| Item type |
文献 / Documents(1) |
| 公開日 |
2020-09-15 |
| アクセス権 |
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アクセス権 |
open access |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版社版DOI |
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関連識別子 |
https://doi.org/10.3390/ijms21176207 |
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関連名称 |
10.3390/ijms21176207 |
| 出版タイプ |
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出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
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|
タイトル |
Involvement of Fusobacterium Species in Oral Cancer Progression : A Literature Review Including Other Types of Cancer |
| 著者 |
藤原, 奈津美
キタムラ, ナオヤ
吉田, 賀弥
ヤマモト, テツヤ
尾崎, 和美
工藤, 保誠
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| 抄録 |
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内容記述 |
Chronic inflammation caused by infections has been suggested to be one of the most important cause of cancers. It has recently been shown that there is correlation between intestinal bacteria and cancer development including metastasis. As over 700 bacterial species exist in an oral cavity, it has been concerning that bacterial infection may cause oral cancer. However, the role of bacteria regarding tumorigenesis of oral cancer remains unclear. Several papers have shown that Fusobacterium species deriving the oral cavities, especially, play a crucial role for the development of colorectal and esophageal cancer. F. nucleatum is a well-known oral bacterium involved in formation of typical dental plaque on human teeth and causing periodontal diseases. The greatest characteristic of F. nucleatum is its ability to adhere to various bacteria and host cells. Interestingly, F. nucleatum is frequently detected in oral cancer tissues. Moreover, detection of F. nucleatum is correlated with the clinical stage of oral cancer. Although the detailed mechanism is still unclear, Fusobacterium species have been suggested to be associated with cell adhesion, tumorigenesis, epithelial-to-mesenchymal transition, inflammasomes, cell cycle, etc. in oral cancer. In this review, we introduce the reports focused on the association of Fusobacterium species with cancer development and progression including oral, esophageal, and colon cancers. |
| キーワード |
|
|
主題 |
Fusobacterium nucleatum |
| キーワード |
|
|
主題 |
oral cancer |
| キーワード |
|
|
主題 |
cancer development and progression |
| 書誌情報 |
en : International Journal of Molecular Sciences
巻 21,
号 17,
p. 6207,
発行日 2020-08-27
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| 収録物ID |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
14220067 |
| 収録物ID |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
16616596 |
| 出版者 |
|
|
出版者 |
MDPI |
| 権利情報 |
|
|
権利情報 |
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| EID |
|
|
識別子 |
380884 |
| 言語 |
|
|
言語 |
eng |
ijms_21_17_6207.pdf (567 KB)
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