{"created":"2024-12-12T01:14:51.812060+00:00","id":2009091,"links":{},"metadata":{"_buckets":{"deposit":"01644c3d-fda1-44f9-aea9-3b4954922446"},"_deposit":{"created_by":7,"id":"2009091","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2009091"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02009091","sets":["1713853213384:1713853295607"]},"author_link":["1174"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"Oral granuloma with chronic graft-vs-host disease","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-11-26","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"22","bibliographicPageEnd":"5669","bibliographicPageStart":"5663","bibliographicVolumeNumber":"8","bibliographic_titles":[{"bibliographic_title":"World Journal of Clinical Cases","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"BACKGROUND\nOral mucositis is often observed with graft-versus-host disease (GVHD); however, the occurrence of oral granuloma is rare. The rapid increase in granulomatous lesions should be distinguished from malignant tumors in patients with GVHD because malignant diseases can develop in those patients. This case is the youngest pediatric patient with granuloma associated with GVHD.\n\nCASE SUMMARY\nThe patient was a 1-year and 5-mo-old girl who presented to our department for the management of oral nodules. At the age of 5 mo, she was diagnosed with primary immunodeficiency disease, cord blood transplant was performed at 11 mo and bone marrow transplant at 1 year of age. After transplantation, GVHD and oral mucositis developed, and tacrolimus was administered. Interestingly, nodules appeared on the lower lip and buccal mucosa, which spontaneously disappeared. Then, a new nodule appeared on the left lateral border of the tongue. Resection was performed and the histopathological diagnosis was granuloma. The origin of these nodules were considered to be the fibroblasts activated under inflammation caused by GVHD because the calcineurin inhibitor tacrolimus acted on their proliferation.\n\nCONCLUSION\nIt is very important to distinguish oral granulomatous lesions from malignancies if GVHD is present at the base and if immunosuppressive agents and steroids are being administered.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Baishideng Publishing Group","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"23078960","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.12998/wjcc.v8.i22.5663"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.12998/wjcc.v8.i22.5663","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"379189"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"上杉, 篤史","creatorNameLang":"ja"},{"creatorName":"ウエスギ, アツシ","creatorNameLang":"ja-Kana"},{"creatorName":"Uesugi, Atsushi","creatorNameLang":"en"}],"familyNames":[{"familyName":"上杉","familyNameLang":"ja"},{"familyName":"ウエスギ","familyNameLang":"ja-Kana"},{"familyName":"Uesugi","familyNameLang":"en"}],"givenNames":[{"givenName":"篤史","givenNameLang":"ja"},{"givenName":"アツシ","givenNameLang":"ja-Kana"},{"givenName":"Atsushi","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1174","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"364743/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/364743/profile-ja.html"},{"nameIdentifier":"20637061","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=20637061"}]},{"creatorNames":[{"creatorName":"ツシマ, フミヒコ","creatorNameLang":"ja"},{"creatorName":"ツシマ, フミヒコ","creatorNameLang":"ja-Kana"},{"creatorName":"Tsushima, Fumihiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"コダマ, マコト","creatorNameLang":"ja"},{"creatorName":"コダマ, マコト","creatorNameLang":"ja-Kana"},{"creatorName":"Kodama, Makoto","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"クロシマ, タケシ","creatorNameLang":"ja"},{"creatorName":"クロシマ, タケシ","creatorNameLang":"ja-Kana"},{"creatorName":"Kuroshima, Takeshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"サクライ, ジンキョウ","creatorNameLang":"ja"},{"creatorName":"サクライ, ジンキョウ","creatorNameLang":"ja-Kana"},{"creatorName":"Sakurai, Jinkyo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ハラダ, ヒロユキ","creatorNameLang":"ja"},{"creatorName":"ハラダ, ヒロユキ","creatorNameLang":"ja-Kana"},{"creatorName":"Harada, Hiroyuki","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2021-08-19"}],"displaytype":"detail","filename":"wjcc_8_22_5663.pdf","filesize":[{"value":"5.2 MB"}],"format":"application/pdf","licensetype":"license_3","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2009091/files/wjcc_8_22_5663.pdf"},"version_id":"0644a59a-c494-4ef3-8d67-7f0608429af7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Oral granuloma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Graft-versus-host disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Bone marrow transplantation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Primary immunodeficiency disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Tacrolimus","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Case report","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Oral granuloma in a pediatric patient with chronic graft-versus-host disease : A case report","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Oral granuloma in a pediatric patient with chronic graft-versus-host disease : A case report","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-08-19"},"publish_date":"2021-08-19","publish_status":"0","recid":"2009091","relation_version_is_last":true,"title":["Oral granuloma in a pediatric patient with chronic graft-versus-host disease : A case report"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-01-31T04:39:29.648102+00:00"}