{"created":"2024-10-30T09:27:32.852575+00:00","id":2007479,"links":{},"metadata":{"_buckets":{"deposit":"0ed68e0e-9a0e-45c2-9ffb-1911d1e4d01c"},"_deposit":{"created_by":7,"id":"2007479","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2007479"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02007479","sets":["1713853213384:1713853295607"]},"author_link":["947","1227","283","534","1193"],"control_number":"2007479","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-12-02","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"56","bibliographicVolumeNumber":"7","bibliographic_titles":[{"bibliographic_title":"Journal of Intensive Care","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Diaphragm atrophy is observed in mechanically ventilated patients. However, the atrophy is not investigated in other respiratory muscles. Therefore, we conducted a two-center prospective observational study to evaluate changes in diaphragm and intercostal muscle thickness in mechanically ventilated patients.\nMethods: Consecutive adult patients who were expected to be mechanically ventilated longer than 48 h in the ICU were enrolled. Diaphragm and intercostal muscle thickness were measured on days 1, 3, 5, and 7 with ultrasonography. The primary outcome was the direction of change in muscle thickness, and the secondary outcomes were the relationship of changes in muscle thickness with patient characteristics.\nResults: Eighty patients (54 males and 26 females; mean age, 68 ± 14 years) were enrolled. Diaphragm muscle thickness decreased, increased, and remained unchanged in 50 (63%), 15 (19%), and 15 (19%) patients, respectively. Intercostal muscle thickness decreased, increased, and remained unchanged in 48 (60%), 15 (19%), and 17 (21%) patients, respectively. Decreased diaphragm or intercostal muscle thickness was associated with prolonged mechanical ventilation (median difference (MD), 3 days; 95% CI (confidence interval), 1–7 and MD, 3 days; 95% CI, 1–7, respectively) and length of ICU stay (MD, 3 days; 95% CI, 1–7 and MD, 3 days; 95% CI, 1–7, respectively) compared with the unchanged group. After adjusting for sex, age, and APACHE II score, they were still associated with prolonged mechanical ventilation (hazard ratio (HR), 4.19; 95% CI, 2.14–7.93 and HR, 2.87; 95% CI, 1.53–5.21, respectively) and length of ICU stay (HR, 3.44; 95% CI, 1.77–6.45 and HR, 2.58; 95% CI, 1.39–4.63, respectively) compared with the unchanged group.\nConclusions: Decreased diaphragm and intercostal muscle thickness were frequently seen in patients under mechanical ventilation. They were associated with prolonged mechanical ventilation and length of ICU stay.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BioMed Central","subitem_publisher_language":"en"},{"subitem_publisher":"Springer Nature","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"20520492","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1186/s40560-019-0410-4"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1186/s40560-019-0410-4","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"361091"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中西, 信人","creatorNameLang":"ja"},{"creatorName":"ナカニシ, ノブト","creatorNameLang":"ja-Kana"},{"creatorName":"Nakanishi, Nobuto","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"大藤, 純","creatorNameLang":"ja"},{"creatorName":"オオトウ, ジュン","creatorNameLang":"ja-Kana"},{"creatorName":"Oto, Jun","creatorNameLang":"en"}],"familyNames":[{"familyName":"大藤","familyNameLang":"ja"},{"familyName":"オオトウ","familyNameLang":"ja-Kana"},{"familyName":"Oto","familyNameLang":"en"}],"givenNames":[{"givenName":"純","givenNameLang":"ja"},{"givenName":"ジュン","givenNameLang":"ja-Kana"},{"givenName":"Jun","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1193","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60684/profile-ja.html","nameIdentifierScheme":"徳島大学 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Taiga","creatorNameLang":"en"}],"familyNames":[{"familyName":"板垣","familyNameLang":"ja"},{"familyName":"イタガキ","familyNameLang":"ja-Kana"},{"familyName":"Itagaki","familyNameLang":"en"}],"givenNames":[{"givenName":"大雅","givenNameLang":"ja"},{"givenName":"タイガ","givenNameLang":"ja-Kana"},{"givenName":"Taiga","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"534","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10464116","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=10464116"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"西村, 匡司","creatorNameLang":"ja"},{"creatorName":"ニシムラ, マサジ","creatorNameLang":"ja-Kana"},{"creatorName":"Nishimura, 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