{"created":"2024-11-22T07:25:11.855999+00:00","id":2008573,"links":{},"metadata":{"_buckets":{"deposit":"e44760ce-fd35-44af-9421-56bc3fd2d592"},"_deposit":{"created_by":7,"id":"2008573","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2008573"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02008573","sets":["1713853213384:1713853295607"]},"author_link":["306","1533","1207"],"control_number":"2008573","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-02-13","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"446","bibliographicPageStart":"441","bibliographicVolumeNumber":"16","bibliographic_titles":[{"bibliographic_title":"Neuropsychiatric Disease and Treatment","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Introduction: Although ATP-binding cassette sub-family A member 7 gene (ABCA7) is known to be associated with Alzheimer’s disease, the relationship between ABCA7 and schizophrenia has been unknown.\nMethods: Schizophrenia patients (n = 50; 24 males, 62.1 ± 0.50 years old) and age- and sex-matched healthy controls (n = 50) were recruited for the mRNA analysis. Additionally, a case-control study for the rs3764650 genotypes was performed with 1308 samples (control subjects; n = 527, schizophrenia patients; n = 781). All participants were Japanese, unrelated to each other, and living in the same area.\nResults: The distributions of the rs3764650 genotypes in schizophrenia patients were not different from that of controls. However, the ABCA7 mRNA expression levels in schizophrenia patients were significantly higher than those in controls by a logistic regression analysis. Additionally, the ABCA7 mRNA expression levels in schizophrenia patients were correlated with the rs3764650 genotypes in a dose-dependent manner.\nDiscussion: The ABCA7 mRNA expression levels in peripheral blood with the rs3764650 genotypes may be related to pathological mechanisms in schizophrenia and may be a biological marker for schizophrenia.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Dove Medical Press","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© 2020 Yamazaki et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"11782021","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.2147/NDT.S238471"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2147/NDT.S238471","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"365485"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ヤマザキ, キヨヒロ","creatorNameLang":"ja"},{"creatorName":"ヤマザキ, キヨヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Yamazaki, Kiyohiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ヨシノ, ユウタ","creatorNameLang":"ja"},{"creatorName":"ヨシノ, ユウタ","creatorNameLang":"ja-Kana"},{"creatorName":"Yoshino, Yuta","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"カワベ, ケンタロウ","creatorNameLang":"ja"},{"creatorName":"カワベ, ケンタロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Kawabe, Kentaro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"イブキ, トモマサ","creatorNameLang":"ja"},{"creatorName":"イブキ, トモマサ","creatorNameLang":"ja-Kana"},{"creatorName":"Ibuki, Tomomasa","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"オチ, シンイチロウ","creatorNameLang":"ja"},{"creatorName":"オチ, シンイチロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Ochi, Shinichiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"モリ, ヨウコ","creatorNameLang":"ja"},{"creatorName":"モリ, ヨウコ","creatorNameLang":"ja-Kana"},{"creatorName":"Mori, Yoko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"オザキ, ユウキ","creatorNameLang":"ja"},{"creatorName":"オザキ, ユウキ","creatorNameLang":"ja-Kana"},{"creatorName":"Ozaki, 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Junichi","creatorNameLang":"en"}],"familyNames":[{"familyName":"伊賀","familyNameLang":"ja"},{"familyName":"イガ","familyNameLang":"ja-Kana"},{"familyName":"Iga","familyNameLang":"en"}],"givenNames":[{"givenName":"淳一","givenNameLang":"ja"},{"givenName":"ジュンイチ","givenNameLang":"ja-Kana"},{"givenName":"Junichi","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1207","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70363140","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=70363140"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"大森, 哲郎","creatorNameLang":"ja"},{"creatorName":"オオモリ, テツロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Ohmori, Tetsuro","creatorNameLang":"en"}],"familyNames":[{"familyName":"大森","familyNameLang":"ja"},{"familyName":"オオモリ","familyNameLang":"ja-Kana"},{"familyName":"Ohmori","familyNameLang":"en"}],"givenNames":[{"givenName":"哲郎","givenNameLang":"ja"},{"givenName":"テツロウ","givenNameLang":"ja-Kana"},{"givenName":"Tetsuro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1533","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60046/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/60046/profile-ja.html"},{"nameIdentifier":"00221135","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=00221135"}]},{"creatorNames":[{"creatorName":"上野, 修一","creatorNameLang":"ja"},{"creatorName":"ウエノ, シュウイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Ueno, Shu-ichi","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2021-03-24"}],"displaytype":"detail","filename":"ndt_16_441.pdf","filesize":[{"value":"1.28 MB"}],"format":"application/pdf","licensetype":"license_9","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2008573/files/ndt_16_441.pdf"},"version_id":"c02282a6-dbeb-4122-847d-d8fca54bbbd9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"schizophrenia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ATP-binding cassette sub-family A member 7 gene","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"single nucleotide polymorphism","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"rs3764650","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mRNA expression","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ABCA7 Gene Expression and Genetic Association Study in Schizophrenia","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ABCA7 Gene Expression and Genetic Association Study in Schizophrenia","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-03-24"},"publish_date":"2021-03-24","publish_status":"0","recid":"2008573","relation_version_is_last":true,"title":["ABCA7 Gene Expression and Genetic Association Study in Schizophrenia"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-12T00:18:34.225651+00:00"}