{"created":"2024-11-22T07:39:16.963436+00:00","id":2008733,"links":{},"metadata":{"_buckets":{"deposit":"4024d532-1a76-40b3-b51a-87f63f551d33"},"_deposit":{"created_by":7,"id":"2008733","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2008733"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02008733","sets":["1713853213384:1713853295607"]},"author_link":["294","699","1253","193"],"control_number":"2008733","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-02-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"711","bibliographicPageStart":"704","bibliographicVolumeNumber":"49","bibliographic_titles":[{"bibliographic_title":"Surgery Today","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose\nProlonged postoperative ileus (POI) is a common complication after open abdominal surgery (OAS). Daikenchuto (DKT), a traditional Japanese medicine that peripherally stimulates the neurogenic pathway, is used to treat prolonged POI in Japan. To analyze whether DKT accelerates the recovery from prolonged POI after OAS, we conducted a secondary analysis of three multicenter randomized controlled trials (RCTs).\nMethods\nA secondary analysis of the three RCTs supported by the Japanese Foundation for Multidisciplinary Treatment of Cancer (project numbers 39-0902, 40-1001, 42-1002) assessing the effect of DKT on prolonged POI in patients who had undergone OAS for colon, liver, or gastric cancer was performed. The subgroup included 410 patients with no bowel movement (BM) before the first diet, a DKT group (n = 214), and a placebo group (n = 196). Patients received either 5 g DKT or a placebo orally, three times a day. The primary endpoint was defined as the time from the end of surgery to the first bowel movement (FBM). A sensitivity analysis was also performed on the age, body mass index and dosage as subgroup analyses.\nResults\nThe primary endpoint was significantly accelerated in the DKT group compared with the placebo group (p = 0.004; hazard ratio 1.337). The median time to the FBM was 113.8 h in the placebo group and 99.1 h in the DKT treatment group.\nConclusions\nThe subgroup analysis showed that DKT significantly accelerated the recovery from prolonged POI following OAS.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Japan Surgical Society","subitem_publisher_language":"en"},{"subitem_publisher":"Springer Nature","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"09411291","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"14362813","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA10824685","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open 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幸造","creatorNameLang":"ja"},{"creatorName":"ヨシカワ, コウゾウ","creatorNameLang":"ja-Kana"},{"creatorName":"Yoshikawa, Kouzou","creatorNameLang":"en"}],"familyNames":[{"familyName":"吉川","familyNameLang":"ja"},{"familyName":"ヨシカワ","familyNameLang":"ja-Kana"},{"familyName":"Yoshikawa","familyNameLang":"en"}],"givenNames":[{"givenName":"幸造","givenNameLang":"ja"},{"givenName":"コウゾウ","givenNameLang":"ja-Kana"},{"givenName":"Kouzou","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"294","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80448331","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=80448331"}]},{"creatorNames":[{"creatorName":"カツノ, ヒデトシ","creatorNameLang":"ja"},{"creatorName":"カツノ, ヒデトシ","creatorNameLang":"ja-Kana"},{"creatorName":"Katsuno, Hidetoshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"マエダ, コウタロウ","creatorNameLang":"ja"},{"creatorName":"マエダ, コウタロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Maeda, 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マサキ","creatorNameLang":"ja-Kana"},{"creatorName":"Kitajima, Masaki","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2021-05-21"}],"displaytype":"detail","filename":"st_49_8_704.pdf","filesize":[{"value":"436 KB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2008733/files/st_49_8_704.pdf"},"version_id":"ff28d1ce-e433-42a9-9b55-012fca972329"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Kampo","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Body mass index","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Postoperative ileus","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Daikenchuto accelerates the recovery from prolonged postoperative ileus after open abdominal surgery : a subgroup analysis of three randomized controlled trials","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Daikenchuto accelerates the recovery from prolonged postoperative ileus after open abdominal surgery : a subgroup analysis of three randomized controlled trials","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-05-21"},"publish_date":"2021-05-21","publish_status":"0","recid":"2008733","relation_version_is_last":true,"title":["Daikenchuto accelerates the recovery from prolonged postoperative ileus after open abdominal surgery : a subgroup analysis of three randomized controlled trials"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-04-28T06:11:22.493061+00:00"}