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We present a quantitative method for evaluating cellular organization, using the mouse thymus as a test organ. The thymus is the primary lymphoid organ responsible for generating T cells in vertebrates, and its proper structure and organization is essential for optimal function. Our method, Multitaper Circularly Averaged Spectral Analysis (MiCASA), identifies differences in the tissue-level organization with high sensitivity, including defining a novel type of phenotype by measuring variability as a specific parameter. MiCASA provides a novel and easily implemented quantitative tool for assessing cellular organization.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer Nature","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"20411723","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA12645905","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1038/ncomms15619"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1038/ncomms15619","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"350181"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sornborger, Andrew","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Li, Jie","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Timmons, Cullen","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Lupu, Floria","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Eggenschwiler, Jonathan","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"高浜, 洋介","creatorNameLang":"ja"},{"creatorName":"タカハマ, ヨウスケ","creatorNameLang":"ja-Kana"},{"creatorName":"Takahama, Yousuke","creatorNameLang":"en"}],"familyNames":[{"familyName":"高浜","familyNameLang":"ja"},{"familyName":"タカハマ","familyNameLang":"ja-Kana"},{"familyName":"Takahama","familyNameLang":"en"}],"givenNames":[{"givenName":"洋介","givenNameLang":"ja"},{"givenName":"ヨウスケ","givenNameLang":"ja-Kana"},{"givenName":"Yousuke","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1519","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60028/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/60028/profile-ja.html"},{"nameIdentifier":"20183858","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=20183858"}]},{"creatorNames":[{"creatorName":"Manley, Nancy R.","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2020-12-15"}],"displaytype":"detail","filename":"ncomms_8_15619.pdf","filesize":[{"value":"2.03 MB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2007709/files/ncomms_8_15619.pdf"},"version_id":"bb21711a-9b5a-4c20-a2df-0783f36941d2"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"MiCASA is a new method for quantifying cellular organization","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"MiCASA is a new method for quantifying cellular organization","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-12-15"},"publish_date":"2020-12-15","publish_status":"0","recid":"2007709","relation_version_is_last":true,"title":["MiCASA is a new method for quantifying cellular organization"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-01-29T00:26:13.238873+00:00"}