±0.02 (mean ± standard error, ionic strength: 0.010 mol dm−3). Although bupropion degrades under heated and alkaline conditions and the degraded species from bupropion coexist in the aqueous solution, the pKa value of bupropion can also be determined by CZE with the residual bupropion without any interference from the degraded species. The pKa value determined after the heat-degradation was 8.74±0.02; the result agreed well with the one determined with the freshly prepared solution. Utilization of the separation characteristics of CZE has been demonstrated with bupropion for the analysis of the fast equilibrium of acid-base reaction under the coexistence of the degraded species.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Society for Chromatographic Sciences","subitem_publisher_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"13483315","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"13428284","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA1137755X","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.15583/jpchrom.2016.009"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.15583/jpchrom.2016.009","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"316008"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"髙栁, 俊夫","creatorNameLang":"ja"},{"creatorName":"タカヤナギ, トシオ","creatorNameLang":"ja-Kana"},{"creatorName":"Takayanagi, Toshio","creatorNameLang":"en"}],"familyNames":[{"familyName":"髙栁","familyNameLang":"ja"},{"familyName":"タカヤナギ","familyNameLang":"ja-Kana"},{"familyName":"Takayanagi","familyNameLang":"en"}],"givenNames":[{"givenName":"俊夫","givenNameLang":"ja"},{"givenName":"トシオ","givenNameLang":"ja-Kana"},{"givenName":"Toshio","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"549","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"241977/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/241977/profile-ja.html"},{"nameIdentifier":"50263554","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=50263554"}]},{"creatorNames":[{"creatorName":"イトウ, ダイチ","creatorNameLang":"ja"},{"creatorName":"イトウ, ダイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Itoh, Daichi","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"水口, 仁志","creatorNameLang":"ja"},{"creatorName":"ミズグチ, ヒトシ","creatorNameLang":"ja-Kana"},{"creatorName":"Mizuguchi, Hitoshi","creatorNameLang":"en"}],"familyNames":[{"familyName":"水口","familyNameLang":"ja"},{"familyName":"ミズグチ","familyNameLang":"ja-Kana"},{"familyName":"Mizuguchi","familyNameLang":"en"}],"givenNames":[{"givenName":"仁志","givenNameLang":"ja"},{"givenName":"ヒトシ","givenNameLang":"ja-Kana"},{"givenName":"Hitoshi","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"807","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"303129/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/303129/profile-ja.html"},{"nameIdentifier":"30333991","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=30333991"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2020-02-25"}],"displaytype":"detail","filename":"jpchrom_37_3_105.pdf","filesize":[{"value":"355 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2007183/files/jpchrom_37_3_105.pdf"},"version_id":"5b76b9c1-28b7-4c8d-8d70-eca307ce782f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Bupropion","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Acid dissociation constant","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Capillary zone electrophoresis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Heat degradation","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Analysis of Acid Dissociation Equilibrium of Bupropion by Capillary Zone Electrophoresis After the Heat-Degradation","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Analysis of Acid Dissociation Equilibrium of Bupropion by Capillary Zone Electrophoresis After the Heat-Degradation","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-02-25"},"publish_date":"2020-02-25","publish_status":"0","recid":"2007183","relation_version_is_last":true,"title":["Analysis of Acid Dissociation Equilibrium of Bupropion by Capillary Zone Electrophoresis After the Heat-Degradation"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-01-29T13:58:10.066784+00:00"}