{"created":"2024-10-30T09:25:16.523640+00:00","id":2007453,"links":{},"metadata":{"_buckets":{"deposit":"697e8cdd-535d-465a-8a16-49047a3831a0"},"_deposit":{"created_by":7,"id":"2007453","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2007453"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02007453","sets":["1713853213384:1713853295607"]},"author_link":["916"],"control_number":"2007453","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-10-04","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"17","bibliographicVolumeNumber":"38","bibliographic_titles":[{"bibliographic_title":"Inflammation and Regeneration","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: A lack of cell or tissue sources hampers regenerative medicine for articular cartilage damage.\nMain text: We review and discuss the possible use of pluripotent stem cells as a new source for future clinical use. Human induced pluripotent stem cells (hiPSCs) have several advantages over human embryonic stem cells (hESCs). Methods for the generation of chondrocytes and cartilage from hiPSCs have been developed. To reduce the cost of this regenerative medicine, allogeneic transplantation is preferable. hiPSC-derived cartilage shows low immunogenicity like native cartilage, because the cartilage is avascular and chondrocytes are segregated by the extracellular matrix. In addition, we consider our experience with the aberrant deposition of lipofuscin or melanin on cartilage during the chondrogenic differentiation of hiPSCs.\nShort conclusion: Cartilage generated from allogeneic hiPSC-derived cartilage can be used to repair articular cartilage damage.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BioMed Central","subitem_publisher_language":"en"},{"subitem_publisher":"Springer Nature","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"18808190","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1186/s41232-018-0075-8"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1186/s41232-018-0075-8","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"357059"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ヤマシタ, アキヒロ","creatorNameLang":"ja"},{"creatorName":"ヤマシタ, アキヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Yamashita, Akihiro","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"玉村, 禎宏","creatorNameLang":"ja"},{"creatorName":"タマムラ, ヨシヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Tamamura, Yoshihiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"玉村","familyNameLang":"ja"},{"familyName":"タマムラ","familyNameLang":"ja-Kana"},{"familyName":"Tamamura","familyNameLang":"en"}],"givenNames":[{"givenName":"禎宏","givenNameLang":"ja"},{"givenName":"ヨシヒロ","givenNameLang":"ja-Kana"},{"givenName":"Yoshihiro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"916","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"337322/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/337322/profile-ja.html"}]},{"creatorNames":[{"creatorName":"モリオカ, ミホ","creatorNameLang":"ja"},{"creatorName":"モリオカ, ミホ","creatorNameLang":"ja-Kana"},{"creatorName":"Morioka, Miho","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Karagiannis, Peter","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"シマ, ノブユキ","creatorNameLang":"ja"},{"creatorName":"シマ, ノブユキ","creatorNameLang":"ja-Kana"},{"creatorName":"Shima, Nobuyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ツマキ, ノリユキ","creatorNameLang":"ja"},{"creatorName":"ツマキ, ノリユキ","creatorNameLang":"ja-Kana"},{"creatorName":"Tsumaki, Noriyuki","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2020-11-26"}],"displaytype":"detail","filename":"ir_38_17.pdf","filesize":[{"value":"2.46 MB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2007453/files/ir_38_17.pdf"},"version_id":"b8b348eb-130b-4601-8245-ef1d3c8da0aa"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Chondrocytes","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Articular cartilage","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Regeneration","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Induced pluripotent stem cells","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Transplantation","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Considerations in hiPSC-derived cartilage for articular cartilage repair","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Considerations in hiPSC-derived cartilage for articular cartilage repair","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-11-26"},"publish_date":"2020-11-26","publish_status":"0","recid":"2007453","relation_version_is_last":true,"title":["Considerations in hiPSC-derived cartilage for articular cartilage repair"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-01-28T04:47:25.232868+00:00"}