{"created":"2024-12-12T07:50:16.578102+00:00","id":2010196,"links":{},"metadata":{"_buckets":{"deposit":"0cf5eee0-f735-4dbc-958c-653cf0ff81b6"},"_deposit":{"created_by":7,"id":"2010196","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2010196"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02010196","sets":["1713853213384:1713853295607"]},"author_link":["631","788","927","1545","1536","923"],"item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"Association of phase angle with muscle function and prognosis","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-07-19","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"111798","bibliographicVolumeNumber":"103-104","bibliographic_titles":[{"bibliographic_title":"Nutrition","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective: We aimed to investigate the correlation of phase angle (PhA) with other parameters (e.g., muscle mass/quality/strength and physical function), assess the prognostic relevance of pre-chemoradiotherapy (CRT) PhA, and suggest a reference value of PhA in Asian patients with head and neck cancer (HNC).\nResearch Methods & Procedures: Ninety-six patients with HNC who underwent CRT were divided into two groups, maintained-PhA group and low-PhA group, according to the PhA 25th percentile values by sex. Pretreatment PhA was measured using direct segmental multi-frequency bioelectrical impedance analysis, and muscle quality was assessed using echo intensity in ultrasound images. Correlation of PhA with other parameters was investigated, and between-group differences with respect to adverse events, treatment interruption, and 3-year survival were assessed.\nResults: PhA showed a positive correlation with isometric knee extension force (R = 0.710), handgrip strength (R = 0.649), skeletal muscle mass index (R = 0.620), and maximum gait speed (R = 0.543) (P < 0.001). PhA showed a negative correlation with echo intensity (R = −0.439) and five times sit-to-stand test (R = −0.505) (P < 0.01). The low-PhA group had a higher incidence of severe anemia (52% in low-PhA vs. 17% in maintained-PhA), aspiration (17% vs. 1%), radiotherapy interruption (17% vs. 3%), and poor 3-year survival (47% vs. 81%) than the maintained-PhA group (P < 0.05).\nConclusion: PhA was correlated with muscle mass/quality/strength, and physical function. Low PhA was associated with severe adverse events, treatment interruption, and shorter survival. These findings suggested that 4.6° for men and 4.0° for women may be useful as prognostic reference values in Asian patients with HNC.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© 2022. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"08999007","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA10745727","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA11535297","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open 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function and prognosis in patients with head and neck cancer undergoing chemoradiotherapy"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-13T06:48:12.758596+00:00"}