{"created":"2024-12-12T01:20:11.736218+00:00","id":2009167,"links":{},"metadata":{"_buckets":{"deposit":"895a5283-5b4e-4d2a-8bd7-4a459c6dad09"},"_deposit":{"created_by":7,"id":"2009167","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2009167"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02009167","sets":["1713853213384:1713853295607"]},"author_link":["852","709","710","1572","882","633","349","677","1433","781","287","175"],"control_number":"2009167","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-06-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"26","bibliographicPageEnd":"2542","bibliographicPageStart":"2531","bibliographicVolumeNumber":"11","bibliographic_titles":[{"bibliographic_title":"Oncotarget","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The efficacy and safety of lenvatinib (LEN) as a second/third-line treatment for unresectable hepatocellular carcinoma (HCC) after sorafenib (SOR) therapy remains unknown. We evaluated the outcomes of second/third-line LEN treatment, investigated the sensitivity of a SOR-resistant HCC cell line (PLC/PRF5-R2) to LEN, and assessed their signal transduction pathways by protein array analysis. We retrospectively enrolled 57 patients with unresectable HCC. Fifty-three radiologically evaluated patients comprised 34 molecular-targeted agent (MTA)-naive (first-line), nine intolerant to SOR (second-line), and 10 resistant to regorafenib (third-line). The objective response rates (ORRs) were 61.8% in first-line, 33.3% in second-line, and 20.0% in third-line groups. The overall survival (OS) in the first-line was significantly longer than that in the third-line group (p < 0.05). Patients with better liver functional reserves (child score, ALBI grade) exhibited higher ORR and longer OS. The IC50 of LEN against PLC/PRF5-R2 was significantly higher than that against PLC/PRF5. LEN significantly inhibited more LEN-related signal transduction pathways in PLC/PRF5 than in PLC/PRF5-R2 cells. This suggests that LEN is active and safe as a second/third-line treatment for unresectable HCC. LEN seems more effective for patients with HCC with better hepatic reserve functions or before MTA-resistance is acquired because of the partial cross-resistance to SOR.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Impact Journals","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"19492553","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.18632/oncotarget.27640"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.18632/oncotarget.27640","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"366569"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"友成, 哲","creatorNameLang":"ja"},{"creatorName":"トモナリ, テツ","creatorNameLang":"ja-Kana"},{"creatorName":"Tomonari, Tetsu","creatorNameLang":"en"}],"familyNames":[{"familyName":"友成","familyNameLang":"ja"},{"familyName":"トモナリ","familyNameLang":"ja-Kana"},{"familyName":"Tomonari","familyNameLang":"en"}],"givenNames":[{"givenName":"哲","givenNameLang":"ja"},{"givenName":"テツ","givenNameLang":"ja-Kana"},{"givenName":"Tetsu","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"709","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"277740/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/277740/profile-ja.html"},{"nameIdentifier":"20556807","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=20556807"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"佐藤, 康史","creatorNameLang":"ja"},{"creatorName":"サトウ, ヤスシ","creatorNameLang":"ja-Kana"},{"creatorName":"Sato, Yasushi","creatorNameLang":"en"}],"familyNames":[{"familyName":"佐藤","familyNameLang":"ja"},{"familyName":"サトウ","familyNameLang":"ja-Kana"},{"familyName":"Sato","familyNameLang":"en"}],"givenNames":[{"givenName":"康史","givenNameLang":"ja"},{"givenName":"ヤスシ","givenNameLang":"ja-Kana"},{"givenName":"Yasushi","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"852","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"321662/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/321662/profile-ja.html"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"田中, 宏典","creatorNameLang":"ja"},{"creatorName":"タナカ, ヒロノリ","creatorNameLang":"ja-Kana"},{"creatorName":"Tanaka, Hironori","creatorNameLang":"en"}],"familyNames":[{"familyName":"田中","familyNameLang":"ja"},{"familyName":"タナカ","familyNameLang":"ja-Kana"},{"familyName":"Tanaka","familyNameLang":"en"}],"givenNames":[{"givenName":"宏典","givenNameLang":"ja"},{"givenName":"ヒロノリ","givenNameLang":"ja-Kana"},{"givenName":"Hironori","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"882","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"325239/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/325239/profile-ja.html"}]},{"creatorNames":[{"creatorName":"田中, 