{"created":"2024-12-12T09:05:50.328887+00:00","id":2010653,"links":{},"metadata":{"_buckets":{"deposit":"61b1c789-8b4a-4d7d-a588-bf7cea819422"},"_deposit":{"created_by":7,"id":"2010653","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2010653"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02010653","sets":["1713853213384:1713853295607"]},"author_link":["1454"],"control_number":"2010653","item_10001_alternative_title_1":{"attribute_name":"タイトル別表記","attribute_value_mlt":[{"subitem_alternative_title":"QTc in burning mouth syndrome","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-07-22","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"Neurology and Neurobiology","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Burning mouth syndrome (BMS) is characterized by a burning sensation of the oral mucosa in the absence of underlying causes. BMS patients can pose a therapeutic challenge to clinicians. Amitriptyline has been a first-line treatment for BMS and is known to prolong corrected QT interval (QTc) in a dose dependent manner. However, little is known about the QTc lengthening effect of amitriptyline at analgesic dosages. The objective of this study was to evaluate changes in QTc in female BMS patients treated with amitriptyline. We conducted a single-center retrospective observational study and evaluated 40 female BMS patients. The QTc interval did not show statistically significant increase with amitriptyline (p=0.1502). However, the change in QTc of amitriptyline-responders was significantly longer than that of non-responders (p=0.0142). The change in QTc may be a non-invasive maker of clinical responses to amitriptyline in female BMS patients.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Science Repository","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository. All rights reserved.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"26137828","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.31487/j.NNB.2018.10.005"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.31487/j.NNB.2018.10.005","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"393255"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"渡邊, 毅","creatorNameLang":"ja"},{"creatorName":"ワタナベ, タケシ","creatorNameLang":"ja-Kana"},{"creatorName":"Watanabe, Takeshi","creatorNameLang":"en"}],"familyNames":[{"familyName":"渡邊","familyNameLang":"ja"},{"familyName":"ワタナベ","familyNameLang":"ja-Kana"},{"familyName":"Watanabe","familyNameLang":"en"}],"givenNames":[{"givenName":"毅","givenNameLang":"ja"},{"givenName":"タケシ","givenNameLang":"ja-Kana"},{"givenName":"Takeshi","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1454","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"381762/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/381762/profile-ja.html"},{"nameIdentifier":"80815217","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=80815217"}]},{"creatorNames":[{"creatorName":"ナガミネ, タカヒコ","creatorNameLang":"ja"},{"creatorName":"ナガミネ, タカヒコ","creatorNameLang":"ja-Kana"},{"creatorName":"Nagamine, Takahiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ミクヅキ, ルウ","creatorNameLang":"ja"},{"creatorName":"ミクヅキ, ルウ","creatorNameLang":"ja-Kana"},{"creatorName":"Mikuzuki, Lou","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"アオタ, ユウマ","creatorNameLang":"ja"},{"creatorName":"アオタ, ユウマ","creatorNameLang":"ja-Kana"},{"creatorName":"Aota, Yuma","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"スガ, タカユキ","creatorNameLang":"ja"},{"creatorName":"スガ, タカユキ","creatorNameLang":"ja-Kana"},{"creatorName":"Suga, Takayuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Tu, Trang T.H","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"タケノシタ, ミホ","creatorNameLang":"ja"},{"creatorName":"タケノシタ, ミホ","creatorNameLang":"ja-Kana"},{"creatorName":"Takenoshita, Miho","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"トヨフク, アキラ","creatorNameLang":"ja"},{"creatorName":"トヨフク, アキラ","creatorNameLang":"ja-Kana"},{"creatorName":"Toyofuku, Akira","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-12-21"}],"displaytype":"detail","filename":"nnb_1_1.pdf","filesize":[{"value":"93.6 KB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2010653/files/nnb_1_1.pdf"},"version_id":"22cb675b-2273-4cfa-bdab-ea05b3590d52"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Amitriptyline","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"autonomic nerve function","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"burning mouth syndrome","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"QTc","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"An increase in corrected QT interval may indicate a good clinical response to amitriptyline in female patients with burning mouth syndrome","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"An increase in corrected QT interval may indicate a good clinical response to amitriptyline in female patients with burning mouth syndrome","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-12-21"},"publish_date":"2022-12-21","publish_status":"0","recid":"2010653","relation_version_is_last":true,"title":["An increase in corrected QT interval may indicate a good clinical response to amitriptyline in female patients with burning mouth syndrome"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-03T04:04:05.733802+00:00"}