{"created":"2025-01-14T00:47:39.720835+00:00","id":2011690,"links":{},"metadata":{"_buckets":{"deposit":"33363090-29bf-4e7d-a754-633e196773b3"},"_deposit":{"created_by":7,"id":"2011690","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2011690"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02011690","sets":["1713853213384:1713853295607"]},"author_link":["840"],"control_number":"2011690","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-03-20","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"1592","bibliographicPageStart":"1578","bibliographicVolumeNumber":"238","bibliographic_titles":[{"bibliographic_title":"New Phytologist","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The hemibiotrophic fungal plant pathogen Colletotrichum orbiculare is predicted to secrete hundreds of effector proteins when the pathogen infects cucurbit crops, such as cucumber and melon, and tobacco (Nicotiana benthamiana), a distantly related Solanaceae species. Here, we report the identification of sets of C. orbiculare effector genes that are differentially required for fungal virulence to two phylogenetically distant host species.\nThrough targeted gene knockout screening of C. orbiculare ‘core’ effector candidates defined based on in planta gene expression, we identified: four host-specific virulence effectors (named effector proteins for cucurbit infection, or EPCs) that are required for full virulence of C. orbiculare to cucurbit hosts, but not to the Solanaceae host N. benthamiana; and five host-nonspecific virulence effectors, which collectively contribute to fungal virulence to both hosts.\nDuring host infection, only a small subset of genes, including the host-specific EPC effector genes, showed preferential expression on one of the hosts, while gene expression profiles of the majority of other genes, including the five host-nonspecific effector genes, were common to both hosts.\nThis work suggests that C. orbiculare adopts a host-specific effector deployment strategy, in addition to general host-blind virulence mechanisms, for adaptation to cucurbit hosts.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"New Phytologist Foundation","subitem_publisher_language":"en"},{"subitem_publisher":"John Wiley & Sons","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"0028646X","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"14698137","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access"}]},"item_1722929371688":{"attribute_name":"出版社版DOI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"10.1111/nph.18790"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/nph.18790","subitem_relation_type_select":"DOI"}}]},"item_1723180141928":{"attribute_name":"EID","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"394675"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"イノウエ, ヨシヒロ","creatorNameLang":"ja"},{"creatorName":"イノウエ, ヨシヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Inoue, Yoshihiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Phuong Vy, Trinh Thi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Singkaravanit-Ogawa, Suthitar","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Zhang, Ru","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"山田, 晃嗣","creatorNameLang":"ja"},{"creatorName":"ヤマダ, コウジ","creatorNameLang":"ja-Kana"},{"creatorName":"Yamada, Kohji","creatorNameLang":"en"}],"familyNames":[{"familyName":"山田","familyNameLang":"ja"},{"familyName":"ヤマダ","familyNameLang":"ja-Kana"},{"familyName":"Yamada","familyNameLang":"en"}],"givenNames":[{"givenName":"晃嗣","givenNameLang":"ja"},{"givenName":"コウジ","givenNameLang":"ja-Kana"},{"givenName":"Kohji","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"840","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"313993/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/313993/profile-ja.html"}]},{"creatorNames":[{"creatorName":"オガワ, タイキ","creatorNameLang":"ja"},{"creatorName":"オガワ, タイキ","creatorNameLang":"ja-Kana"},{"creatorName":"Ogawa, Taiki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"イシヅカ, ジュンヤ","creatorNameLang":"ja"},{"creatorName":"イシヅカ, ジュンヤ","creatorNameLang":"ja-Kana"},{"creatorName":"Ishizuka, Junya","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ナルサカ, ヨシヒロ","creatorNameLang":"ja"},{"creatorName":"ナルサカ, ヨシヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Narusaka, Yoshihiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"タカノ, ヨシタカ","creatorNameLang":"ja"},{"creatorName":"タカノ, ヨシタカ","creatorNameLang":"ja-Kana"},{"creatorName":"Takano, Yoshitaka","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-07-05"}],"displaytype":"detail","filename":"nph_238_4_1578.pdf","filesize":[{"value":"13.7 MB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tokushima-u.repo.nii.ac.jp/record/2011690/files/nph_238_4_1578.pdf"},"version_id":"c0616a1f-e73b-432b-aa29-dd18c389ebe6"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Colletotrichum orbiculare","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"host specificity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"phytopathogenic fungi","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"transcriptional control","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"virulence effector","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Selective deployment of virulence effectors correlates with host specificity in a fungal plant pathogen","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Selective deployment of virulence effectors correlates with host specificity in a fungal plant pathogen","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-07-05"},"publish_date":"2024-07-05","publish_status":"0","recid":"2011690","relation_version_is_last":true,"title":["Selective deployment of virulence effectors correlates with host specificity in a fungal plant pathogen"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-05T01:20:40.609494+00:00"}