貴大","creatorNameLang":"ja"},{"creatorName":"タナカ, タカヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Tanaka, Takahiro","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"藤野, 泰輝","creatorNameLang":"ja"},{"creatorName":"フジノ, ヤステル","creatorNameLang":"ja-Kana"},{"creatorName":"Fujino, Yasuteru","creatorNameLang":"en"}],"familyNames":[{"familyName":"藤野","familyNameLang":"ja"},{"familyName":"フジノ","familyNameLang":"ja-Kana"},{"familyName":"Fujino","familyNameLang":"en"}],"givenNames":[{"givenName":"泰輝","givenNameLang":"ja"},{"givenName":"ヤステル","givenNameLang":"ja-Kana"},{"givenName":"Yasuteru","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"710","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60747442","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=60747442"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"三井, 康裕","creatorNameLang":"ja"},{"creatorName":"ミツイ, ヤスヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Mitsui, Yasuhiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"三井","familyNameLang":"ja"},{"familyName":"ミツイ","familyNameLang":"ja-Kana"},{"familyName":"Mitsui","familyNameLang":"en"}],"givenNames":[{"givenName":"康裕","givenNameLang":"ja"},{"givenName":"ヤスヒロ","givenNameLang":"ja-Kana"},{"givenName":"Yasuhiro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"781","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"293908/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/293908/profile-ja.html"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"平尾, 章博","creatorNameLang":"ja"},{"creatorName":"ヒラオ, アキヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Hirao, Akihiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"平尾","familyNameLang":"ja"},{"familyName":"ヒラオ","familyNameLang":"ja-Kana"},{"familyName":"Hirao","familyNameLang":"en"}],"givenNames":[{"givenName":"章博","givenNameLang":"ja"},{"givenName":"アキヒロ","givenNameLang":"ja-Kana"},{"givenName":"Akihiro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1433","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"375100/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/375100/profile-ja.html"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"谷口, 達哉","creatorNameLang":"ja"},{"creatorName":"タニグチ, タツヤ","creatorNameLang":"ja-Kana"},{"creatorName":"Taniguchi, Tatsuya","creatorNameLang":"en"}],"familyNames":[{"familyName":"谷口","familyNameLang":"ja"},{"familyName":"タニグチ","familyNameLang":"ja-Kana"},{"familyName":"Taniguchi","familyNameLang":"en"}],"givenNames":[{"givenName":"達哉","givenNameLang":"ja"},{"givenName":"タツヤ","givenNameLang":"ja-Kana"},{"givenName":"Tatsuya","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"633","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70518232","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=70518232"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"岡本, 耕一","creatorNameLang":"ja"},{"creatorName":"オカモト, コウイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Okamoto, Koichi","creatorNameLang":"en"}],"familyNames":[{"familyName":"岡本","familyNameLang":"ja"},{"familyName":"オカモト","familyNameLang":"ja-Kana"},{"familyName":"Okamoto","familyNameLang":"en"}],"givenNames":[{"givenName":"耕一","givenNameLang":"ja"},{"givenName":"コウイチ","givenNameLang":"ja-Kana"},{"givenName":"Koichi","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"349","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"179139/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/179139/profile-ja.html"},{"nameIdentifier":"60531374","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=60531374"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"曽我部, 正弘","creatorNameLang":"ja"},{"creatorName":"ソガベ, マサヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Sogabe, Masahiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"曽我部","familyNameLang":"ja"},{"familyName":"ソガベ","familyNameLang":"ja-Kana"},{"familyName":"Sogabe","familyNameLang":"en"}],"givenNames":[{"givenName":"正弘","givenNameLang":"ja"},{"givenName":"マサヒロ","givenNameLang":"ja-Kana"},{"givenName":"Masahiro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"677","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"274188/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/274188/profile-ja.html"},{"nameIdentifier":"60732790","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=60732790"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"宮本, 