| アイテムタイプ |
文献 / Documents(1) |
| 公開日 |
2025-10-08 |
| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版社版DOI |
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関連識別子 |
https://doi.org/10.1016/j.anaerobe.2025.102961 |
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関連名称 |
10.1016/j.anaerobe.2025.102961 |
| 出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
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タイトル |
Characterization of Lachnoanaerobaculum sanguinis sp. nov., isolated from a blood culture of an acute myeloid leukemia patient with chemotherapy-related bacteremia |
| 著者 |
Suenari, Yumi
Matsubara, Toshiyuki
廣島, 佑香
Pahlevi, Muhammad Reza
Shimada, Hiroka
Ochi, Yuto
岡田, 直人
WEKO
523
e-Rad_Researcher
30623269
| ja |
岡田, 直人
岡田, 直人
ISNI
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| ja-Kana |
オカダ, ナオト
オカダ, ナオト
|
| en |
Okada, Naoto
Okada, Naoto
|
Search repository
Sato, Masami
藤猪, 英樹
住友, 倫子
Kishimoto, Hidehiro
村上, 明一
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| 抄録 |
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内容記述 |
Objective: This study was to characterize and determine the classification of the novel strain TM49T, isolated from a blood culture of a patient who developed bacteremia while receiving high-dose cytarabine chemotherapy for acute myeloid leukemia.
Methods: The novel strain TM49T was characterized at the species level through a polyphasic taxonomic analysis, incorporating morphological, physiological, biochemical, phylogenetic, and genome sequence analyses.
Results: 16S rRNA gene sequence analysis revealed that the strain belonged to the genus Lachnoanaerobaculum. The 16S rRNA gene sequence of strain TM49T was observed to be most similar to that of "Lachnoanaerobaculum gingivalis" strain ChDC B114T (99.2 %). Strain TM49T formed circular, glossy, slightly milky colonies with an undulate margin on BD™ Columbia Agar containing 5 % sheep blood after 48 h at 37 °C, exhibiting less spreading compared to species of the genus Lachnoanaerobaculum. The major fatty acids of strain TM49T were C16:0, C14:0, C18:1 ω9c DMA, and C18:1 ω7c DMA. The draft genome sequence of strain TM49T was 2,821,554 bp in length, with a G + C content of 36.4. Digital DNA-DNA hybridization values between strain TM49T and “L. gingivalis” ChDC B114T, L. umeaense CD3: 22T, L. orale N1T, and L. saburreum CCUG 28089T were 52.2 %, 29.7 %, 26.2 %, and 24.5 %, respectively. The Orthologous Average Nucleotide Identity values between strain TM49T and “L. gingivalis” ChDC B114T, L. umeaense CD3: 22T, L. orale N1T, and L. saburreum CCUG 28089T were 93.1 %, 84.9 %, 83.2 %, and 81.5 %, respectively.
Conclusion: Strain TM49T (JCM 36186T = DSM 116945T) was found to be distinct from previously described species of the genus Lachnoanaerobaculum. Therefore, it is proposed as a new species, Lachnoanaerobaculum sanguinis sp. Nov., with strain TM49T as the type strain (= JCM 36186T = DSM 116945T). |
| キーワード |
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主題 |
Genus Lachnoanaerobaculum |
| キーワード |
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主題 |
Bacteremia |
| キーワード |
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主題 |
High-dose chemotherapy |
| 書誌情報 |
en : Anaerobe
巻 93,
p. 102961,
発行日 2025-04-14
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| 収録物ID |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
10958274 |
| 収録物ID |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
10759964 |
| 収録物ID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA1153769X |
| 収録物ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11101129 |
| 出版者 |
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出版者 |
Elsevier |
| 権利情報 |
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|
権利情報 |
This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| EID |
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|
識別子 |
433261 |
| 言語 |
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|
言語 |
eng |
anaerobe_93_102961.pdf (3.6 MB)
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