{"created":"2024-12-12T02:02:56.774368+00:00","id":2009710,"links":{},"metadata":{"_buckets":{"deposit":"bcc5f999-6ace-46fe-8b66-06bde3ba1837"},"_deposit":{"created_by":7,"id":"2009710","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2009710"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02009710","sets":["1713853213384:1713853295607"]},"author_link":["938"],"control_number":"2009710","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-05-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageStart":"e1900257","bibliographicVolumeNumber":"17","bibliographic_titles":[{"bibliographic_title":"Plasma Processes and Polymers","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Although the externally controllable extracellular supply of the short-lived reactive oxygen and nitrogen species, such as O2•−, •NO, and ONOO−, could potentially manipulate cellular functions, their simple administration to cells is likely to be ineffective due to their rapid deactivation. In this study, we found a method of a continuous supply of O2•−/ONOO− over a few minutes, which is triggered by irradiation of a nonequilibrium atmospheric pressure plasma to commonly used organic buffers (e.g., 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid, HEPES). In addition, a continuous low-dose O2•−/ONOO− supply was shown to induce a physiologically relevant Ca2+ response and subsequently the uptake of a large cation mediated by transient receptor potential channel family member(s). Our results provide a novel approach to the continuous O2•−/ONOO− supply, requiring controllable and mass-volume treatments.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley‐VCH","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"16128869","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11976237","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA1281120X","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open 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Takayuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"カネタカ, ヒロヤス","creatorNameLang":"ja"},{"creatorName":"カネタカ, ヒロヤス","creatorNameLang":"ja-Kana"},{"creatorName":"Kanetaka, Hiroyasu","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"立川, 正憲","creatorNameLang":"ja"},{"creatorName":"タチカワ, マサノリ","creatorNameLang":"ja-Kana"},{"creatorName":"Tachikawa, 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トシロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Kaneko, Toshiro","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-04-15"}],"displaytype":"detail","filename":"ppap_17_10_e1900257.pdf","filesize":[{"value":"1.59 MB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2009710/files/ppap_17_10_e1900257.pdf"},"version_id":"53fbb389-fc64-4c15-afb4-2d6527dc2ee9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"atmospheric pressure plasma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Ca2+ signaling","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"peroxynitrite","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"plasma medicine","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"TRP channel","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Continuous release of O2−/ONOO− in plasma-exposed HEPES-buffered saline promotes TRP channel-mediated uptake of a large cation","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Continuous release of O2−/ONOO− in plasma-exposed HEPES-buffered saline promotes TRP channel-mediated uptake of a large cation","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-04-15"},"publish_date":"2022-04-15","publish_status":"0","recid":"2009710","relation_version_is_last":true,"title":["Continuous release of O2−/ONOO− in plasma-exposed HEPES-buffered saline promotes TRP channel-mediated uptake of a large cation"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-10T07:42:36.774931+00:00"}