{"created":"2024-12-12T09:11:28.635304+00:00","id":2010711,"links":{},"metadata":{"_buckets":{"deposit":"d7a94aa6-a9f7-46cb-82e3-1573d95d2077"},"_deposit":{"created_by":7,"id":"2010711","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2010711"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02010711","sets":["1713853213384:1713853295607"]},"author_link":["1454"],"control_number":"2010711","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-01-17","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"342","bibliographicPageStart":"332","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"Journal of Oral Rehabilitation","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: The nocebo response refers to the phenomenon where non-specific factors, including negative verbal suggestion and treatment expectations, cause adverse events (AE) following a placebo treatment. Non-specific factors are also likely to influence AE occurrence following administration of active pharmacological treatments.\nObjective: This meta-analysis aimed to estimate the nocebo response in dentistry by assessing the AEs prevalence in placebo- and active arms of randomised controlled trials (RCTs) assessing analgesic treatment following third molar (M3) surgery.\nMethods: A systematic search was performed in PubMed, Embase, Scopus, Web of Science and the Cochrane Central Register of Controlled Trials. Eligible studies had to report the number of patients experiencing at least one drug-related AE (patients with AE ≥ 1) separately for the active and placebo arms. The proportion of patients with AE ≥ 1 and drug-related dropouts were pooled, and risk differences (RDs) between patients in the placebo- and active arm were calculated.\nResults: In 50 independent RCTs of 47 identified articles, the pooled rates of patients with AE ≥ 1 were 22.8% in the placebo arm and 20.6% in the active arm. The pooled rates of drug-related dropout were 0.24% in the placebo arm and 0.08% in the active arm. There were no significant RDs in patients with AE ≥ 1 and drug-related dropouts.\nConclusion: These results show that patients in the placebo arm reported AEs to the same extent as patients receiving active treatment, suggesting that most AEs in analgesic medication following M3 surgery may be attributed to the nocebo phenomenon.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"John Wiley & Sons","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"13652842","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11628445","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA00704042","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1111/joor.13414"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/joor.13414","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"393554"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"渡邊, 毅","creatorNameLang":"ja"},{"creatorName":"ワタナベ, タケシ","creatorNameLang":"ja-Kana"},{"creatorName":"Watanabe, Takeshi","creatorNameLang":"en"}],"familyNames":[{"familyName":"渡邊","familyNameLang":"ja"},{"familyName":"ワタナベ","familyNameLang":"ja-Kana"},{"familyName":"Watanabe","familyNameLang":"en"}],"givenNames":[{"givenName":"毅","givenNameLang":"ja"},{"givenName":"タケシ","givenNameLang":"ja-Kana"},{"givenName":"Takeshi","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1454","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"381762/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/381762/profile-ja.html"},{"nameIdentifier":"80815217","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=80815217"}]},{"creatorNames":[{"creatorName":"Sieg, Mette","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Lunde, Sigrid Juhl","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Persson, Mads","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Taneja, Pankaj","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Baad-Hansen, Lene","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Pigg, Maria","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Vase, Lene","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-01-31"}],"displaytype":"detail","filename":"joor_50_4_332.pdf","filesize":[{"value":"779 KB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2010711/files/joor_50_4_332.pdf"},"version_id":"0a03f359-393c-4dae-a7c8-2d8a7c2f0151"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"analgesics","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"long term adverse effects","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"nocebo effect","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"oral surgery","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pain","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"third molar","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Nocebo response in dentistry : A systematic review and meta-analysis of adverse events in analgesic trials of third molar removal","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Nocebo response in dentistry : A systematic review and meta-analysis of adverse events in analgesic trials of third molar removal","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-01-31"},"publish_date":"2023-01-31","publish_status":"0","recid":"2010711","relation_version_is_last":true,"title":["Nocebo response in dentistry : A systematic review and meta-analysis of adverse events in analgesic trials of third molar removal"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-03T04:04:05.925670+00:00"}