{"created":"2024-11-22T06:31:12.172769+00:00","id":2008091,"links":{},"metadata":{"_buckets":{"deposit":"27d2fc24-810b-4959-8f89-b8855af00da0"},"_deposit":{"created_by":7,"id":"2008091","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2008091"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02008091","sets":["1713853213384:1713853295607"]},"author_link":["132","416","131"],"control_number":"2008091","item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"Annual change in bone mineral density in COPD","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-02-20","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"644","bibliographicPageStart":"639","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"International Journal of Chronic Obstructive Pulmonary Disease","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Osteoporosis is a well-known comorbidity in COPD. It is associated with poor health status and prognosis. Although the exact pathomechanisms are unclear, osteoporosis is suggested to be either a comorbidity due to shared risk factors with COPD or a systematic effect of COPD with a cause–effect relationship. This study aimed to evaluate whether progression of osteoporosis is synchronized with that of COPD.\nMaterials and methods: Data from 103 patients with COPD included in the Hokkaido COPD cohort study were analyzed. Computed tomography (CT) attenuation values of thoracic vertebrae 4, 7, and 10 were measured using custom software, and the average value (average bone density; ABD4,7,10) was calculated. The percentage of low attenuation volume (LAV%) for each patient was also calculated for evaluation of emphysematous lesions. Annual change in thoracic vertebral CT attenuation, which is strongly correlated with dual-energy X-ray absorptiometry-measured bone mineral density, was compared with that in FEV1.0 or emphysematous lesions.\nResults: In the first CT data set, ABD4,7,10 was significantly correlated with age (ρ=–0.331; p=0.0006), body mass index (BMI; ρ=0.246; p=0.0136), St George’s Respiratory Questionnaire (SGRQ) activity score (ρ=–0.248; p=0.0115), eosinophil count (ρ=0.229; p=0.0198), and LAV% (ρ=–0.372; p=0.0001). However, ABD4,7,10 was not associated with FEV1.0. After adjustment for age, BMI, SGRQ activity score, and eosinophil count, no significant relationship was found between ABD4,7,10 and LAV%. Annual change in ABD4,7,10 was not associated with annual change in LAV% or FEV1.0.\nConclusion: Progression of osteoporosis and that of COPD are not directly related or synchronized with each other.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Dove Medical Press","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© 2018 Goto et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"11782005","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.2147/COPD.S153750"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2147/COPD.S153750","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"336455"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ゴトウ, ケンイチ","creatorNameLang":"ja"},{"creatorName":"ゴトウ, ケンイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Goto, Kenichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"オガワ, エミコ","creatorNameLang":"ja"},{"creatorName":"オガワ, エミコ","creatorNameLang":"ja-Kana"},{"creatorName":"Ogawa, Emiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"シミズ, カオルコ","creatorNameLang":"ja"},{"creatorName":"シミズ, カオルコ","creatorNameLang":"ja-Kana"},{"creatorName":"Shimizu, Kaoruko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"マキタ, ヒロニ","creatorNameLang":"ja"},{"creatorName":"マキタ, ヒロニ","creatorNameLang":"ja-Kana"},{"creatorName":"Makita, Hironi","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"鈴木, 秀宣","creatorNameLang":"ja"},{"creatorName":"スズキ, ヒデノブ","creatorNameLang":"ja-Kana"},{"creatorName":"Suzuki, Hidenobu","creatorNameLang":"en"}],"familyNames":[{"familyName":"鈴木","familyNameLang":"ja"},{"familyName":"スズキ","familyNameLang":"ja-Kana"},{"familyName":"Suzuki","familyNameLang":"en"}],"givenNames":[{"givenName":"秀宣","givenNameLang":"ja"},{"givenName":"ヒデノブ","givenNameLang":"ja-Kana"},{"givenName":"Hidenobu","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"416","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50546710","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=50546710"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"河田, 佳樹","creatorNameLang":"ja"},{"creatorName":"カワタ, ヨシキ","creatorNameLang":"ja-Kana"},{"creatorName":"Kawata, Yoshiki","creatorNameLang":"en"}],"familyNames":[{"familyName":"河田","familyNameLang":"ja"},{"familyName":"カワタ","familyNameLang":"ja-Kana"},{"familyName":"Kawata","familyNameLang":"en"}],"givenNames":[{"givenName":"佳樹","givenNameLang":"ja"},{"givenName":"ヨシキ","givenNameLang":"ja-Kana"},{"givenName":"Yoshiki","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"132","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10813/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/10813/profile-ja.html"},{"nameIdentifier":"70274264","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=70274264"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"仁木, 登","creatorNameLang":"ja"},{"creatorName":"ニキ, ノボル","creatorNameLang":"ja-Kana"},{"creatorName":"Niki, Noboru","creatorNameLang":"en"}],"familyNames":[{"familyName":"仁木","familyNameLang":"ja"},{"familyName":"ニキ","familyNameLang":"ja-Kana"},{"familyName":"Niki","familyNameLang":"en"}],"givenNames":[{"givenName":"登","givenNameLang":"ja"},{"givenName":"ノボル","givenNameLang":"ja-Kana"},{"givenName":"Noboru","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"131","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10811/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/10811/profile-ja.html"},{"nameIdentifier":"80116847","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=80116847"}]},{"creatorNames":[{"creatorName":"ニシムラ, マサハル","creatorNameLang":"ja"},{"creatorName":"ニシムラ, マサハル","creatorNameLang":"ja-Kana"},{"creatorName":"Nishimura, Masaharu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ナカノ, ヤスタカ","creatorNameLang":"ja"},{"creatorName":"ナカノ, ヤスタカ","creatorNameLang":"ja-Kana"},{"creatorName":"Nakano, Yasutaka","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2021-02-09"}],"displaytype":"detail","filename":"copd_13_639.pdf","filesize":[{"value":"716 KB"}],"format":"application/pdf","licensetype":"license_9","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2008091/files/copd_13_639.pdf"},"version_id":"e351068e-5781-4bf9-9040-9d6375e8f70f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"osteoporosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"quantitative CT analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"FEV1.0","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"low attenuation volume","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"automatic analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"systemic effect","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Relationship of annual change in bone mineral density with extent of emphysematous lesions and pulmonary function in patients with COPD","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Relationship of annual change in bone mineral density with extent of emphysematous lesions and pulmonary function in patients with COPD","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-02-09"},"publish_date":"2021-02-09","publish_status":"0","recid":"2008091","relation_version_is_last":true,"title":["Relationship of annual change in bone mineral density with extent of emphysematous lesions and pulmonary function in patients with COPD"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-01-29T07:19:04.335181+00:00"}