{"created":"2024-12-12T01:41:52.847162+00:00","id":2009441,"links":{},"metadata":{"_buckets":{"deposit":"1b26df9e-3e3d-4794-aaef-268973e41404"},"_deposit":{"created_by":7,"id":"2009441","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2009441"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02009441","sets":["1713853213384:1713853295607"]},"author_link":["902"],"control_number":"2009441","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-05-21","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageStart":"5426","bibliographicVolumeNumber":"22","bibliographic_titles":[{"bibliographic_title":"International Journal of Molecular Sciences","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Methylation systems have been conserved during the divergence of plants and animals, although they are regulated by different pathways and enzymes. However, studies on the interactions of the epigenomes among evolutionarily distant organisms are lacking. To address this, we studied the epigenetic modification and gene expression of plant chromosome fragments (~30 Mb) in a human–Arabidopsis hybrid cell line. The whole-genome bisulfite sequencing results demonstrated that recombinant Arabidopsis DNA could retain its plant CG methylation levels even without functional plant methyltransferases, indicating that plant DNA methylation states can be maintained even in a different genomic background. The differential methylation analysis showed that the Arabidopsis DNA was undermethylated in the centromeric region and repetitive elements. Several Arabidopsis genes were still expressed, whereas the expression patterns were not related to the gene function. We concluded that the plant DNA did not maintain the original plant epigenomic landscapes and was under the control of the human genome. This study showed how two diverging genomes can coexist and provided insights into epigenetic modifications and their impact on the regulation of gene expressions between plant and animal genomes.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"14220067","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open 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Petr","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"和田, 直樹","creatorNameLang":"ja"},{"creatorName":"ワダ, ナオキ","creatorNameLang":"ja-Kana"},{"creatorName":"Wada, Naoki","creatorNameLang":"en"}],"familyNames":[{"familyName":"和田","familyNameLang":"ja"},{"familyName":"ワダ","familyNameLang":"ja-Kana"},{"familyName":"Wada","familyNameLang":"en"}],"givenNames":[{"givenName":"直樹","givenNameLang":"ja"},{"givenName":"ナオキ","givenNameLang":"ja-Kana"},{"givenName":"Naoki","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"902","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"334009/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/334009/profile-ja.html"}]},{"creatorNames":[{"creatorName":"フクイ, キイチ","creatorNameLang":"ja"},{"creatorName":"フクイ, キイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Fukui, Kiichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Doležel, Jaroslav","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"オオミド, ノブコ","creatorNameLang":"ja"},{"creatorName":"オオミド, ノブコ","creatorNameLang":"ja-Kana"},{"creatorName":"Ohmido, Nobuko","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2021-12-23"}],"displaytype":"detail","filename":"ijms_22_11_5426.pdf","filesize":[{"value":"1.81 MB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2009441/files/ijms_22_11_5426.pdf"},"version_id":"e802b5ff-92c1-41b2-acd0-485047a40d0b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Arabidopsis genome","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DNA methylation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"epigenome","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"human–plant hybrid cell line","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gene expression","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"whole-genome bisulfite sequencing (WGBS)","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Epigenetic Distribution of Recombinant Plant Chromosome Fragments in a Human–Arabidopsis Hybrid Cell Line","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Epigenetic Distribution of Recombinant Plant Chromosome Fragments in a Human–Arabidopsis Hybrid Cell Line","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-12-23"},"publish_date":"2021-12-23","publish_status":"0","recid":"2009441","relation_version_is_last":true,"title":["Epigenetic Distribution of Recombinant Plant Chromosome Fragments in a Human–Arabidopsis Hybrid Cell Line"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-04T06:06:26.179548+00:00"}