| Item type |
文献 / Documents(1) |
| 公開日 |
2021-02-16 |
| アクセス権 |
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アクセス権 |
open access |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版社版DOI |
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関連識別子 |
https://doi.org/10.3390/ijms19020365 |
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関連名称 |
10.3390/ijms19020365 |
| 出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
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タイトル |
Size-Dependent Affinity of Glycine and Its Short Oligomers to Pyrite Surface : A Model for Prebiotic Accumulation of Amino Acid Oligomers on a Mineral Surface |
| 著者 |
Afrin, Rehana
Ganbaatar, Narangerel
アオノ, マサシ
Cleaves II, H. James
矢野, 隆章
ハラ, マサヒコ
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| 抄録 |
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内容記述 |
The interaction strength of progressively longer oligomers of glycine, (Gly), di-Gly, tri-Gly, and penta-Gly, with a natural pyrite surface was directly measured using the force mode of an atomic force microscope (AFM). In recent years, selective activation of abiotically formed amino acids on mineral surfaces, especially that of pyrite, has been proposed as an important step in many origins of life scenarios. To investigate such notions, we used AFM-based force measurements to probe possible non-covalent interactions between pyrite and amino acids, starting from the simplest amino acid, Gly. Although Gly itself interacted with the pyrite surface only weakly, progressively larger unbinding forces and binding frequencies were obtained using oligomers from di-Gly to penta-Gly. In addition to an expected increase of the configurational entropy and size-dependent van der Waals force, the increasing number of polar peptide bonds, among others, may be responsible for this observation. The effect of chain length was also investigated by performing similar experiments using L-lysine vs. poly-L-lysine (PLL), and L-glutamic acid vs. poly-L-glutamic acid. The results suggest that longer oligomers/polymers of amino acids can be preferentially adsorbed on pyrite surfaces. |
| キーワード |
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主題 |
pyrite |
| キーワード |
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主題 |
mineral surface |
| キーワード |
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主題 |
atomic force microscopy |
| キーワード |
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主題 |
unbinding force measurements |
| キーワード |
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主題 |
glycine |
| キーワード |
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主題 |
oligo-glycines |
| キーワード |
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主題 |
peptides |
| キーワード |
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|
主題 |
single molecule interaction |
| キーワード |
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主題 |
origins of life |
| 書誌情報 |
en : International Journal of Molecular Sciences
巻 19,
号 2,
p. 365,
発行日 2018-01-25
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| 収録物ID |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
14220067 |
| 収録物ID |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
16616596 |
| 収録物ID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA12038549 |
| 出版者 |
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出版者 |
MDPI |
| 権利情報 |
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権利情報 |
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| EID |
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識別子 |
371026 |
| 言語 |
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言語 |
eng |
ijms_19_2_365.pdf (1.83 MB)
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