{"created":"2024-12-12T01:39:06.773627+00:00","id":2009406,"links":{},"metadata":{"_buckets":{"deposit":"f33326bf-59cc-45f4-82b5-3e80a3e8cd2d"},"_deposit":{"created_by":7,"id":"2009406","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2009406"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02009406","sets":["1713853213384:1713853296295:1716267876683:1716268551628"]},"author_link":["1511","864","1428","794","431","270","1265","428","365","1536"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"グルタミン酸ナトリウムの食事への添加は健常女性のT1R3味覚受容体遺伝子発現の増加に伴いタンパク質、塩分、糖分摂取などのバランスの取れた食事をもたらす","subitem_alternative_title_language":"ja"},{"subitem_alternative_title":"monosodium glutamate increases T1R3 expression","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3-4","bibliographicPageEnd":"320","bibliographicPageStart":"315","bibliographicVolumeNumber":"68","bibliographic_titles":[{"bibliographic_title":"The Journal of Medical Investigation","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We previously showed that chemotherapy-induced dysgeusia was associated with lingual taste receptor gene expression, and monosodium glutamate (MSG) improved dysgeusia by upregulating taste 1 receptor 3 (T1R3) gene expression. In recent years, decreased taste sensitivity has also been reported in some young people, and these are partly due to their disordered eating habits. From these background, we investigated the effects of MSG supplementation on taste receptor expression and dietary intake in healthy females. Fifteen young healthy volunteers were enrolled for the present crossover study and divided in two groups (dietary supplementation with MSG at 2.7 g / day or 0.27 g / day). The relative expression of T1R3, a subunit of both umami and sweet taste receptors, in the tongue was assessed by quantitative PCR analysis. Food intake was assessed by food frequency questionnaire (FFQg), and body composition was measured using Omron HBF-701. T1R3 expression levels in the tongue and taste sensitivity increased significantly in participants who consumed <10 g of MSG daily, whereas no alteration was observed in participants who consumed >10 g of MSG daily. Furthermore, protein, fat, and carbohydrate (PFC) balance and salt and sugar intake improved by MSG supplementation. In conclusion, MSG supplementation increased T1R3 expression in the tongue and improved dietary balance.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Tokushima University Faculty of Medicine","subitem_publisher_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"13496867","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"13431420","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11166929","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_1714461018643":{"attribute_name":"報告番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第3589号"}]},"item_1714461102074":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_1714461118377":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2022-03-16"}]},"item_1714461137393":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"徳島大学"}]}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1718868208704":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"内容要旨・審査要旨・論文本文の公開\n本論文は，著者Hitoshi Shonoの学位論文として提出され，学位審査・授与の対象となっている。\n著者名英表記誤記あり　(誤)Takahito Azuma→(正)Takahiro Azuma"}]},"item_1718868303842":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"甲医第1530号"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.2152/jmi.68.315"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2152/jmi.68.315","subitem_relation_type_select":"DOI"}}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ベップ, カナ","creatorNameLang":"ja"},{"creatorName":"ベップ, カナ","creatorNameLang":"ja-Kana"},{"creatorName":"Beppu, Kana","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"庄野, 仁志","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1511","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"カワカミ, アユカ","creatorNameLang":"ja"},{"creatorName":"カワカミ, アユカ","creatorNameLang":"ja-Kana"},{"creatorName":"Kawakami, Ayuka","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"タカシ, トモエ","creatorNameLang":"ja"},{"creatorName":"タカシ, トモエ","creatorNameLang":"ja-Kana"},{"creatorName":"Takashi, Tomoe","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ワタナベ, スズノ","creatorNameLang":"ja"},{"creatorName":"ワタナベ, スズノ","creatorNameLang":"ja-Kana"},{"creatorName":"Watanabe, Suzuno","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ヨシダ, アカリ","creatorNameLang":"ja"},{"creatorName":"ヨシダ, アカリ","creatorNameLang":"ja-Kana"},{"creatorName":"Yoshida, Akari","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"黒田, 雅士","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"864","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤本, 知佐","creatorNameLang":"ja"},{"creatorName":"フジモト, チサ","creatorNameLang":"ja-Kana"},{"creatorName":"Fujimoto, Chisa","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"金村, 亮","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1428","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"オオニシ, ヒロキ","creatorNameLang":"ja"},{"creatorName":"オオニシ, ヒロキ","creatorNameLang":"ja-Kana"},{"creatorName":"Ohnishi, Hiroki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"近藤, 英司","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"794","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"東, 貴弘","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"431","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤, 豪","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"270","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"北村, 嘉章","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1265","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"堤, 理恵","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"428","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"阪上, 浩","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"365","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"武田, 憲昭","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1536","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-04-26"}],"displaytype":"detail","filename":"k3589_abstract.pdf","filesize":[{"value":"120 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"abstract","url":"https://tokushima-u.repo.nii.ac.jp/record/2009406/files/k3589_abstract.pdf"},"version_id":"1cff20c6-17f5-43f7-a7c0-d154decafa32"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-04-26"}],"displaytype":"detail","filename":"k3589_review.pdf","filesize":[{"value":"111 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"other","url":"https://tokushima-u.repo.nii.ac.jp/record/2009406/files/k3589_review.pdf"},"version_id":"dadc2a89-f212-4e19-a6b1-10f847394045"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-04-26"}],"displaytype":"detail","filename":"k3589_fulltext.pdf","filesize":[{"value":"458 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2009406/files/k3589_fulltext.pdf"},"version_id":"1a3bbee8-ff1d-49bf-8d2a-c1e3eb3117bb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"monosodium glutamate (MSG)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"T1R3 genes","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"dietary balance","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"taste 1 receptor 3 (T1R3)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"dysgeusia","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Dietary supplementation with monosodium glutamate with dietary balance such as protein, salt and sugar intake with increasing T1R3 taste receptor gene expression in healthy females","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Dietary supplementation with monosodium glutamate with dietary balance such as protein, salt and sugar intake with increasing T1R3 taste receptor gene expression in healthy females","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1716268551628"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-11-29"},"publish_date":"2021-11-29","publish_status":"0","recid":"2009406","relation_version_is_last":true,"title":["Dietary supplementation with monosodium glutamate with dietary balance such as protein, salt and sugar intake with increasing T1R3 taste receptor gene expression in healthy females"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2024-12-12T01:39:16.946802+00:00"}