{"created":"2024-12-12T07:23:10.788911+00:00","id":2009868,"links":{},"metadata":{"_buckets":{"deposit":"9f74fdc7-b6fa-41cc-b9fd-447e6b909705"},"_deposit":{"created_by":7,"id":"2009868","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2009868"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02009868","sets":["1713853213384:1713853295607"]},"author_link":["653","1248"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-01-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"e002479","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"BMJ Open Diabetes Research & Care","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Introduction\nHealthy diet and physical activity (PA) are essential for preventing type 2 diabetes, particularly, a combination of diet and PA. However, reports on interaction between PA and diet, especially from large epidemiological studies, are limited. We investigated the effect of interaction between PA and macronutrient intake on hemoglobin A1c (HbA1c) levels in the general population.\nResearch design and methods\nWe conducted a cross-sectional study of 55 469 men and women without diabetes who participated in the baseline survey of the Japan Multi-Institutional Collaborative Cohort Study. A self-administered questionnaire ascertained PA and macronutrient intake (carbohydrate, fat, and protein). Multiple linear regression analyses were performed to adjust for confounding variables and examine the interactions. In addition, we conducted a longitudinal study during a 5-year period within a subcohort (n=6881) with accelerometer-assessed PA data.\nResults\nOverall, PA had a weak inverse association (β=−0.00033, p=0.049) and carbohydrate intake had a strong positive association (β=0.00393, p<0.001) with HbA1c. We observed a tendency of interactions between PA and carbohydrate or fat intake, but not protein intake, on HbA1c levels after adjusting for age, sex, study area, total energy intake, alcohol consumption, smoking, and medication for hypertension or hypercholesterolemia (Pinteraction=0.054, 0.006, and 0.156, respectively). The inverse associations between PA and HbA1c level were more evident in participants with high-carbohydrate (or low-fat) intake than in participants with low-carbohydrate (or high-fat) intake. Although further adjustment for body mass index slightly attenuated the above interactions (Pinteraction=0.098 for carbohydrate and 0.068 for fat), the associations between PA and HbA1c level in stratified analyses remained unchanged. Similar associations and interactions were reproduced in the longitudinal study.\nConclusions\nThe present results suggest that the effect of PA on HbA1c levels is modified by intake of macronutrient composition.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BMJ Publishing Group","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"20524897","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1136/bmjdrc-2021-002479"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1136/bmjdrc-2021-002479","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"383792"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"フルカワ, タクマ","creatorNameLang":"ja"},{"creatorName":"フルカワ, タクマ","creatorNameLang":"ja-Kana"},{"creatorName":"Furukawa, Takuma","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ニシダ, ユウイチロウ","creatorNameLang":"ja"},{"creatorName":"ニシダ, ユウイチロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Nishida, Yuichiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ハラ, メグミ","creatorNameLang":"ja"},{"creatorName":"ハラ, メグミ","creatorNameLang":"ja-Kana"},{"creatorName":"Hara, Megumi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"シマノエ, チサト","creatorNameLang":"ja"},{"creatorName":"シマノエ, チサト","creatorNameLang":"ja-Kana"},{"creatorName":"Shimanoe, Chisato","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"コガ, カヨコ","creatorNameLang":"ja"},{"creatorName":"コガ, カヨコ","creatorNameLang":"ja-Kana"},{"creatorName":"Koga, Kayoko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"イワサカ, チハル","creatorNameLang":"ja"},{"creatorName":"イワサカ, チハル","creatorNameLang":"ja-Kana"},{"creatorName":"Iwasaka, Chiharu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ヒガキ, ヤスキ","creatorNameLang":"ja"},{"creatorName":"ヒガキ, ヤスキ","creatorNameLang":"ja-Kana"},{"creatorName":"Higaki, Yasuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"タナカ, ケイタロウ","creatorNameLang":"ja"},{"creatorName":"タナカ, 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ダイスケ","creatorNameLang":"ja-Kana"},{"creatorName":"Matsui, Daisuke","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"クリキ, キヨノリ","creatorNameLang":"ja"},{"creatorName":"クリキ, キヨノリ","creatorNameLang":"ja-Kana"},{"creatorName":"Kuriki, Kiyonori","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ナカムラ, ヤスユキ","creatorNameLang":"ja"},{"creatorName":"ナカムラ, ヤスユキ","creatorNameLang":"ja-Kana"},{"creatorName":"Nakamura, Yasuyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"カドタ, アヤ","creatorNameLang":"ja"},{"creatorName":"カドタ, アヤ","creatorNameLang":"ja-Kana"},{"creatorName":"Kadota, Aya","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"有澤, 孝吉","creatorNameLang":"ja"},{"creatorName":"アリサワ, 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Sakurako","creatorNameLang":"en"}],"familyNames":[{"familyName":"(勝浦)釜野","familyNameLang":"ja"},{"familyName":"(カツウラ)カマノ","familyNameLang":"ja-Kana"},{"familyName":"Katsuura-Kamano","familyNameLang":"en"}],"givenNames":[{"givenName":"桜子","givenNameLang":"ja"},{"givenName":"サクラコ","givenNameLang":"ja-Kana"},{"givenName":"Sakurako","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"653","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"00612574","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=00612574"}]},{"creatorNames":[{"creatorName":"タケウチ, ケンジ","creatorNameLang":"ja"},{"creatorName":"タケウチ, ケンジ","creatorNameLang":"ja-Kana"},{"creatorName":"Takeuchi, Kenji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ワカイ, ケンジ","creatorNameLang":"ja"},{"creatorName":"ワカイ, ケンジ","creatorNameLang":"ja-Kana"},{"creatorName":"Wakai, 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studies","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effect of the interaction between physical activity and estimated macronutrient intake on HbA1c : population-based cross-sectional and longitudinal studies","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-06-02"},"publish_date":"2022-06-02","publish_status":"0","recid":"2009868","relation_version_is_last":true,"title":["Effect of the interaction between physical activity and estimated macronutrient intake on HbA1c : population-based cross-sectional and longitudinal studies"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-14T00:18:54.834491+00:00"}