{"created":"2024-10-30T09:41:48.060175+00:00","id":2007645,"links":{},"metadata":{"_buckets":{"deposit":"f5967d98-47a1-47fe-8e6c-2e1001b28d4b"},"_deposit":{"created_by":7,"id":"2007645","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2007645"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02007645","sets":["1713829974766:1713855006533:1716426542557:1716426865722","1713853213384:1713853296295:1716267877313:1716268556148"]},"author_link":["982","872","630","851"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"ヒト歯髄幹細胞由来培養上清による皮膚の放射線障害の抑制効果","subitem_alternative_title_language":"ja"},{"subitem_alternative_title":"Dental pulp stem cell factors for treating RISR","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-06-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"7","bibliographicPageStart":"1","bibliographicVolumeNumber":"33","bibliographic_titles":[{"bibliographic_title":"Journal of Oral Health and Biosciences","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Radiation-induced skin ulceration is a frequent complication of radiotherapy for cancer treatment. Stem cells from human exfoliated deciduous teeth (SHEDs) can regenerate various tissues. In this study, we investigated the impact of SHED-conditioned media (SHED-CM) on radiation-induced ulceration. Mouse necks were locally irradiated with a single dose of 15 Gy of radiation. A week after the irradiation, most of the wild-type mice generated ulcer surrounded by severe erythema. Intra-venous administration of SHED-CM effectively inhibited the ulcer formation. Histological examination revealed that SHED-CM treatment inhibited radiation-induced dermal thickness and epithelial hyperplasia. SHED-CM could be a useful treatment option for radiation-induced skin ulceration.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Shikoku Society of Dental Research","subitem_publisher_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"21896682","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_1714461018643":{"attribute_name":"報告番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第3382号"}]},"item_1714461102074":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(歯学)","subitem_degreename_language":"ja"}]},"item_1714461118377":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2020-03-23"}]},"item_1714461137393":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"徳島大学"}]}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1718868208704":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"内容要旨・審査要旨・論文本文の公開\n本論文は,著者Keita Kawarabayashiの学位論文として提出され,学位審査・授与の対象となっている。\n学位授与者所属 : 徳島大学大学院口腔科学教育部(口腔科学専攻)"}]},"item_1718868303842":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"甲口第461号"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.20738/johb.33.1_1"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.20738/johb.33.1_1","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"369398"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"河原林, 啓太","creatorNameLang":"ja"},{"creatorName":"カワラバヤシ, ケイタ","creatorNameLang":"ja-Kana"},{"creatorName":"Kawarabayashi, Keita","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"加納, 史也","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"982","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"橋本, 登","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"872","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ヒビ, ヒデハル","creatorNameLang":"ja"},{"creatorName":"ヒビ, ヒデハル","creatorNameLang":"ja-Kana"},{"creatorName":"Hibi, Hideharu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"岩本, 勉","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"630","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山本, 朗仁","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"851","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2020-06-16"}],"displaytype":"detail","filename":"johb_33_1_1.pdf","filesize":[{"value":"1.19 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2007645/files/johb_33_1_1.pdf"},"version_id":"ab433f9a-b67d-46e6-ab7c-eaafedc1852d"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2020-05-20"}],"displaytype":"detail","filename":"k3382_abstract.pdf","filesize":[{"value":"159 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reactions","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Conditioned media from human dental pulp stem cells prevent radiation-induced skin injury","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Conditioned media from human dental pulp stem cells prevent radiation-induced skin injury","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1716268556148","1716426865722"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-05-20"},"publish_date":"2020-05-20","publish_status":"0","recid":"2007645","relation_version_is_last":true,"title":["Conditioned media from human dental pulp stem cells prevent radiation-induced skin injury"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-01-17T04:07:49.045783+00:00"}