{"created":"2025-01-14T01:32:49.240656+00:00","id":2012174,"links":{},"metadata":{"_buckets":{"deposit":"ad543f60-28f9-4555-a0a3-2cd37bd97c72"},"_deposit":{"created_by":7,"id":"2012174","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2012174"},"status":"published"},"_oai":{"id":"oai:tokushima-u.repo.nii.ac.jp:02012174","sets":["1713853213384:1713853295607"]},"author_link":["415"],"control_number":"2012174","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2024-03-27","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"1343153","bibliographicVolumeNumber":"15","bibliographic_titles":[{"bibliographic_title":"Frontiers in Endocrinology","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective: This study aimed to identify the amount of weight loss needed in patients with obesity to improve metabolic syndrome (MetS), a risk factor for cardiovascular disease (CVD), over a long period of time.\nMethods: A total of 576 patients with obesity were enrolled in this study. Effects of continuous physician-supervised weight loss on the cumulative MetS components excluding abdominal circumference (defined as obesity-related CVD risk score) were investigated during a 5-year follow-up period. The extent of weight loss required to reduce the obesity-related CVD risk components was assessed using receiver operating characteristic (ROC) curve analyses.\nResults: Of the 576 participants, 266 completed 5-year follow-up, with 39.1% and 24.1% of them achieving ≥5.0% and ≥7.5% weight loss at the 5-year follow-up, respectively. The area under the ROC curve for reducing the obesity-related CVD risk components was 0.719 [0.662–0.777] at 1 year and 0.694 [0.613–0.775] at 5 years. The optimal cut-off value for weight loss was 5.0% (0.66 sensitivity and 0.69 specificity) and the value with 0.80 specificity was 7.5% (0.45 sensitivity) at 5 years. Greater reductions in weight were associated with greater improvements in the obesity-related CVD risk score at all follow-up periods (P-trend <0.001). Obesity-related CVD risk score was significantly improved by 5.0–7.5% and ≥7.5% weight loss at 1 year (P = 0.029 and P < 0.001, respectively) and ≥7.5% weight loss at 5 years (P = 0.034).\nConclusions: A weight loss of ≥5.0% at 1 year and ≥7.5% at 5 years could reduce the number of obesity-related CVD risk components in patients with obesity.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Frontiers","subitem_publisher_language":"en"}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"収録物ID","attribute_value_mlt":[{"subitem_source_identifier":"16642392","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1715043197608":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open 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マサシ","creatorNameLang":"ja"},{"creatorName":"タナカ, マサシ","creatorNameLang":"ja-Kana"},{"creatorName":"Tanaka, Masashi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"カトウ, サヤカ","creatorNameLang":"ja"},{"creatorName":"カトウ, サヤカ","creatorNameLang":"ja-Kana"},{"creatorName":"Kato, Sayaka","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ハセガワ, コウジ","creatorNameLang":"ja"},{"creatorName":"ハセガワ, コウジ","creatorNameLang":"ja-Kana"},{"creatorName":"Hasegawa, Koji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"マスダ, イズル","creatorNameLang":"ja"},{"creatorName":"マスダ, イズル","creatorNameLang":"ja-Kana"},{"creatorName":"Masuda, Izuru","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"松久, 宗英","creatorNameLang":"ja"},{"creatorName":"マツヒサ, ムネヒデ","creatorNameLang":"ja-Kana"},{"creatorName":"Matsuhisa, Munehide","creatorNameLang":"en"}],"familyNames":[{"familyName":"松久","familyNameLang":"ja"},{"familyName":"マツヒサ","familyNameLang":"ja-Kana"},{"familyName":"Matsuhisa","familyNameLang":"en"}],"givenNames":[{"givenName":"宗英","givenNameLang":"ja"},{"givenName":"ムネヒデ","givenNameLang":"ja-Kana"},{"givenName":"Munehide","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"415","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"205776/profile-ja.html","nameIdentifierScheme":"徳島大学 教育研究者総覧","nameIdentifierURI":"http://pub2.db.tokushima-u.ac.jp/ERD/person/205776/profile-ja.html"},{"nameIdentifier":"60362737","nameIdentifierScheme":"e-Rad_Researcher","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?qm=60362737"}]},{"creatorNames":[{"creatorName":"コタニ, カズヒコ","creatorNameLang":"ja"},{"creatorName":"コタニ, カズヒコ","creatorNameLang":"ja-Kana"},{"creatorName":"Kotani, Kazuhiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"ノダ, ミツヒコ","creatorNameLang":"ja"},{"creatorName":"ノダ, ミツヒコ","creatorNameLang":"ja-Kana"},{"creatorName":"Noda, Mitsuhiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"サトウ アサハラ, ノリコ","creatorNameLang":"ja"},{"creatorName":"サトウ アサハラ, ノリコ","creatorNameLang":"ja-Kana"},{"creatorName":"Satoh-Asahara, Noriko","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-07-25"}],"displaytype":"detail","filename":"fendo_15_1343153.pdf","filesize":[{"value":"1.11 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follow-up","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Five percent weight loss is a significant 1-year predictor and an optimal 5-year cut-off for reducing the number of obesity-related cardiovascular disease risk components : the Japan Obesity and Metabolic Syndrome Study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Five percent weight loss is a significant 1-year predictor and an optimal 5-year cut-off for reducing the number of obesity-related cardiovascular disease risk components : the Japan Obesity and Metabolic Syndrome Study","subitem_title_language":"en"}]},"item_type_id":"40001","owner":"7","path":["1713853295607"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-07-25"},"publish_date":"2024-07-25","publish_status":"0","recid":"2012174","relation_version_is_last":true,"title":["Five percent weight loss is a significant 1-year predictor and an optimal 5-year cut-off for reducing the number of obesity-related cardiovascular disease risk components : the Japan Obesity and Metabolic Syndrome Study"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2025-02-03T05:39:50.340793+00:00"}