弘志","creatorNameLang":"ja"},{"creatorName":"ミヤモト, ヒロシ","creatorNameLang":"ja-Kana"},{"creatorName":"Miyamoto, Hiroshi","creatorNameLang":"en"}],"familyNames":[{"familyName":"宮本","familyNameLang":"ja"},{"familyName":"ミヤモト","familyNameLang":"ja-Kana"},{"familyName":"Miyamoto","familyNameLang":"en"}],"givenNames":[{"givenName":"弘志","givenNameLang":"ja"},{"givenName":"ヒロシ","givenNameLang":"ja-Kana"},{"givenName":"Hiroshi","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"175","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"111468/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/111468/profile-ja.html"},{"nameIdentifier":"90398024","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=90398024"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"六車, 直樹","creatorNameLang":"ja"},{"creatorName":"ムグルマ, ナオキ","creatorNameLang":"ja-Kana"},{"creatorName":"Muguruma, Naoki","creatorNameLang":"en"}],"familyNames":[{"familyName":"六車","familyNameLang":"ja"},{"familyName":"ムグルマ","familyNameLang":"ja-Kana"},{"familyName":"Muguruma","familyNameLang":"en"}],"givenNames":[{"givenName":"直樹","givenNameLang":"ja"},{"givenName":"ナオキ","givenNameLang":"ja-Kana"},{"givenName":"Naoki","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1572","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60123/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/60123/profile-ja.html"},{"nameIdentifier":"90325283","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=90325283"}]},{"creatorNames":[{"creatorName":"カギワダ, ハルミ","creatorNameLang":"ja"},{"creatorName":"カギワダ, ハルミ","creatorNameLang":"ja-Kana"},{"creatorName":"Kagiwada, Harumi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"キタザワ, マサシ","creatorNameLang":"ja"},{"creatorName":"キタザワ, マサシ","creatorNameLang":"ja-Kana"},{"creatorName":"Kitazawa, Masashi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"フクイ, カズヒコ","creatorNameLang":"ja"},{"creatorName":"フクイ, カズヒコ","creatorNameLang":"ja-Kana"},{"creatorName":"Fukui, Kazuhiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ホリモト, カツヒサ","creatorNameLang":"ja"},{"creatorName":"ホリモト, カツヒサ","creatorNameLang":"ja-Kana"},{"creatorName":"Horimoto, Katsuhisa","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"高山, 哲治","creatorNameLang":"ja"},{"creatorName":"タカヤマ, テツジ","creatorNameLang":"ja-Kana"},{"creatorName":"Takayama, Tetsuji","creatorNameLang":"en"}],"familyNames":[{"familyName":"高山","familyNameLang":"ja"},{"familyName":"タカヤマ","familyNameLang":"ja-Kana"},{"familyName":"Takayama","familyNameLang":"en"}],"givenNames":[{"givenName":"哲治","givenNameLang":"ja"},{"givenName":"テツジ","givenNameLang":"ja-Kana"},{"givenName":"Tetsuji","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"287","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"169695/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/169695/profile-ja.html"},{"nameIdentifier":"10284994","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=10284994"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2021-09-07"}],"displaytype":"detail","filename":"onc_11_26_2531.pdf","filesize":[{"value":"2.53 MB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2009167/files/onc_11_26_2531.pdf"},"version_id":"e4e422d4-a9fc-49d9-b6a7-5cacb7e514ea"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"hepatocellular carcinoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"lenvatinib","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"sorafenib","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hepatic reserve function","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"FGFR","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Potential use of lenvatinib for patients with unresectable hepatocellular carcinoma including after treatment with sorafenib : Real-world evidence and in vitro assessment via protein phosphorylation array","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Potential use of lenvatinib for patients with unresectable hepatocellular carcinoma including after treatment with sorafenib : Real-world evidence and in vitro assessment via protein phosphorylation array","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-09-07"},"publish_date":"2021-09-07","publish_status":"0","recid":"2009167","relation_version_is_last":true,"title":["Potential use of lenvatinib for patients with unresectable hepatocellular carcinoma including after treatment with sorafenib : Real-world evidence and in vitro assessment via protein phosphorylation array"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-03T02:35:34.700683+00:00"}