{"created":"2025-01-14T00:35:25.426613+00:00","id":2011567,"links":{},"metadata":{"_buckets":{"deposit":"90b6ff90-aca1-48da-9958-51c715e2a4a6"},"_deposit":{"created_by":7,"id":"2011567","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2011567"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02011567","sets":["1713853213384:1713853295607"]},"author_link":["453","1373","1645"],"control_number":"2011567","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-12-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"139","bibliographicPageStart":"134","bibliographicVolumeNumber":"40","bibliographic_titles":[{"bibliographic_title":"​The Journal of ECT","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective:\nElectroconvulsive therapy (ECT) is highly effective for severe psychiatric disorders; however, short seizure durations may lead to ineffective therapy. This retrospective study aimed to examine the risks and benefits of switching to ketamine anesthesia to augment seizure durations during an acute course of ECT.\nMethods:\nWe included 33 patients who underwent ketamine anesthesia due to suboptimal seizures during an acute course of ECT. We assessed seizure duration, stimulus dose, hemodynamic variability, and post-seizure complications before and after switching to ketamine.\nResults:\nAge was significantly associated with suboptimal seizures during ECT (p = 0.040). After switching to ketamine, 32 patients (97%) experienced prolonged seizure duration. Ketamine significantly prolonged both electroencephalogram and motor seizure durations with a mean difference of 34.6 s (95% CI, 26.4 to 42.7; p < 0.001) and 26.6 s (95% CI, 19.6 to 33.6; p < 0.001), respectively. It also significantly reduced stimulus dose (mean difference: −209.5 mC [95% CI, −244.9 to −174.1], p < 0.001). Additionally, maximum changes in systolic blood pressure and heart rate during ECT sessions significantly increased with ketamine (mean difference: 27.2 mmHg [95% CI, 12.0 to 42.4; p = 0.001]; 25.7 bpm [95% CI, 14.5 to 36.8; p < 0.001], respectively). Patients reported more headaches with ketamine (p = 0.041).\nConclusions:\nOur results provide evidence that ketamine as an alternative anesthetic can augment seizure durations in specific patients experiencing suboptimal seizures during an acute course of ECT. However, its use requires greater attention to circulatory management and post-seizure complications.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wolters Kluwer Health","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This is a pre-copyedited, author-produced version of an article accepted for publication in The Journal of ECT. The published version of record Mutoh, Sarara MD; Kinoshita, Michiko MD, PhD; Maeda, Yuki MD; Tanaka, Katsuya MD, PhD . Ketamine as an Alternative Anesthetic for Augmenting Seizure Durations During Electroconvulsive Therapy: A Retrospective Observational Study. The Journal of ECT 40(2): p134-139:10.1097/YCT.0000000000000981, December 8, 2023. is available online at: https://doi.org/10.1097/YCT.0000000000000981.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"10950680","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"15334112","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA11221663","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA12556055","subitem_source_identifier_type":"NCID"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1097/YCT.0000000000000981"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1097/YCT.0000000000000981","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"404374"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ムトウ, サララ","creatorNameLang":"ja"},{"creatorName":"ムトウ, サララ","creatorNameLang":"ja-Kana"},{"creatorName":"Mutoh, Sarara","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"木下, 倫子","creatorNameLang":"ja"},{"creatorName":"キノシタ, ミチコ","creatorNameLang":"ja-Kana"},{"creatorName":"Kinoshita, Michiko","creatorNameLang":"en"}],"familyNames":[{"familyName":"木下","familyNameLang":"ja"},{"familyName":"キノシタ","familyNameLang":"ja-Kana"},{"familyName":"Kinoshita","familyNameLang":"en"}],"givenNames":[{"givenName":"倫子","givenNameLang":"ja"},{"givenName":"ミチコ","givenNameLang":"ja-Kana"},{"givenName":"Michiko","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"453","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"208068/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/208068/profile-ja.html"}]},{"creatorNames":[{"creatorName":"前田, 悠樹","creatorNameLang":"ja"},{"creatorName":"マエダ, ユウキ","creatorNameLang":"ja-Kana"},{"creatorName":"Maeda, Yuki","creatorNameLang":"en"}],"familyNames":[{"familyName":"前田","familyNameLang":"ja"},{"familyName":"マエダ","familyNameLang":"ja-Kana"},{"familyName":"Maeda","familyNameLang":"en"}],"givenNames":[{"givenName":"悠樹","givenNameLang":"ja"},{"givenName":"ユウキ","givenNameLang":"ja-Kana"},{"givenName":"Yuki","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1373","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"406018/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/406018/profile-ja.html"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"田中, 克哉","creatorNameLang":"ja"},{"creatorName":"タナカ, カツヤ","creatorNameLang":"ja-Kana"},{"creatorName":"Tanaka, Katsuya","creatorNameLang":"en"}],"familyNames":[{"familyName":"田中","familyNameLang":"ja"},{"familyName":"タナカ","familyNameLang":"ja-Kana"},{"familyName":"Tanaka","familyNameLang":"en"}],"givenNames":[{"givenName":"克哉","givenNameLang":"ja"},{"givenName":"カツヤ","givenNameLang":"ja-Kana"},{"givenName":"Katsuya","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1645","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60304/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/60304/profile-ja.html"},{"nameIdentifier":"30263841","nameIdentifierScheme":"e-Rad_Researcher","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=30263841"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2024-12-08"}],"displaytype":"detail","filename":"ject_40_2_134.pdf","filesize":[{"value":"519 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2011567/files/ject_40_2_134.pdf"},"version_id":"d0f42960-8b5a-452b-845f-7eee5a261ee1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"augmentation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"alternative anesthetic","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"electroconvulsive therapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ketamine","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"seizure duration","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Ketamine as an Alternative Anesthetic for Augmenting Seizure Durations During Electroconvulsive Therapy : A Retrospective Observational Study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Ketamine as an Alternative Anesthetic for Augmenting Seizure Durations During Electroconvulsive Therapy : A Retrospective Observational Study","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-01-11"},"publish_date":"2024-01-11","publish_status":"0","recid":"2011567","relation_version_is_last":true,"title":["Ketamine as an Alternative Anesthetic for Augmenting Seizure Durations During Electroconvulsive Therapy : A Retrospective Observational Study"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-05T05:03:31.012785+00:00"}